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Biomedical subjects

D S Kalra

Publications and source records attributed to D S Kalra.

At least 19 recordsLinked to original sources
PubMed1981

Thymus derived rosette forming cell counts and lymphocyte response to phytohaemagglutinin in animals affected with squamous cell carcinoma of horn.

A non-immune erythrocyte rosette test was used to examine the levels of thymus derived lymphocytes in the peripheral blood of 12 bovine horn cancer patients and an equal number of age-matched unaffected controls. The proportion of rosette forming cells (RFC) in horn cancer affected animals was found to be approximately half that of unaffected controls. Phytohaemagglutinin was used to examine lymphocyte transformation (LT), in vitro, of lymphocytes from the peripheral blood of six horn cancer affected animals as well as unaffected controls. Transformation values in affected animals were found to be much lower than in age-matched controls. Lower values of RFC as well as LT in the horn cancer affected animals compared with unaffected controls are suggestive of depression of cell mediated immunity in this condition.

Animals↗
PubMed1979

Antigenic similarity between squamous cell carcinoma of horn (horn cancer) and normal bovine foetal tissues.

Normal bovine foetal (liver and skin) and horn cancer tissue antigens were examined using double diffusion agar gel precipitation and immuno-electrophoretic tests to detect any cross reactivity among them. Rabbit horn cancer antisera absorbed with normal bovine liver, skin and horn core epithelium antigens, when tested with foetal skin and liver (4 to 6 months of gestation), revealed the presence of 2 foetal antigens in horn cancer. Immuno-chemically 2 of the horn cancer antigens were found to be identical to the bovine foetal antigens.

Animals↗
PubMed1977

Fusarium equiseti associated mycotoxins as possible cause of Degnala disease.

In an attempt to find out the etiology of Degnala disease, occurring among buffaloes and zebu cattle in certain rice growing areas of India, preliminary field and laboratory investigations were conducted. On the basis of information so obtained, certain hypotheses (possible causes) were formulated and each of them was examined by instituting laboratory and experimental studies. These investigations suggested the possibility of the involvement of mycotoxins.

Animals↗
PubMed1977

Pathology of Degnala disease in cattle and buffaloes.

Degnala disease, which is believed to be a mycotoxicosis, has clinical syndrome similar to chronic ergotism and is characterised by development of oedema, necrosis and gangrene of the legs, tail, ears, etc. The gross and histopathologic studies revealed thickening of the wall of blood vessels, associated with thrombus formation, and eosinophilic infiltration in the subcutaneous connective tissue of the affected parts of the body.

Animals↗