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Biomedical subjects

D Saah

Publications and source records attributed to D Saah.

At least 19 recordsLinked to original sources
PubMed1997

Hemangioendothelioma of the temporal bone in a child.

Hemangioendothelioma is a vascular tumor of endothelial cell origin. It may involve bone or soft tissues and can behave like a benign or a malignant tumor. In the literature there are several case reports on the involvement of the head and neck region, but only three cases of temporal bone involvement, all of them in adults. A 3-year-old child, complaining of left retro-auricular swelling and tenderness, was found to be suffering from hemangioendothelioma of the temporal bone. Doppler ultrasound and CT scan showed a highly vascular mass with bone destruction. Wide surgical excision was recommended, but rejected by the parents, nor did they agree to treatment with alpha-interferon. The child did not return for any further treatment.

Child, Preschool↗
PubMed1996

[An unusual bronchial foreign body: a fragment of a tracheostomy tube].

A fragment of a fractured tracheostomy tube as a foreign body in the bronchus is very unusual. We report an 18-year old male with Hunter's syndrome who presented with fever and bronchorrhea. He had worn a tracheostomy tube for 2 years without its being removed for cleaning. Chest X-ray showed an opaque foreign body in the right main bronchus which was removed through a flexible bronchoscope and found to be a piece of the broken edge of the outer cannula of a tracheostomy tube. We suggest regular examination of tracheostomy tubes for signs of wear-and-tear and recommend their periodic renewal before they become worn out.

Adolescent↗
PubMed1996

Parapharyngeal abscess in children: the role of CT for diagnosis and treatment.

Parapharyngeal abscess (PPA) in children is an uncommon deep neck space infection. Computerized tomography (CT) is an important diagnostic aid. However, CT scan is not specific in differentiating an abscess from cellulitis or inflammatory edema. A retrospective review of eight children with a CT diagnosis of PPA was undertaken. In three patients an abscess was surgically confirmed. In two patients surgical exploration did not reveal an abscess and in three the infection resolved with intravenous antibiotic therapy only. Although CT is a useful diagnostic tool for PPA, surgical intervention should be based mainly on the clinical status of the patient and the non-responsiveness to i.v. antibiotic therapy.

Anti-Bacterial Agents↗
PubMed1996

Mucosal melanoma following autologous stem cell transplantation for non-Hodgkin's lymphoma (NHL).

The incidence of secondary malignancy following autologous stem cell transplantation (ASCT) is increasing. We describe a patient with stage IVB Hodgkin's disease who developed primary amelanotic malignant melanoma of the tongue 18 months following autologous stem cell transplantation. She was treated by partial glossectomy and supra-omohyoid neck dissection followed by cytokine-mediated immunotherapy. Malignant melanoma of the skin is a frequent secondary solid tumor seen in patients undergoing stem cell transplantation. However, mucosal melanoma which is rare by itself (0.2-8%) has never been reported in NHL patients following ASCT. Early diagnosis and initiation of combined local and systemic treatments including immuno-therapy may improve the outcome of this rare but lethal complication.

Adult↗
PubMed1994

Rhinocerebral aspergillosis in patients undergoing bone marrow transplantation.

Rhinocerebral aspergillosis (RA) is becoming increasingly common in patients undergoing bone marrow transplantation (BMT). The disease can involve nearly all major head and neck structures, including the nose, paranasal sinuses, and orbits. Intracranial extension of the infection is of major concern, since this is usually a fatal complication. Our study population comprised 423 consecutive BMT patients at Hadassah University Hospital from January 1986 to August 1992. Eight patients (1.9%) developed RA, 5 of whom had underlying hematologic malignancies, and 3 of whom had severe aplastic anemia. Only 2 of the 8 patients responded completely to therapy, with a follow-up of 15 months. It appears that RA is a fatal complication in immunocompromised patients post-BMT. Early diagnosis followed by extensive surgical debridement of necrotic tissue and systemic, as well as topical, antifungal therapy with amphotericin B or its new formulations and the patient's recovery of bone marrow function may improve the outcome of this life-threatening complication.

Adolescent↗
PubMed1994

Aural myiasis caused by flesh fly larva, Sarcophaga haemorrhoidalis.

During the years 1990 to 1993, four cases of aural myiasis in children, caused by the flesh fly larvae of Sarcophaga haemorrhoidalis, are reported. The patients were admitted to the Emergency Room complaining of discharging ear, otalgia, and itching. Flesh fly larvae were removed after local treatment and identified as Sarcophaga haemorrhoidalis. These cases are discussed with a review of the literature.

Animals↗
PubMed1993

Traumatic macroglossia.

A case of severe macroglossia resulting from trauma (tongue biting) during eclampsia and causing respiratory obstruction is described. Despite medical treatment with steroids and antibiotics for a week, followed by tracheostomy, no significant improvement was observed. After an energetic but cautious maneuver of reducing and restraining the tongue in the oral cavity, the swelling reduced dramatically in 24 to 48 hours. Earlier manual replacement of the tongue into the oral cavity is advised in order to arrest the cycle of venous and lymphatic obstruction and congestion that leads to further edema and increased tongue swelling. The mechanism of traumatic macroglossia is discussed.

Adult↗