PubMed HealthSearch

Biomedical subjects

D S Nicholls

Publications and source records attributed to D S Nicholls.

9 recordsLinked to original sources

Oedemerid blister beetle dermatosis: a review.

Blister beetle dermatosis is a distinctive vesiculobullous eruption that occurs after contact with three major groups of beetles (Order: Coleoptera). It is caused by a vesicant chemical contained in the body fluids of the beetles. The smallest and least known family is the Oedemeridae. Although there are few references in the medical literature, blister beetle dermatosis caused by oedemerids may be more common and widespread than currently recognized. The best known family is the Meloidae with numerous species worldwide causing blistering. The vesicant chemical in both Oedemeridae and Meloidae is cantharidin. The third group of blister beetles includes species of the genus Paederus (Family: Staphylinidae). The clinicopathologic picture differs because this genus contains a different vesicant agent, pederin. The clinicopathologic features of oedemerid blister beetle dermatosis are described. The world medical and relevant entomologic literature is reviewed.

Animals

Sunbed-induced pseudoporphyria.

The clinical details of four fair-skinned women with recurrent blistering and skin fragility are presented. All had considerable sun-exposure and had used sunbeds for years. Specific causes of bullous dermatoses including drug ingestion, porphyria, cutaneous amyloidosis and epidermolysis bullosa acquisita were excluded. Long-term recurrent exposure to high doses of sunbed radiation in chronically sun-damaged skin appears to be a further cause of pseudoporphyria.

Adult

Cutis marmorata telangiectatica congenita with soft-tissue herniations on the lower legs.

Cutis marmorata telangiectatica congenita is a rare vascular anomaly, producing a flat or depressed reticular erythema of variable extent, giving rise to a marbled effect. There is a predilection for females, and there is a frequent association with other congenital anomalies, of which a large number and variety have been described. A female neonate is reported with cutis marmorata telangiectatica congenita and two associated soft-tissue lesions on the anterior lower legs, which developed several weeks after birth. We believe these lesions, which have not been previously described, to be soft-tissue herniations with surrounding subcutaneous tissue atrophy.

Atrophy

Onychomycosis caused by Trichophyton equinum.

A case of onychomycosis caused by Trichophyton equinum affecting the right thumbnail of a 13-year-old girl is described. Trichophyton equinum appears to be an extremely rare cause of nail infection.

Adolescent

Halo dermatitis around a melanocytic naevus: Meyerson's naevus.

A case of halo dermatitis (eczema) around a pigmented naevus is reported. This appears to be a not uncommon condition which is not described in major dermatology textbooks. The relevant literature is reviewed, and the eponym 'Meyerson's naevus' is suggested.

Adult