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Biomedical subjects

D Shepard

Publications and source records attributed to D Shepard.

24 records · Page 2Linked to original sources
PubMed1986

Adult elbow dislocations: mechanism of instability.

From these data it appears reasonable to advocate open repair of fracture dislocations of the elbow joint, particularly those associated with radial head fractures. In these instances improved functional results can be anticipated. In simple elbow dislocations in adults, it is possible that open repair of the medial collateral ligament will produce improved functional results. However, the data, although suggestive, are not conclusive at this time. It is our belief that the indications for surgery in elbow dislocations can be summarized as follows. Surgical intervention is indicated if spontaneous redislocation occurs, unless the arm is flexed above 90 degrees. Surgery is indicated if a spontaneous redislocation of the elbow dislocation occurs with the arm in plaster. Surgical repair of the medial collateral ligament is indicated in all instances of fracture dislocations of the elbow, particularly those associated with radial head fractures. In adult simple elbow dislocations surgical repair of the anterior oblique ligament certainly does not impair elbow function at follow-up and indeed may lead to better results.

Adult↗
PubMed1985

[The Shepard radial keratotomy method].

Over the last few years American surgeons have modified the technique of radial keratotomy in different ways. D. Shepard, of Santa Maria, California, has performed more than 1800 to these operations. Forty-three of the patients, on most of whom surgery was performed in both eyes, were studied from one week to 42.5 months postoperatively by an independent observer. The preoperative evaluation, the technique of surgery, which is performed on an outpatient basis, the complications and postoperative management, the final visual results, and refraction are discussed in detail. The overwhelming majority of the patients expressed great satisfaction with the visual outcome of the surgery in spite of undercorrection and overcorrection, long-term topical treatment, glare at night, and diurnal variations of visual acuity.

Adult↗
PubMed1984

Determination of the precise location and orientation of the Escherichia coli dnaE gene.

The minimal region required for expression of the dnaE gene of Escherichia coli has been determined relative to a detailed restriction endonuclease map. This has been accomplished by analysis of Bal 31 exonuclease-generated deletions from the termini of the E. coli DNA contained in plasmid pMWE303 , a plasmid that we have previously demonstrated to contain the dnaE gene (M. M. Welch and C. S. McHenry , J. Bacteriol . 152:351-356, 1982). The competence of these deletion-containing plasmids in expressing the alpha subunit of DNA polymerase III holoenzyme has been determined by their ability both to complement a dnaE mutant and to direct the synthesis of a complete alpha subunit. The carboxyl-terminal coding region of dnaE has been identified through the detection of partial alpha polypeptides encoded by plasmids containing deletions from one end of the gene. This approach has permitted the precise determination of both termini of the dnaE gene and the determination of the orientation of the gene within the E. coli chromosome.

Chromosome Deletion↗