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Biomedical subjects

D S Guliamov

Publications and source records attributed to D S Guliamov.

At least 19 recordsLinked to original sources

[Clinical picture and treatment of mediastinitis after correction of congenital heart diseases in open heart surgery].

Postoperative purulent mediastinitis was observed by the authors in 43 out of 1110 patients. Specific features of the clinical picture and course of this complication are described. The "closed" method of treatment was used in 20 patients. Five of them died from intoxication and arrosive bleeding. The "open" method of treatment of mediastinitis was used in 23 patients with no lethal outcomes.

Adolescent↗

["Open" surgery of mitral heart diseases complicated by pulmonary hypertension].

Under analysis were the results of 386 operations on the "open" heart made for mitral diseases complicated by pulmonary hypertension of different degrees. Prosthetics of the mitral valve was performed in 251 patients, in 135 patients the so-called "organ-saving" correction of the defect was fulfilled. The decision on the method of the defect correction depends on the anatomical particularities, morphological alterations of the valvular apparatus. The main place among the causes of postoperative lethality (9-11%) is occupied by cardiac insufficiency and renohepatic failure which are noted mainly in patients of the IVth functional class.

Heart Valve Prosthesis Implantation↗

[Surgical treatment of atrial septal defects and associated congenital heart diseases].

The results of radical correction of interatrial septum defects and heart diseases associated with it were analyzed after treatment of 502 patients at the age from 5 to 48 years. In most cases (58.4%) the patients were adults. The isolated defect of the interatrial septum was diagnosed in 377 patients. Correction of the defect was performed in 82 patients (16.3%) under mild hypothermia and 420 patients (83.6%) were operated upon under conditions of artificial circulation. General lethality was 7.7%.

Adolescent↗

[Surgical methods for correcting partial anomalous drainage of the pulmonary veins during artificial circulation].

The authors share their experiences with surgical treatment of 42 patients with different anatomical variants of the partial anomalous drainage of the pulmonary veins. Specific features of the surgical strategy are described depending on the level of confluence of the pulmonary veins, especially if the mouths of the abnormally falling pulmonary veins and the interatrial septum defect are far from each other. Good immediate and nearest results were obtained.

Adolescent↗

[The echocardiographic indices of patients with tetralogy of Fallot before and after the suturing of subclavian-pulmonary anastomoses].

Echocardiography was made in 69 patients with Fallot's tetrad before and 2 weeks-15 years after forming subclavian-pulmonary anastomosis (SPA). By the anastomosis function the patients were divided into 2 groups. 47 patients with satisfactory function of the anastomosis 3.2+ -1.06 years after the operation comprised group 1. 22 patients of group 2 had marked cyanotic syndrome due to thrombosis of the anastomosis 9.45 + -2.45 years after surgery. Echocardiography in Fallot's tetrad patients before and after SPA specified anatomic components of the defect, size of the left heart and results of the operation.

Adolescent↗

[Inter-arterial anastomosis in dextral position of the aortic arch in patients with tetralogy of Fallot].

The article discusses the results of formation of inter-arterial anastomoses in 58 (12.7%) patients with a severe form of Fallot's tetralogy in dextra-position of the arch of the aorta. The specific features of the course and diagnosis of dextra-position of the aortic arch in Fallot's tetralogy are analysed, and the significance of radiologic and echocardiographic examination in the choice of the position and type of interarterial anastomoses is determined. It is proved that Blalock-Taussig's anastomoses must be formed on the side opposite to the aortic arch, while shunting operations must be carried out on the side on which the arch of the aorta is located.

Abnormalities, Multiple↗

[Reoperations in bradyarrhythmic forms of disorders of heart conductivity].

Under analysis were causes of reoperations in bradyarrhythmic forms of disturbances of conductivity of the heart. 565 operations connected with electrocardiostimulation were performed on 276 patients. Reoperations in patients with the myocardial stimulation were made on 63 patients, with the endocardial stimulation--in 226 patients. Causes of reoperations were as follows: depletion of the source of ECS--31.5%; dislocation of the electrode--8.2%; damage of the electrode--15%, suppuration of the bed, decubitus of the stimulator--28.8%; competing rate--7.4%; break of the contact in the connecting system of the electrode and cardiostimulator--9.4%.

Bradycardia↗

A new method of plastic surgery of the right ventricular outflow tract and pulmonary artery in experiment.

A new method of plastic surgery of the right ventricular outflow tract and the pulmonary artery without use of extracorporeal circulation (occlusion of main arteries) was tested in experiments carried out in 28 dogs. The method involves previous suture of a patch to the site selected for plastic surgery and, using an instrument designed by the authors, excision of the necessary part of the ventricular wall and pulmonary artery. The instrument consists of two handles, similar to those of pincers, and working on a pivot, with oval cavities on the inner sides of its elongated grasping jaws. The tip of lower jaw features a sloping edge to enable perforation of the outer wall of the heart. By pulling together the handles, connected with a spring, the jaws close excising the appropriate part of the heart. The depth of insertion of the jaws into the heart cavity's controlled by means of a graded scale on the outer side of the upper jaw. Using this technique it is possible to perform surgery even of extensive myocardial defects quickly, safely, with virtually no trauma and minimal loss of blood, and to remove large segments of the hypertrophic myocardium while retaining intracardiac circulation, without the need for extracorporeal circulation.

Animals↗

Energy value of glucose and lactate for the myocardium in patients with mitral stenosis.

In 145 patients with severe mitral stenosis the levels of energy substrates and adenile nucleotides were determined in biopsy samples from the left atrial appendage obtained during mitral commissurotomy. Patients with the latest stage (stage IV according to Bakulev and Damir's classification) of mitral stenosis displayed, in comparison with stage III patients, activation of aerobic oxidation of glucose, lactate and succinate, together with a moderate reduction in myocardial glucose, lactate and pyruvate levels. ATP content and myocardial adenile nucleotide pool did not change with progression of the disease.

Adenine Nucleotides↗

Comparison of various approaches used to assess the functional state of the cardiac and respiratory system in patients undergoing rehabilitation following cardiac surgery.

A total of 338 patients aged 10 to 56 years, who had undergone various cardiac operations, were divided, on the basis of a spiroergometric examination, performed together with the determination of maximal oxygen intake (MOI), into 4 functional classes. Determination of functional aerobic impairment, i.e. the magnitude of deviation of the established MOI value from that theoretically anticipated in view of the patient's age and sex, made it possible to determine the degree of decrease in the reserve capacity of the patient's cardiac and respiratory system (CRS). Comprehensive assessment of the functional state of the CRS, while taking into account the patient's individual characteristics, is a prerequisite for a differentiated quantitative approach to the design of rehabilitation programmes.

Adolescent↗

[Vasoactive hormone metabolism in the lungs of patients with congenital heart defects].

The role of pulmonary metabolism of adrenaline, noradrenaline (NA), serotonin and histamine in the pathogenesis of hemodynamic disorders was examined in relation to the magnitude of intracardiac discharge (ID) in 30 patients with septal defects. Irrespective of the magnitude of arteriovenous ID, pulmonary tissue deactivation of NA is shown to be disrupted. Where ID averages 7.7 +/- 2.1 1/min, venous blood NA level is 59.8% higher (p less than 0.05) than that of patients with average ID of 3.1 +/- 0.7 1/min. A positive correlation (r = 0.51) is demonstrated between venous NA levels and ID in the latter group. The data obtained suggest that high ID values are associated with disturbed pulmonary metabolism and increased arterial levels of serotonin and NA, a significant contribution to the development of functional and morphologic vascular disorders of systemic and pulmonary circulation.

Adolescent↗