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Biomedical subjects

D Savić

Publications and source records attributed to D Savić.

At least 37 records · Page 2Linked to original sources

[Evaluation of long-term prognosis in patients with whiplash syndrome].

We reviewed 50 patients who sustained whiplash injuries of the neck. The mean time of the follow-up was 3 years. Only 16% of observed cases recovered completely. Residual symptoms were severe in 38%. Pain in the neck, headache and paraesthesia were the commonest complaints. Older patients and patients with significantly restricted movements of the neck, sharp local kyphotic deformity, chronic instability and neurologic involvement had a worse prognosis.

Adult↗

[Percutaneous transluminal angioplasty of the abdominal aorta using the "kissing balloon" technic].

Percutaneous transluminal angioplasty (PTA) of the distal abdominal aorta is still rarely performed procedure. Sporadic reports come from selected institutions with extensive experience in the field of PTA. Procedure is performed using so called "kissing-balloon" technique, and may be an alternative to the surgical treatment in well selected cases. We present a 45 years old woman with intermittent claudications and infrarenal abdominal aortic stenosis, treated successfully using above mentioned technique.

Angioplasty, Balloon↗

[Treatment of post-traumatic hemarthroses of the knee and ankle in children using transcutaneous electric nerve stimulation].

TENS (transcutaneous electric nerve stimulation) was applied in 36 children with knee or ankle hemarthros. Pain was diminished after first or second treatment and completely disappeared at the end of the first or second day. Swelling usually disappeared in the interval between the third and seventh day. At the end of the treatment joint movement was significantly improved. In the control group who received only conventional conservative treatment (puncture, immobilization or inactivity, drugs) swelling and pain were still present after the seventh day and these patients needed additional physiotherapy for next seven days. We consider the TENS a method of choice in the treatment of posttraumatic hemarthros providing that treatment starts immediately after the injury and that it is continually applied during 3-5 days. The patients are advised to use crutches. It is a simple, painless method which is not combined with any additional treatment. Proteolytic ointments can increase and stimulate the therapeutic effects.

Adolescent↗

[Use of prostin E2 in the treatment of stomatitis caused by radiotherapy].

Patients undergoing chemotherapy or radiotherapy for malignancies often develop annoying inflammation of the oral mucosa as a side-effect of cytotoxic therapy. As prostaglandins are known to be cytoprotective Prostin E2 was given to 10 patients with neoplasms of the ear, nose, pharynx or larynx, or of the maxillofacial region, who received radiotherapy. The reference group was made up of five patients with the analogous diagnosis who received the conventional therapy with Hexoral sol. One patient was not administered any therapy. The patients that were given Prostin E2 did not develop either the inflammatory process or stomatitis. In the reference group the inflammatory process appeared in two patients and lesions were noticed in one patient. Excellent results, although still preliminary, pointed out that preventive local administration of Prostin E2 was superior to the conventional therapy and that accordingly, Prostin E2 should be regarded as the drug of choice.

Adult↗

Otogenic facial paralysis. A histopathological study.

The histopathological changes of the facial canal and nerve in facial paralysis due to chronic suppurative otitis madia are described in six temporal bones. Bony destruction of the facial canal was found in its tympanic segment and in its upper mastoid part in all cases, but it was particularly notable in the labyrinthine segment as well. The pathological process, cholesteatoma or granulation tissue surrounding the exposed facial nerve was inflamed in all cases. The affected facial nerve showed degenerative and inflammatory changes throughout its tympanic segment in all cases, but its mastoid segment appeared to be relatively normal. Our findings suggest that facial paralysis occurs us chronic suppurative otitis when the inflammatory process specifically involves the facial nerve trunk.

Chronic Disease↗

Cholesteatoma in the oval window niche.

The histopathological changes in the oval window niche into which a cholesteatoma is spreading are described in 14 temporal bones. Extension of the matrix into the niche was found commonly. In some cases the matrix passed from the facial canal to the promontory but failed to reach the niche. The perimatrix of the cholesteatoma was composed of inflamed and vascularized granulation tissue or fibrocystic tissue. A matrix covering the walls of the niche and the footplate of the stapes or the oval window was rarely found. It was surrounded by a thin layer of non-inflamed fibrous or fibrocystic tissue which covered the niche. Bone destruction of the superstructures of the stapes was observed in 12 of the 14 cases examined. The footplate of the stapes was partially or totally destroyed in 4 cases. Bone destruction of the tympanic portion of the facial canal adjacent to the oval window niche was present in all cases. Our present studies further suggest that surgical removal of a cholesteatoma from the niche may be difficult, even when done very carefully.

Cholesteatoma↗

The relations of the mastoid segment of the facial canal to surrounding structures in congenital middle ear malformations.

The authors investigated the relations between the mastoid segment of the facial canal and the temporomandibular joint, the posterior wall of the cavum tympani and the external wall of the mastoid process in 19 cases with congenital ear malformations and 10 cases with normal ears. A significantly reduced distance was found between the facial canal and the temporomandibular joint as well as between the facial canal and the posterior wall of the cavum tympani in the groups with malformed ears as compared to the control group with normal ears.

Cephalometry↗

Characteristics of a pathological process in the destroyed tympanic part of the facial canal in chronic otitis media with cholesteatoma.

The authors examined the histopathological characteristics at the sites of destruction of the tympanic part of the facial canal in chronic otitis media with cholesteatoma. Two types of pathological process were observed. The first is characterized by the cholesteatoma at the sites resorption and the second is characterized by pronounced granulation or fibrocystic tissue.

Bone Resorption↗

[Oncocytoma of the nose and ethmoidal and sphenoidal sinuses].

The authors present a patients with oncocytoma, a rare tumor of the nasal cavity and the ethmoidal and sphenoidal sinuses. By using computerised tomography (CT) they localised the tumor and through pathohistological analysis confirmed the nature of the disease. Recurring tumors can also be localised by use of CT.

Adenoma↗

[Variations of the position of the stapes in the fossula of the round window and their surgical value].

The authors studied variations of the position of stapes in the fossula of ovale window on 300 preparations of temporal bones, under operating microscope. They noted three possible positions of the stapes: most commonly downwards to the promontorium (76%), much less frequently (15%) towards the bottom of the fossula, and rarely upwards to the facial canal (9%). Knowledge of these anatomic variations is of great importance in surgical procedures performed in this region.

Adult↗

Anatomical characteristics of the fossula fenestrae vestibuli.

Anatomical characteristics of the fossula fenestrae vestibuli were tested and analysed precisely on 200 samples of temporal bones. The fossula is usually ovoid and shallow but can be, exceptionally, elongated, narrow and deep. It is surrounded by four walls. In 45.5 per cent of cases the upper wall is formed only by the facial canal and in 54.5 per cent of cases a bony lamella is found beneath the facial canal; the promontory forms the lower wall; the front wall is formed by the bony lamella and part of the processus cochleariformis; the back wall is clearly defined in only 22.8 per cent of cases and is formed by the bony lamella of the medial wall of the tympanic cavity. In 13.2 per cent of cases the floor of the fossula partially covers the prominence of the facial canal and in two per cent the eminentia pyramidalis. Bony recesses in this region occur fairly frequently: sinus subfacialis in 60 per cent, sinus retrofenestralis in 77.2 per cent, and sinus subrostralis in 25 per cent of the cases. These anatomical variations can influence the result of surgical intervention.

Female↗

The value of computerized tomography (CT) in the evaluation of the anatomic structure of the attic.

By the use of computerized tomography (CT) the authors have examined and precisely defined the radiological anatomical characteristics of the attic and its relation to other structures of the middle and inner ear. The identification of individual morphological structures has been made on axial, semi-axial and frontal CT sections. Each type of original CT section has been compared with the corresponding original anatomical section.

Ear Diseases↗