Biomedical subjects

D S McCraw

Publications and source records attributed to D S McCraw.

2 recordsLinked to original sources

PubMed1986

A case-control study of leukemia at an oil refinery.

A previous retrospective follow-up mortality study of white men employed at an oil refinery found an excess of leukemia deaths, especially of acute myeloid leukemia (AML). A case-control study was done to determine if the excess could be related to any particular jobs or departments at the refinery or to benzene exposures. The study includes 14 cases with leukemia (eight cases with AML) and 50 matched controls. No particular job or department was identified as the likely source of the excess leukemia deaths. Furthermore, the cases apparently had not been exposed to more benzene than had the controls. Thus, the reason for the excess leukemia at this refinery was not identified. The limitations of the study are discussed.

Benzene↗

PubMed1985

Excess leukemia in a refinery population.

A retrospective follow-up mortality study of white male employees of an oil refinery located in southern illinois revealed a statistically significant excess number of deaths due to leukemia compared with the experience of U.S. white males (standardized mortality ratio [SMR] = 213; 95% confidence interval [Cl], 117 to 358). The excess was due mainly to acute myeloid leukemia (AML) (SMR = 394; 95% Cl, 172 to 788). From 1973 to 1982, fourteen leukemia deaths were identified; eight of the cancers were of the AML cell type. The work histories of the decedents were examined for the potential for benzene exposure. Although specificity of the work histories was limited, the investigation has shown that the subjects did not work in jobs identified as having the highest benzene exposures. At this time, the excess leukemia remains unexplained.

Chemical Industry↗