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Biomedical subjects

D S Hungerford

Publications and source records attributed to D S Hungerford.

At least 91 records · Page 5Linked to original sources

Corrective osteotomy for osteonecrosis of the femoral head.

We reviewed the long-term results of thirty-seven corrective osteotomies that had been performed for osteonecrosis of the femoral head that was stage II or III according to the classification of Ficat and Arlet. At a mean of 11.5 years (range, five to eighteen years) postoperatively, twenty-eight hips (76 per cent) had a good or excellent result according to the Harris hip-scoring system, and nine (24 per cent) had a fair or poor result and subsequently needed a total hip arthroplasty. Six of the nine failures were in the seventeen hips of patients who had received corticosteroids. Conversely, of the twenty hips of patients who had not received corticosteroids, seventeen (85 per cent) had a good or excellent result as determined by the Harris hip score at the latest follow-up evaluation. Five of the six hips that had had a combined necrotic angle of more than 200 degrees preoperatively had subsequent collapse of the femoral head. Of the thirty-one hips that had had a combined necrotic angle of less than 200 degrees preoperatively, twenty-seven (87 per cent) had a good or excellent clinical result. There were five complications. Three non-unions and one cutout of the compression screw were successfully treated, and these hips had an excellent clinical result at the time of the latest follow-up. The fifth complication was osteomyelitis and led to a poor result. The results of this study suggest that corrective intertrochanteric osteotomy is a successful treatment for Ficat and Arlet stage-II or III disease if the patient has a small or medium lesion (a combined necrotic angle of less than 200 degrees) and is not receiving continuous high doses of corticosteroids.

Adolescent↗

The operative treatment of peroneal nerve palsy.

We retrospectively reviewed the results of operative decompression for peroneal nerve palsy in thirty-one patients who had been managed between 1980 and 1990. All patients had been managed non-operatively for at least two months after they had initially been seen. Intraoperatively, we found epineurial fibrosis and bands of fibrous tissue constricting the peroneal nerve at the level of the fibular head and at the proximal origin of the peroneus longus muscle. At a mean of thirty-six months (range, twelve to seventy-two months) postoperatively, thirty (97 per cent) of the thirty-one patients reported subjective and functional improvement and were able to discontinue the use of the ankle-foot orthosis. In contrast, only three of nine patients who had been managed non-operatively reported subjective and functional improvement (p < 0.01). Peroneal nerve palsy does not always resolve spontaneously; if it is left untreated, the loss of dorsiflexion of the ankle and persistent paresthesias can result in severe functional disability. Therefore, if non-operative measures do not lead to improvement within two months, we believe that operative decompression should be considered.

Adolescent↗

Avascular necrosis of the talus treated by core decompression.

We reviewed 11 patients (17 ankles) who had had core decompression for symptomatic avascular necrosis of the talus before collapse. The Mazur grading system was used to assess function preoperatively and at final follow-up, and radiographs were graded according to the Ficat and Arlet (1980) classification modified for the ankle. At a mean follow-up of seven years (2 to 14) 14 ankles (82%) had an excellent or good outcome (Mazur scores > 80 points; pain scores > 40 points (41 to 50). The other three ankles required tibiotalar fusion at a mean of 13 months (5 to 20) after core decompression. We conclude that core decompression is a viable method of treatment for symptomatic avascular necrosis of the talus before collapse.

Adult↗

History of the contralateral knee after primary knee arthroplasty for osteoarthritis.

Published reports of series of total knee replacements vary between 20% and 75% in the percentage of patients eventually having bilateral replacements. There are no data in the literature on the predicted course of the contralateral knee for patients presenting for total knee replacement. This study reviewed the history of the contralateral knee in patients with a diagnosis of osteoarthritis presenting for unilateral primary total knee arthroplasty. The current study group comprised 185 patients who had either a minimum 5 year followup (range 5-12.5 years) or who were known to have had a second knee arthroplasty before 5 years. Evaluation included a full clinical and radiographic examination of the contralateral knee at index arthroplasty and at final followup. Of the 185 patients, the contralateral side initially was asymptomatic in 36%, mildly symptomatic in 16%, moderately symptomatic in 28%, and severely symptomatic in 20%. Seventy-nine (43%) knees eventually underwent contralateral arthroplasty. Ninety-three percent of patients who had moderate or severe symptoms and severe radiographic arthritis of the contralateral side at the time of presentation later underwent total knee replacement. However, patients who presented initially with mild symptoms or who had no symptoms had only a 9% incidence of knee arthroplasty.

Adult↗

Radiographic characterization of aseptically loosened cementless total knee replacement.

From January 1980 to December 1992, 655 cementless total knee arthroplasties with the PCA total knee system were done at the authors' institution. Thirty of these knees have been revised for aseptic loosening of either tibial or femoral components or both. Patients in the failed arthroplasty group were matched directly to a control group with well-functioning, stable and painless cementless total knee prostheses (Knee Society objective score, > 90 points). In this study, the authors analyzed any alignment differences between the 2 groups of knees. Special attention was given to the postoperative radiographs to evaluate for potential predictors of success versus failure. Multiple radiographic parameters were measured for each knee and included measures of frontal alignment, sagittal alignment, rotation, percent prosthetic coverage, and cortical thickness (denoted as the cortical-cancellous index). On univariate analysis, no individual radiographic parameter was significantly different in the failure group versus the control group. However, multivariate analysis indicated that certain combinations of abnormal parameters were significantly higher in the failed group than the control group. These parameters included measures of frontal and sagittal plane component alignment. The summated abnormal parameters per patient averaged 3.67 (range, 1-7) for the failure group and 1.80 (range, 0-7) for the control group.

Activities of Daily Living↗

Revision and primary hip and knee arthroplasty. A cost analysis.

The cost of health care in the United States has been rising steadily during the past 10 years. Total joint arthroplasty, a commonly performed orthopaedic procedure, accounts for approximately $10 billion dollars per year. The objective of this study was to perform a clinician-oriented cost analysis of primary and revision hip and knee arthroplasty. Twenty-five consecutive cases each of total knee arthroplasty, total hip arthroplasty, revision total knee arthroplasty, and revision total hip arthroplasty were analyzed. The length of stay and number of minutes spent in the operating room were significantly higher for the patients with revision hip surgery than for the other groups. The total charges for the prosthesis in the 4 groups exceeded 40% of the total charges for the procedure. Primary hip and knee surgery had similar billed costs, and work for revision hip surgery has a significantly higher billed cost than physician's work. The implant selection process by an orthopaedic surgeon performing arthroplasty of the hip and knee needs to include economic aspects.

Costs and Cost Analysis↗

Partial denervation for persistent neuroma pain after total knee arthroplasty.

Despite the high percentage of patients who are satisfied completely with the results of total knee arthroplasty, there is a small group who remain disabled because of persistent neuroma pain. Recently, a better understanding of the innervation of the skin and capsule around the human knee joint has provided a theoretical basis for denervation in this group of patients. Fifteen patients were identified who had persistent or worse knee pain for > 6 months after total knee arthroplasty. In each patient, component loosening, malalignment, knee instability, and infection had been excluded systematically as a source of pain. Pain was evaluated preoperatively with the Knee Society Functional Score Questionnaire and a visual analog scale. To be selected for surgery, each patient must have had a reduction by 5 points on the visual analogue scale for pain after undergoing selective nerve blocks. Postoperative assessment was done by a team that did not include the surgeon who did the denervation. The technique for selective knee denervation is described in detail. All 15 patients had at least 1 of the nerves to the knee selectively denervated (45 nerves in 15 patients). All patients reported subjective improvement in the immediate postoperative period. This improvement was maintained at a mean followup of 12 months (range, 6-16 months). Selective knee denervation is indicated in the management of intractable knee pain of neuroma origin after total knee arthroplasty.

Aged↗

Total knee arthroplasty in the very aged.

Twenty-six total knee arthroplasties were performed on 20 patients who were 85 years or older (mean, 87 years). Only those patients with a minimum of 3 years' followup are reported here. One patient died approximately 1 year after surgery, and 4 patients (5 knees) were lost to followup, leaving 20 total knee arthroplasties in 15 patients to be reported. Postoperative results were based on a 100-point scoring system that is a modification of the Knee Society scoring system. Eleven knees received an excellent rating, 4 good, 2 fair, and 3 poor. The primary indication for surgery in this patient population was pain control. Most patients required the continued use of ambulatory assistive devices such as a cane after surgery, but pain relief was good or excellent in 19 of 20 knees and quality of life improved. All patients tolerated the procedure well, with few postoperative complications noted. There was no perioperative mortality, and all wounds healed normally. Total knee arthroplasty is a safe and reliable procedure in the very aged patient for management of pain and deformity secondary to arthritis of the knee.

Aged↗

Long-term results of core decompression for ischaemic necrosis of the femoral head.

We have studied the long-term results of core decompression as the sole treatment for Ficat stages I, II and III ischaemic necrosis of 128 femoral heads in 90 patients. The 5-, 10- and 15-year survival rates for the three stages were respectively: stage I 100%, 96% and 90%; stage II 85%, 74% and 66%; and stage III 58%, 35% and 23%. At a mean follow-up of 11 years (4.5 to 19), 55 hips had failed (43%). No further surgery had been needed for 88% of stage-I, 72% of stage-II and 26% of stage-III hips; but despite the generally satisfactory clinical results, 56% of the hips had progressed radiographically by at least one Ficat stage. Complications of the core procedure included four fractures, all from postoperative falls, and one head perforation due to technical error. We conclude that core decompression delays the need for total hip replacement in young patients with ischaemic necrosis.

Adolescent↗

The treatment of osteoarthritis of the knee with pulsed electrical stimulation.

OBJECTIVE: The safety and effectiveness of pulsed electrical stimulation was evaluated for the treatment of osteoarthritis (OA) of the knee. METHODS: A multicenter, double blind, randomized, placebo controlled trial that enrolled 78 patients with OA of the knee incorporated 3 primary efficacy variables of patients' pain, patients' function, and physician global evaluation of patients' condition, and 6 secondary variables that included duration of morning stiffness, range of motion, knee tenderness, joint swelling, joint circumference, and walking time. Measurements were recorded at baseline and during the 4 week treatment period. RESULTS: Patients treated with the active devices showed significantly greater improvement than the placebo group for all primary efficacy variables in comparisons of mean change from baseline to the end of treatment (p < 0.05). Improvement of > or = 50% from baseline was demonstrated in at least one primary efficacy variable in 50% of the active device group, in 2 variables in 32%, and in all 3 variables in 24%. In the placebo group improvement of > or = 50% occurred in 36% for one, 6% for 2, and 6% for 3 variables. Mean morning stiffness decreased 20 min in the active device group and increased 2 min in the placebo group (p < 0.05). No statistically significant differences were observed for tenderness, swelling, or walking time. CONCLUSION: The improvements in clinical measures for pain and function found in this study suggest that pulsed electrical stimulation is effective for treating OA of the knee. Studies for longterm effects are warranted.

Adult↗

Total knee arthroplasty in diabetic patients. Comparison to a matched control group.

Between January 1980 and July 1989, 63 total knee arthroplasties were performed on 48 patients who had a clinical history of diabetes mellitus. Six patients died prior to completing the 2-year follow-up period and two patients (3 knees) were lost, leaving 53 knees in 40 patients available for review. The patients were considered as a total group, and were also divided into two subgroups: (1) insulin-dependent diabetes mellitus (IDDM) (9 knees) and (2) noninsulin-dependent diabetes mellitus (NIDDM) (44 knees). There were 10 men and 30 women in the series with an average age of 67. Patients were followed from 24 to 126 months (average, 54 months). The Porous Coated Anatomic total knee system (Howmedica, Rutherford, NJ) was used without cement in 30 knees and with cement in 23 knees. Diabetic patients were matched to a nondiabetic control group using a computer-generated selection process to match the following parameters: (1) age at surgery, (2) sex, (3) arthritic diagnosis, (4) length of follow-up period, (5) mode of fixation, and (6) preoperative deformity. Statistical analysis was performed using regression analysis and chi-square tests. In the diabetic group, there was an average clinical score of 85, with 43 knees (82%) rated excellent or good. Ten knees (18%) were rated fair, poor, or required revision (4 revisions, 7%). This was statistically different from the control group, which had an average clinical score of 92, with 51 knees (96%) rated excellent or good, 1 fair rating, and 1 revision (P < .001).(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗