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Biomedical subjects

D Silver

Publications and source records attributed to D Silver.

At least 127 records · Page 7Linked to original sources

Noninvasive determination of LeVeen shunt patency.

The LeVeen peritoneovenous shunt is being used with increasing frequency for management of intractable ascites. The question of postoperative shunt patency frequently arises. This report describes a unique, noninvasive method of assessing shunt patency using Doppler ultrasound. Four of five patients with shunts judged to be occluded by this new method had the findings substantiated by peritoneal instillation of radioisotope; the fifth patient was not studied by any other method. The evaluation with ultrasound is easily performed at operation and after operation and is reliable for assessing shunt patency.

Ascites↗

Vasospastic disorders.

Acute digital ischemia not due to thromboembolism may be the result of either a primary vasospastic disorder (Raynaud's disease, acrocyanosis, livedo reticularis) or vasospasm associated with a systemic, regional, or traumatic disorder (Raynaud's syndrome, cold injury). Raynaud's disease versus syndrome is distinguishable up to 95% of the time from clinical criteria.

Arteries↗

Bone formation by revascularized periosteal and bone grafts, compared with traditional bone grafts.

Three groups of dogs were studied to compare the bone formation obtained with traditional bone grafting techniques, and that obtained with revascularized periosteum or revascularized bone grafts--all in unstressed bone. Revascularized periosteum did not produce a significant amount of bone in this unstressed model. At 4 months the revascularized rib grafts had a slightly greater tolerance to stress at the callus site than traditional bone grafts, but the incidence of non-union was the same. We conclude that the use of revascularized bone grafts should be reserved for situations in which traditional bone grafting techniques are unlikely to be successful.

Animals↗

Negative responses of the borderline to inpatient treatment.

The intense therapeutic encirclement maneuvers possible in long-term inpatient therapy of the borderline patient frequently stimulate emotional flooding and intense negative therapeutic reactions. Such reactions have understandable precipitants: a mixture of therapeutic goals, treatment methods, and defensive structures of the patient best conceptualized within an object-relations model.

Adult↗

Heparin-induced thrombocytopenia, thrombosis, and hemorrhage.

Twenty-two patients developed significant thrombocytopenia (5,000 to 96,000/cu mm; mean, 29,000/cu mm) while receiving prophylactic or therapeutic heparin. Seventeen of them developed serious thrombohemorrhagic complications which accelerated the deaths of six and contributed to the late death of one. Cessation of heparin therapy led to an immediate remission of the thrombohemorrhagic complications and thrombocytopenia, with no patient who was not already moribund dying, once appropriate therapy had been instituted. Platelet-count monitoring is recommended for all patients receiving heparin for more than 6 days, with cessation of heparin therapy mandatory for the successful management of patients with this disorder. Evidence is presented for an immunologic etiology for this disorder.

Adult↗

Peritoneal mesotheliomas.

Eight cases of peritoneal mesothelioma have been seen at the University of Missouri Medical Center and affiliated hospitals since 1940. The incidence for our patient population is 0.24 cases per 100,000 patients. The nonspecific symptoms, physical findings, x-rays, and laboratory results usually preclude an early establishment of the diagnosis. The diagnosis was eventually established at laparotomy in seven cases and at autopsy in one. Only the benign mesothelioma was resectable; that patient is doing well 10 months after operation. The survival interval of the patients with malignant peritoneal mesotheliomas averaged 3 months, with the two patients who received chemotherapy surviving 3 and 6 months, respectively.

Adult↗

Staff countertransference to borderline patients on an inpatient unit.

Borderline patients evoke unique countertransference responses among members of the treatment team: pejorative behavior, undue optimism, and pessimistic nihilism to these patients, along with difficulties in limit-setting, and fragmentation of the treatment team are common. Frequent meetings and open communication within the treatment team are recommended in order to minimize the splitting that is central to these countertransference constellations.

Acting Out↗

Acute experimental autologous fat embolism in dogs.

An experimental technique has been devised to study the acute respiratory and hemodynamic results of autologous fat embolism in dogs. By using a commercially available autotransfusion device, fat can be aspirated and reinfused into the venous circulation. Acute rises in pulmonary artery pressure and calculated pulmonary dead space can be produced, and arterial oxygen saturation is impaired. These changes correlate well with the appearance of intravascular embolized fat. Apparent intravascular clot formation is demonstrated, the fat droplet acting as a stimulus or nidus for clot formation. These changes were avoided when the infusate was first passed through a micropore filter.

Animals↗