Biomedical subjects
Publications and source records attributed to D Shenoy.
The relationship of the neurological manifestations to the lupus disease process is not always clear. We present a case of systemic lupus erythematosus (SLE) with subacute onset muscle weakness, which was due to polyradiculopathy, a rarely described neurological manifestation of SLE.
AIM: To study the seasonal variation in the incidence of hyponatremia and to correlate it with the rainfall pattern. METHOD: Retrospective analysis of patients having serum sodium of less than 120 meq/L was done during the 24 months from March, 1995. Patients with fever, renal failure, cardiac failure, cirrhosis, hyperlipidemia, hyperproteinemia, patients taking diuretics and postoperative patients were also excluded. Average inpatient number and rainfall for each month was noted. Daily incidence of hyponatremia was expressed as percentage of total inpatients for each day and was compared with the rainfall. RESULTS: A total of 353 patients had hyponatremia during the two years from March, 1995; 174 cases during the first year and 179 during the second year. Average inpatient strength was 302.17 +/- 21.41 during the first year and 313.67 +/- 12.94 during the next year. The incidence of hyponatremia was 0.24 +/- 0.096% between June and August and 0.1 +/- 0.04% between December and February (95% confidence interval 0.045-0.235, p < 0.01). Statistically significant correlation was observed between rainfall pattern and hyponatremia, r = 0.711, 95% confidence interval 0.478-0.913, p = 0.01 during 95-96 and r = 0.825, 95% confidence interval 0.478-0.949, p < 0.001, during 96-97. CONCLUSION: Incidence of hyponatremia is higher during the peak southwest monsoon season with similar pattern for the study period of two years. Humidity and temperature may have important role in the manifestation of hyponatremia.
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Blood sugar profile was studied by checking multiple plasma venous samples at 1/2 hr interval after porcine plain insulin. Mean blood sugar was the highest (198.8 +/- 24.6 mg%) at 1 1/2 hrs and the lowest (86.3 +/- 18.4) at 4 1/2 hrs after breakfast. 52% of the patients had hypoglycemias between 4 and 5 hrs. It is recommended that pre-lunch blood sugar be checked in those receiving plain insulin.
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Dielectric relaxation spectroscopy is used to study the relaxation processes in a nematic monomer and the corresponding cross-linked polymer nematic liquid crystal (elastomer). In the frequency window 10 mHz to 2 GHz the monomer liquid crystal shows a single relaxation whereas the polymer exhibits three relaxation processes, two of which are quantitatively analyzed. The temperature dependence of relaxation times in both the monomer and polymer follows a Vogel-Fulcher behavior. The relaxation processes are identified with specific molecular motions and activation energies are calculated in a linear approximation for comparison with literature data.
Pattern of classification in an renal neoplasm is variable. If calcium is located nonperipherally (within the mass) it is more likely to be a renal cell carcinoma. But peripheral calcification does not rule out malignancy.
Blood pressures in the temporal artery of five normotensive subjects were recorded using a modified auscultatory setup. The setup comprised a pediatric cuff to occlude the artery and a piezoelectric contact microphone to record the Korotkoff sounds. Both the cuff and microphone were held in their respective positions with an adjustable head band. The recordings were taken under four different conditions: the subject lying supine, the subject sitting at rest, the subject sitting immediately after exercise and the subject moving the head gently. These recordings were compared with readings from the brachial artery, obtained with a commercially available automatic blood pressure measuring device. Korotkoff sounds were analyzed in the time and frequency domain. Results indicate that Korotkoff sounds in the temporal artery are much smaller in amplitude, and do not exhibit the same distinctive phases as those of the brachial artery. Despite these differences, these sounds can be used to detect blood pressures at head level. The accuracy of the readings was within +/- 10%. Successful readings were also obtained with gentle head motions, demonstrating that this setup has the potential to be developed into an ambulatory blood pressure monitoring system.