PubMed Health⌕ Search

Biomedical subjects

D Sondag-Thull

Publications and source records attributed to D Sondag-Thull.

25 records · Page 2Linked to original sources
PubMed1986

[Production and characterization of monoclonal antibodies with P1 specificity].

Four monoclonal antibodies, with P1 specificity were obtained after fusion of myeloma cells and spleen cells from mice immunized with turtle dove ovomucoid. Immediately after the fusion, the culture supernatants were studied for specificity with panels of erythrocytes and red blood cells sharing rare phenotypes (P1K, P2K, p) in the P system. After cloning, four monoclonal antibodies were produced, these antibodies strongly agglutinate P1 red blood cells, specially when they are used with 3% of dextran or with a 350 mmol/l concentration of sodium.

Animals↗
PubMed1986

S-s-U-phenotype in a Caucasian family.

The S-s-U-blood group phenotype, commonly detected in Black populations, was found in a Caucasian family in which 4 homozygous U-negative members exhibit this phenotype. The erythrocyte blood group antigens and membrane glycoproteins from these donors have been serologically and electrophoretically characterized and compared to the U-negative red cells from Black people. Caucasian and Black S-s-U-red blood cells behaved identically since both lack Ss and U antigens and the minor red-cell membrane glycophorin B.

Black People↗
PubMedDate not supplied

Prevalence of hepatitis G virus in a haemodialysis unit.

BACKGROUND: Recently, a novel blood-borne virus has been identified and named hepatitis G virus. Transfusion is the main route of transmission. It is known that patients on maintenance dialysis are more susceptible to infections with parenterally-transmitted viruses than the general population. The aim of the present study was to determine the prevalence of hepatitis G infection in a Belgian dialysis unit. METHODS: The entire population of our dialysis unit (82 patients) was tested for the presence of hepatitis G virus (HGV) by reverse transcriptase polymerase chain reaction. History of transfusion or renal transplantation, coinfections with hepatitis B and C viruses, and serum aminotransferase levels were also tested. RESULTS: Thirteen patients (16%) were found positive for HGV-RNA. Among these patients, 69.2% were infected by the G virus alone, 15.4% were coinfected with B virus, and 15.4% with C virus. All but one patient had a history of transfusion. Ten of the thirteen infected patients (77%) had normal aminotransferase (< 30 UI/l). Three patients had elevated aminotransferase levels (23%); one was coinfected with B virus, one with C virus, and the last one had a diabetes-induced fatty liver infiltration. No liver biopsies were performed. CONCLUSIONS: It is concluded that infection with G virus is common among dialyzed patients. This high rate of infection could be related to previous transfusions, but may as well be due to nosocomial transmission. In our series, at least one patient has been contaminated by another road than transplantation or transfusion. Finally, it does not appear clearly that chronic infection with hepatitis G virus induces liver disease, as defined by elevated aminotransferase level.

Adolescent↗
PubMedDate not supplied

[HIV infection in women. Psychological and somatic obstacle].

We consider the word "impediment" in the meaning of what compels someone, makes someone feel uncomfortable. What are the consequences/implications of seropositivity for the woman in her sexual life, in her motherhood and how does she then cope with it? The following clinical observations account for the suffering induced by seropositivity and the diversity of the processes spontaneously set by HIV-infected women in their sexual life. To answer that suffering, the commonly used psychotherapeutical approach is a palliative one.

Adaptation, Psychological↗