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Biomedical subjects

D Sengupta

Publications and source records attributed to D Sengupta.

At least 55 records · Page 3Linked to original sources
PubMed1989

Effects of aspirin and paracetamol on ATPases of human fetal brain: an in vitro study.

In vitro effects of aspirin and paracetamol at the doses 200, 400, 600, 800 nmole/mg protein on ATPases activity were studied in the cerebrum and cerebellum of human fetus covering the age range from 10 weeks to 32 weeks of gestation. Both aspirin and paracetamol inhibit Na+K+ ATPase and Mg2+ ATPase in a dose dependent manner. The inhibition of Na+K+ ATPase and Mg2+ ATPase activity which may affect the release and uptake of biogenic amines in CNS, hinders the maturation of human fetal brain.

Acetaminophen↗
PubMed1989

Age-related changes of glycogen metabolism in human fetal heart.

The changes in the activities of three important glycogen metabolising enzymes, viz. glycogen synthetase, glycogen phosphorylase and alpha-D-glucosidase, along with glycogen content have been measured in adult human heart and human fetal heart collected at 13-36 weeks of gestation. At an early period, particularly 13-16 weeks of gestational age, the activity of glycogen synthetase and glycogen content were found to be maximum. However the activity of glycogen phosphorylase remained constant throughout the gestation and that of alpha-D-glucosidase showed a peak at 25-28 weeks of gestation, thereby indicating that fetal heart tissue has the capacity to utilise glycogen for energy.

Adult↗
PubMed1987

Identification of propellants of small arms ammunition.

Existing methods seem inadequate to identify propellants of small arms ammunition. The present article describes that viscosity may be effectively used to differentiate and identify those. The temperature dependence, intra- and inter-batch variation and storage effect of propellants were studied.

Firearms↗
PubMed1985

Nucleotide sequence of a major class-III phage-T3 RNA-polymerase promoter located at 98.0% of phage-T3 genetic map.

The entire nucleotide sequence of a 409-bp HincII fragment, located within the MboI-E fragment on bacteriophage T3 DNA and containing a major class-III T3 RNA polymerase promoter positioned at 98% on the standard T3 genetic map, has been determined. Alignment of this class-III promoter with previously determined T3 RNA polymerase promoters, with start points of transcription (+1) in register, indicates high degree of sequence conservation between position -16 to +6 among all T3 RNA polymerase promoters. The conserved portion of the (-) strand sequence is 5'-A-TA-T-AT-A-C-C-C-T-C-A-C-T-A-A-A-G-G-G-A---3'. This fragment also contains an open reading frame (ORF) with a translational start codon located at position +146 which is preceded by a potential ribosome binding site (RBS). There is more than 70% amino acid-sequence homology between the deduced sequences of the -NH2 terminal region of this putative T3 phage protein and the corresponding protein coded by bacteriophage T7 (protein of T7 gene 19.5).

Base Sequence↗
PubMed1981

Monoamine oxidase: studies of normal and psychiatric populations in a tropical environment.

The pattern of changes in the platelet and plasma monoamine oxidase (MAO) activities with different substrates was recorded in 75 psychiatric patients compared with 27 normal controls. The results confirm that chronic schizophrenics, manics and manic-depressives have significantly lower platelet MAO activity, while depressives show higher platelet MAO activity than controls, without affecting plasma MAO activity. No significant substrate-related differences were observed, except when tyramine was used as substrate; then acute schizophrenics showed significantly lower platelet MAO activity. The differences persist even during the treatment period. The present finding is consistent with the results previously reported and indicates that biochemically there exist no striking differences between our population and the populations reported on elsewhere in different environments.

Adult↗