Simple, rapid method for assay of aminoglycoside antibiotics.
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Biomedical subjects
Publications and source records attributed to D Samson.
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To test different hypotheses about age-related slowing of word and picture naming, response latencies of young and older adults were compared in 2 experiments using the same 4 tasks: picture naming, written word pronunciation, and picture and word categorization. In each case, the target word or picture was presented with a distractor word that had to be ignored. Analyses showed the expected main effects of age, modality, and interference conditions but no consistent interaction between age and other factors. More particularly, age-related slowing was similar in word and picture processing and interference was proportional to overall speed of responding. Thus, no support was found for the hypotheses assuming either declining inhibitory mechanisms or task-specific deficits in older adults. These results were discussed in relation to characteristics of the experimental tasks.
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Urine samples for assay, temperature, heart rate, and blood pressure were collected daily at 2-h intervals from 11 consenting subjects undergoing abdominal surgery, as well as 10 age-and sex-matched control subjects. Alterations in level, and timing of circadian excretion of catecholamine metabolites, adrenal cortical hormones, sodium, potassium, creatinine, and vital signs following surgery were measured. Data were examined to determine if a relationship exists between the degree of circadian alteration and the subject's return to typical circadian profiles. The data suggest that certain circadian rhythms of hospitalized subjects were altered and uncoupled from external stimuli. In addition, subjects with less disruption in some variables following surgery regained rhythmicity more quickly than more disrupted subjects. These findings suggest that health professionals should individualize patient care to promote rhythmicity. In addition, patient assessment should consider individual circadian patterns and disruption following surgery.
Alterations in level, timing, and coupling of circadian excretion of catecholamine metabolites, adrenal cortical hormones, sodium, potassium, creatinine, and vital signs in acute-care surgical patients were measured. Data were examined to determine if a relationship exists between the degree of circadian alteration and the subject's reentrainment to typical circadian profiles. Urine samples for assay, temperature, heart rate, and blood pressure were collected daily at 2-hour intervals from 11 consenting surgery subjects and 10 age- and sex-matched control subjects. The data indicate that certain circadian rhythms of hospitalized subjects were altered and uncoupled from external stimuli. These findings suggest that nurses (1) give individualized patient care to promote reentrainment recovery; and (2) refine nursing assessment to consider individual circadian patterns.