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Biomedical subjects

D Sarti

Publications and source records attributed to D Sarti.

At least 19 recordsLinked to original sources

Reliability of endosonography in evaluation of anal fistulae and abscesses.

OBJECTIVE: To assess the reliability of anal endosonography (AES) in the diagnosis of anal fistulae and abscesses. MATERIAL AND METHODS: 86 patients with different types of anal fistulae and abscesses were prospectively examined with a 7.0 MHz transducer. Type of anal fistulae, differentiation between simple and complex tracts, and location of their internal openings were defined. In 66 cases with permeable external opening, hydrogen peroxide solution was introduced into the fistula tract. Reliability of AES was defined after surgical treatment of all cases. RESULTS: 74 anal fistulae, including 43 transsphincteric, 11 intersphincteric, 6 suprasphincteric, 3 superficial, and 11 ano-vaginal were found on AES. 27 fistulae were complex, and 47 simple fistulae. In 10 patients a coexisting abscess was found; the remaining 12 abscesses were without any fistula. Surgery confirmed the type of anal fistula in 64 patients (86.5%), and location of internal openings in 60 cases (81.1%). All abscesses were confirmed. CONCLUSION: AES showed high accuracy in diagnosing anal fistulae and abscesses.

Abscess↗

[Diagnostic possibilities of anal endosonography in proctology. Part 1].

On the basis of literature and own experience, the usefulness of endosonographic examination with the use of axial endoprobe was presented. The first part was devoted to the description of the endosonographic anatomy of normal rectum, examination technique and its usefulness in diagnosis of anal sphincters disorders. The endosonographic examinations have been performed in Poland for many years, mainly for prostate diagnostics with the use of multiplane transducers. We present a diagnostic possibilities of axial endoprobe of high frequency equipped with hard plastic cone and water balloon.

Anal Canal↗

[Diagnostic possibilities of anal endosonography in proctology. Part II].

In the second part of the paper, we present advantages and drawbacks of transanal endosonography with the use of axial endoprobe in the diagnostics of perianal and perirectal abscesses and fistulas and also for tumours of the rectum. Typical images of the fistula nad abscess were shown. Ultrasonographic staging for the rectum malignancies was presented together with possibilities of assessment perirectal lymph nodes involvement by ultrasonography. Diagnosis of local recurrence by anal endosonography was presented and compared with other methods.

Colorectal Surgery↗

[Transanal ultrasonography for diagnosis of obstetric anal sphincter trauma].

Fecal incontinence affects up to 2% of the general population. The major cause of it is related to the birth trauma of the anal sphincters. In this paper the possibilities of transanal endosonography in the assessment of the anal canal muscles defects after deliveries were presented. Anal canal sonographic anatomy together with the technique of the examination with the use of rotating endoprobe were presented. Transanal rotating endoprobe was compared with exoanal probes for visualization of the anal canal. Ultrasonic images of internal and external anal sphincters defects were shown with specific patterns of defects allowing differentiation between morphological and neurological damages of the sphincters. Anal endosonography was compared with clinical examination, electromyography and manometry in the assessment of the integrity of the anal sphincters.

Adult↗

Linguistic development in a patient with Landau-Kleffner syndrome: a nine-year follow-up.

A longitudinal linguistic analysis of aphasic disorder in a 15-year-old boy affected by Landau-Kleffner syndrome followed since the age of 6 is reported. The phonological, morphosyntactic and lexical levels of verbal deficits have been evaluated by means of collected samples of spontaneous language and a battery of linguistic tests. The clinical course has fluctuated with improvement and worsening of aphasia and epilepsy; at the end of the follow-up the boy was seizure-free and a medium-degree disturbance in language production and comprehension was present. The results of the linguistic evaluation suggest that the aphasic disturbance was related to a deficiency in phonological decoding which leads to phonological, morphosyntactic and lexical disturbances. A temporal relationship between the electroclinical picture and the aphasia has been observed: the persistent improvement in linguistic performances took place only after the disappearance of the seizures and of the EEG epileptic anomalies during sleep.

Adolescent↗

Megacystis-microcolon-intestinal hypoperistalsis syndrome in two male siblings.

Two male sibs with severe congenital megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) are presented. Both had enlarged bladder and hydronephrosis due to reduced bladder emptying, decreased bowel motility, and malrotation of the colon. Repeated careful ultrasound examination of the urinary tract in the second sib failed to show significant bladder enlargement prior to 25 weeks' gestation, which has been considered to be a reliable prenatal diagnostic sign for MMIHS. Slight bilateral enlargement of the renal pelves was noted at 21 weeks' gestation, and this may represent the earliest prenatally-detectable observation in this disease. Although more females than males with this condition have been reported, our cases provide support for an autosomal recessive mode of inheritance with a similar recurrence risk for both sexes.

Colon↗

Heating of the scrotum by high-field-strength MR imaging.

Sterility can occur in mammals if spermatogenic tissue is acutely or chronically heated to levels equal to or greater than body temperature. High-field-strength MR imaging has been shown to elevate tissue temperatures, particularly if high levels of RF radiation are used. To determine if MR imaging above the recommended level for RF radiation is associated with heating of the scrotum, scrotal skin temperatures were measured in eight subjects immediately before and after MR imaging of the scrotum with a 1.5-T, 64-MHz MR scanner at mean whole-body average specific absorption rates ranging from 0.56 to 0.84 W/kg (mean, 0.72 W/kg). The average imaging time was 23 min. A statistically significant (p less than .01) increase in average scrotal skin temperature was associated with MR imaging (before MR imaging, 30.8 degrees C; after MR imaging, 32.3 degrees C). The largest change in temperature was 3.0 degrees C, and the highest temperature measured was 34.1 degrees C. MR imaging at relatively high specific absorption rates produced a statistically significant increase in average scrotal skin temperature. However, the recorded temperatures were below the threshold known to affect spermatogenesis in mammals.

Adult↗

Automated and hand-held breast US: effect on patient management.

Breast ultrasound (US) was performed, with either an automated or a hand-held unit or both, on 1,212 patients. Of 612 asymptomatic patients, 118 (19.3%) had solitary cysts; ten (1.6%), multiple cysts; and 29 (4.7%), benign masses; however, US depicted only one (0.2%) nonpalpable mammographically undetected carcinoma. In 513 patients with palpable masses (n = 396) and with mammographically detected masses (n = 117), US was useful in avoiding an unnecessary biopsy in 113 (22.0%), leading to aspiration of a cyst in 26 (5.1%), monitoring multiple cysts in 31 (6.0%), avoiding aspiration of a solid mass in 65 (12.7%), supporting biopsy of an equivocal solid mass in 91 (17.7%), and demonstrating a nonpalpable mammographically detected carcinoma in six (1.2%). In 224 patients with either palpable or mammographically visible masses who underwent both methods of US, the 4.5-MHz or 3.9-MHz automated unit depicted the abnormality in 119 (53.1%) and the 7.5-MHz hand-held unit, in 171 (76.3%). Of 18 cancers evaluated with both methods, all were detected with the hand-held unit and only 12 were seen with the automated unit.

Adolescent↗

Static grey-scale parathyroid ultrasonography: is high-resolution real-time technique required?

Ultrasound has been used with varying success to localise parathyroid adenomas pre-operatively. We have reviewed 61 patients with pre-operative contact-scanning grey-scale parathyroid ultrasonography and subsequent surgical exploration of all four parathyroid glands. Diagnostic accuracy was 91% considering glands examined and 63% considering patients examined. There was one false positive diagnosis. False negative diagnoses (17 adenomas and five ectopic mediastinal tumours) were mainly due to upper pole adenomas, adenomas less than 10 mm X 7 mm in size and ectopic mediastinal adenomas. Static grey-scale ultrasonography is adequate for the pre-operative localisation of parathyroid adenomas, especially when high-resolution technique is not available. In fact, the overall accuracy is comparable to the recently reported diagnostic accuracy rates with high-resolution real-time systems.

Adenoma↗

Fitting a linear relationship with confidence intervals by correlation.

The study of the empirical linear relationship between two measured variables should use correlation analysis which treats the variables symmetrically, rather than linear regression which inappropriately assumes a dependent and an independent variable. An APL computer program calculates the best fitting bivariate Gaussian distribution and plots the data with the superimposed straight line relationship and the confidence interval.

Body Constitution↗

Chromosome findings in 2,500 second trimester amniocenteses.

We have analyzed the chromosome abnormalities found in 2,500 amniocenteses for prenatal diagnosis; 1,887 (75%) were performed because the maternal age was 34 years or more. Chromosome abnormalities were detected in 1.80% of those referred for advanced maternal age, 1.2% between ages 34 and 39 years and 4.6% 40 years and over. Of these, four occurred in women who would have been 34 years at delivery (2.9%). Trisomy 21 accounted for 50% of the chromosome abnormalities; sex chromosome abnormalities, for 25%; the remaining 25% was divided equally between trisomy 18 and partial trisomies and mosaics. Unexpected translocations were found in 0.4%, of which two-thirds were balanced and identified in one parent. The accuracy was 99.6%.

Amniocentesis↗

The ultrasound spectrum of prune-belly syndrome.

The sonographic features of prune-belly syndrome are illustrated and described, corresponding to a classification based on clinical and radiographic findings. The severity of urinary tract involvement determines to which group a given patient is assigned. In group I, the kidneys are dysplastic, with no appreciable surrounding renal parenchyma. In group II, there is marked dilatation of the ureter and mild dilatation or no dilatation of the renal pelvis and calyces. In group III, the involvement is milder, ranging from the sonographic findings typical of group II to those of normal-appearing urinary tract.

Abdominal Muscles↗