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Biomedical subjects

D S Hall

Publications and source records attributed to D S Hall.

18 recordsLinked to original sources
PubMed2000

Allograft rejection results from a failed attempt by the immune system to protect foreign tissue.

The focus of our research is to understand the immune response to foreign tissue. We believe that a dichotomy exists within the immune response to an allograft such that part of the response is dedicated to the protection of the graft. Nevertheless, in a dominantly graft-aggressive environment, rejection typically ensues. In this article, we describe models that have been set up to test directly the ability of potentially protective aspects of the immune response to prevent allograft rejection. We discuss our data in the context of a growing body of exciting and often controversial literature.

Animals↗
PubMed1996

Interactions between nurses and patients on ventilators.

BACKGROUND: Although the effectiveness of communication between nurses and ventilated patients has been identified by the American Association of Critical-Care Nurses as an area of concern, there are few reports of research in this area. OBJECTIVES: To examine the interactions between nurses and patients on ventilators and the relationship between characteristics of these nurses and their communication with patients. METHODS: An analytical, cross-sectional, experimental design was used to examine the work experience of 30 nurses with ventilated patients, the perceived level of consciousness of their ventilated patients, and the actions and reactions of nurses in relation to these patients. RESULTS: Significant correlations were found between the nurse's perception of the patient's degree of responsiveness and the number of positive and negative interactions with the patient, and between the length of time the nurse cared for the patient and the number of positive nurse reactions. Interaction patterns are also apparent from the data collected. CONCLUSIONS: Findings suggest that nurses' perceptions of patients' responsiveness and length of time nurses care for patients will influence nurse-patient interactions. Patterns of interaction suggest that nurses spend more time providing patients with information that the nurses consider important, rather than assessing or responding to patients' needs.

Attitude of Health Personnel↗
PubMed1987

Anury in two Cairn terriers.

Congenital anury (taillessness) was observed in 2 Cairn Terriers. Fecal staining of the hind limbs was evident in both dogs. A mating of the affected dogs produced a litter of 2 apparently normal pups. The small litter size may have been attributable to lethal gene combinations similar to those described in mice. The radiographic appearance of the caudal and sacral vertebrae was atypical in both tailless dogs. Results of myelography and electrodiagnostic testing of anal sphincter function were normal in one of the dogs. One of the tailless dogs was euthanatized and was found to lack specific muscles and muscle parts responsible for normal defecation, which resulted in fecal staining of the hind limbs. Pedigree analysis revealed the tailless dogs to be closely related and slightly inbred, suggesting a hereditary etiologic factor for anury.

Animals↗
PubMed1985

Smoking cessation among coal miners as predicted by baseline respiratory function and symptoms: a 5-year prospective study.

A prospective analysis was used to test whether respiratory impairment or the presence of respiratory symptoms predicts 5-year cigarette smoking cessation in a sample of 1,118 U.S. white, male, underground coal miners. Miners were examined in 1977 and re-examined in 1982 by NIOSH, and all miners with test abnormalities were so informed by letter. Respiratory impairment was measured by an index of airways obstruction combining the spirometric measures of Forced Vital Capacity (FVC) and Forced Expiratory Volume in 1 sec (FEV1). Bronchitis symptoms were measured by an index that combined chronic cough (3+ months/year) and chronic phlegm (3 + months/year). Among these coal miners, the presence of chronic respiratory symptoms initially was inversely associated with cigarette smoking cessation. Respiratory impairment, however, was positively associated with cigarette smoking cessation but did not reach statistical significance.

Bronchitis↗
PubMed1977

Behavioral factors and denture status.

The experiences and impressions for most of the 64 patients who entered the project in 1968 reveal that the opportunity to obtain new dentures, prepared according to the best available technology by highly skilled dentists and dental laboratory technicians, has had an identifiable impact on each of the several behavioral variables for which changes were predicted before the study began. There has been general improvement in self-image, confidence, and relaxation, and these changes often were associated with perceived improvement in fit of dentures, ability to eat, ability to talk, and general health. Although some patients experienced serious health problems during the 6 year study period, neither were these attributed to nor did they appear associated in any way with denture status. The patient population, in general, was very cooperative. Fifty-three patients stayed with the study for 6 years. Most kept their appointments and followed the instructions and advice of their dentists on all matters but one--that of removing their dentures at night. In explaining why they did not remove their dentures at night, most of the patients gave evidence of a high degree of sexual symbolism associated with teeth and denture status.

Adult↗
PubMed1976

Geographic access to hospital care: a 30-minute travel time standard.

A review of literature focusing upon geographic accessibility to health facilities indicates that while distance has been the traditional measure, travel time may now be a more meaningful indicator. Applying a 30-minute travel time standard to general hospitals, as advocated by various health plans, this paper illustrates an approach to the determination of geographic accessibility through a combination of a travel time file and sociodemographic profiles. Focusing upon all residents of West Virginia, the study identifies the number and characteristics of persons who reside within and beyond the 30-minute standard. More than 10 per cent of the entire population and nearly 20 per cent of the rural residents live in areas which are, by this standard, inaccessible to general hospitals. The "inaccessible" populations are characterized as having sociodemographic attributes associated with high medical needs. Other applications of travel time data are discussed.

Adolescent↗
PubMedDate not supplied

Chronic respiratory effects of exposure to diesel emissions in coal mines.

A 5-yr prospective design was employed to test the hypothesis that exposure to diesel emissions leads to chronic respiratory effects among underground coal miners. Changes in respiratory function and development of chronic respiratory symptoms were measured during a 5-yr study period (i.e., 1977 to 1982) in 280 diesel-exposed and 838 control miners from Eastern and Western United States underground coal mines. Spirometry measures of respiratory function included forced expiratory volume in 1 sec (FEV1.0), forced vital capacity (FVC), and forced expiratory flow rate at 50% of FVC (FEF50). Chronic respiratory symptom measures, which included chronic cough, chronic phlegm, and breathlessness, were obtained by questionnaires, as were smoking status and occupational history. Based upon these data, the pattern of evidence did not support the hypothesis either in an age-adjusted comparison of diesel vs. nondiesel miners or in an internal analysis by cumulative years of diesel exposure.

Adult↗
PubMedDate not supplied

Pregnancy wantedness in adolescents presenting for pregnancy testing.

PURPOSE: To explore and describe dimensions of pregnancy wantedness in adolescents who present for pregnancy testing. DESIGN: Descriptive survey. METHODS: Adolescents presenting for pregnancy testing at a multiservice teen center were invited to participate by completing the Pregnancy Importance Questionnaire while awaiting the results of their pregnancy test. Eighty-nine adolescents responded to questions concerning their desire for pregnancy, knowledge and access to birth control information and supplies, and expectations of how a pregnancy would change their lives. RESULTS: Approximately 7% wanted the pregnancy test to be positive, 60% wanted it to be negative, and 33% were not sure. There was a moderately low (1.97 out of 5) desire for pregnancy, a moderately high (3.11 out of 5) knowledge of and access to birth control, and moderately low (2.08 out of 5) expected changes with a pregnancy. There were no differences in these dimensions by age group (early, middle, and late adolescence). CLINICAL IMPLICATIONS: All clinicians working with adolescents should explore sexual risk-taking and pregnancy prevention measures among these clients. Appropriate counseling and follow-up is necessary for adolescents who present for pregnancy testing, whether the pregnancy test is positive or negative.

Adolescent↗