Approaching the MCQ component.
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Biomedical subjects
Publications and source records attributed to D Sales.
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To define the role of bowel rest as an independent variable from nutritional support a prospective, randomised controlled trial was undertaken in 51 patients with active Crohn's disease unresponsive to other medical management. Nutritional support for 21 days was randomised to total parenteral nutrition and nil by mouth (n = 17), defined formula diet administered through a nasogastric tube (n = 19), or partial parenteral nutrition and oral food (n = 15). Nutrient input in the first two groups provided 40 non-protein kcal/kg ideal body weight /d and 1g/ kg/d protein respectively, while the third group received 15 non-protein kcal/kg/d and 0.3 g/kg/d protein intravenously and ate unrestricted food. Clinical remissions occurred in 71% of patients on parenteral nutrition, in 58% on the defined formula diet and in 60% on partial parenteral nutrition; the probability for each group of being in remission at one year, after successful therapy was 42%, 55%, and 56% respectively. These differences were not significant. In patients with active Crohn's disease bowel rest was not a major factor in achieving a remission during nutritional support and did not influence outcome during one year's follow-up.
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This paper reports and discusses a laboratory experiment that tested the anaerobic fluidized bed (AFB) technology as a means for the treatment of concentrated industrial wastewater (wine distillery, vinasses) at thermophilic conditions. The purposes were to operate and characterize AFB under high organic loading conditions and to report on their steady-state performance. Experimentally, it was confirmed that AFB systems can achieve > 82.5% chemical oxygen demand (COD) reduction at a COD loading of 32.3 kg of COD m-3 day-1 for treating vinasses of wine. At hydraulic retention time (HRT) of 0.46 day, the volumetric rate of methane generation was 5.8 m3 of CH4 m-3 day-1 with a methane yield of 0.33 m3 of CH4/kg of COD removal. The greatest efficiency of substrate removal was 97% for an organic loading rate of 5.9 kg of COD m-3 day-1 and HRT of 2.5 days. The food-to-microorganism (F:M) ratio can be used as a parameter for treatment performance evaluation of AFB. For vinasses, excellent COD reduction and methane production were achievable at the F:M ratio of 0.55 kg of COD kg-1 VSatt day-1 (more than 80% of feed COD was removed, and 9 m3 m-3 day-1 of methane was produced).