[Proceedings: Radiotherapy of malpighian cancers of the anus. Epidermoid cancers of the anus].
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Biomedical subjects
Publications and source records attributed to D Sarrazin.
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A total of 655 patients were investigated by both mammography and contact thermography, and 63 cancers of the breast were detected. Thermography was slightly more sensitive (0.82) than mammography (0.75). They were of equal specificity (0.96 and 0.97). A critical analysis of the experimental conditions, however, leads the authors to propose thermography as the essential investigation completing clinical examination and mammography. It may also have a certain prognostic value, but this remains to be demonstrated.
Without prior treatment, 13 children with stage IV Hodgkin's disease have received a multiple drug therapy (MOPP). Of these patients, 7 have experienced a complete remission; 3 a partial remission, completed in two cases by radiotherapy on the site of the residual disease, and the third by another combination chemotherapy. Out of the 10 children living as of July 1st 1975, 8 are still on first remission. Tolerance for the treatment has been good. The evolution of the disease and problems of treatment are also discussed.
Non Hodgkin Lymphomas are in children nostly diffuse and non or poorly differentiated. The exact frontiers with ALL are difficult to assess. With old classical treatments, the chances of cure were limited to localized tumors (stage I). The present indications of combined intensive chemotherapies, of neuromeningeal prophylaxis, and radiotherpy are analyzed. Preliminary results in 51 children treated first in 1973-1974 are presented. The rate of complete remission is 82%. Actuarial survival rate is 57% at 30 months. The aim and the limitations of treatment protocol are discussed.
Malignant neoplasia of head and neck in children are mostly embryonal sarcoma and non Hodkgin's lymphomata. Squamous-sell carcinomas are only 10%. The main locations are in nasopharynx and paranasal sinuses. Symptoms are corelated with location of the primary. Treatment depends of the pathologic type. Combination of chemotherapy and radiotherapy, and sometimes surgery, yield now more cured patients, especially in embryonal sarcoma.