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Biomedical subjects

D Strangfeld

Publications and source records attributed to D Strangfeld.

At least 55 records · Page 3Linked to original sources
PubMed1983

[Studies on central and peripheral hemodynamics using radiocardiography and Xenon-133 muscle clearance in patients with essential hypertension].

Examination of 80 patients with essential hypertension revealed a significant correlation between the tonus of peripheral muscular arterioles on the one hand, and the stage and duration of hypertension and age of the patients, on the other hand. The correlation between arteriolar tonus and indicators of cardiac pump function was less marked. The results confirmed the close relationship between changes of peripheral blood bed and development of hypertension. The use of 133Xe half-period for measuring the peripheral arteriolar tonus proved a simple, but informative method adding an important indicator of peripheral haemodynamics to the results of haemodynamic examination.

Adolescent↗
PubMed1983

[Unilateral catheterless determination of kidney function in hydronephrosis].

Whereas the value of quantitative separate determination of kidney functioning is undisputed for most urological and nephrological problems, its value for the judgement of hydronephrotic kidneys is doubted by various working groups. Using 15 mongrel dogs, the nuclide excretion at certain times, various calculation intervals and the results of separate functional analysis of hydronephrotic and non-hydronephrotic kidneys were compared. Due to the early nuclide excretion with an advanced secretion peak it is no longer acceptable to use a 2-minute calculation interval for hydronephrotic kidneys in dogs. If the upper limit of the calculation interval is prior to the secretion peak, there will be no overestimation of the hydronephrotic kidneys.

Animals↗
PubMed1982

[The behavior of blood pressure and peripheral hemodynamics in regular exercise therapy in patients with essential hypertension (stages I and II) of various age groups].

The authors report on the effect of a combined training programme decreasing blood pressure in male patients with essential hypertension (stage I and II) treated formerly not effectively with propranolol. Basis of the exercise treatment was the frequency of training which was established from the individual loading tests before the series of therapy. In three collectives of patients with hypertension of different age decreases of systolic as well as diastolic blood pressure could be ascertained statistically. With the help of the xenon-133 muscle clearance in most cases an improvement of the peripheral microcirculation could be proved. The mean functional vascular cross section (A) significantly increased under the training therapy.

Adult↗
PubMed1981

[Homologous umbilical vein and vena saphena transplants as possible means of vascular access in chronic hemodialysis].

For a patient in the chronic programme of haemodialysis an uncomplicated accession to the vessels is the prerequisite for an optimum medical and social rehabilitation. Each form of a subcutaneous arteriovenous fistula is to be preferred to an epicutaneous shunt prosthesis. The percutaneous puncture of large vessels is necessary for the rapid connection to the dialyses in acute situations. In long-term treatments often all autologous accessions to the vessels are used up. Homologous substitution material for vessels is increasingly used also in patients ongoing dialysis. Apart from the methods for gaining homologous material is reported on first experiences in the application of homologous grafts of the umbilical vein and of a homologous vena saphena graft in patients undergoing dialysis.

Humans↗
PubMed1981

[On the significance of combined kinesitherapy for the rehabilitation of ageing people with essential hypertension (author's transl)].

Proceeding from their investigations the authors have formulated the following questions: 1. How do ageing people with essential hypertension tolerate sauna treatment (hyperthermia)? 2. What is the optimum thermal load for effective antihypertensive treatment? 3. What is the optimum interval, i.e. how many sauna baths are recommended per week? 4. Does an anti-hypertensive combination therapy consisting of sauna baths and jogging produce the same or even better results in aged hypertensives than sauna treatment on its own?

Age Factors↗
PubMed1980

[The heart in hypertension].

After indications to the great epidemiologic importance of hypertensive heart disease and its relationship with the ischaemic heart disease several results are reported collected during the past 10 years by examinations of more than 500 patients for early diagnosis of cardiac insufficiency in hypertension. The methods of microcatheterization of the pulmonary artery and radiography have been used (even under ergometrical exercise) as well as the calibrated apex cardiography and the echocardiography. For the practising physician a classification of hypertensive heart disease with 4 phases or forms is proposed. The paper ends with a demonstration of the close relationship between prevention and treatment of hypertension as well as between hypertensive and ischaemic heart disease at the same time in a sense of the integrative role of heart insufficiency.

Cardiomegaly↗
PubMed1980

[Quantitative kidney function scintigraphy (FSG) on separate sides in urogenital tuberculosis].

Depending on degree and size of the changes the function of the tuberculous kidney is disturbed with different strength. With the help of the quantitative function scintigraphy by means of 131 J hippuran (sequence scintigraphy, ROI nephrography and side-separated clearance) 33 patients with urotuberculosis were examined and their course of the disease was observed. The greatest value has the function scintigraphy in progressed renal tuberculosis in the differential therapy (nephrectomy, organ-maintaining operation or conservative therapy) and control of the course.

Creatinine↗
PubMed1979

[Treatment of experimental immune complex nephritis with indomethacin].

Functional, histological and immune-histological examination were performed in altogether 64 Wistar-rats, in order to control the effect of a therapy with 2 mg/kg per body weight indomethazine lasting 2 months at the model of an experimental immune complex nephritis. In 44 rats after presensibilisation an immune complex nephritis was performed by intraperitoneal injections with human serum albumin which were repeated three times a week. 24 glomerulonephritis animals and other 20 animals without glomerulonephritis were daily administered indomethazin through a tube probe, the remaining 20 animals with glomerulonephritis served as untreated control groups. The excretion function of the kidney was tested before the beginning of the experiment, 2 weeks after the beginning of the therapy and the regular serum injections, respectively, and before the end of the experiment by determination of the biological half-life period of 131J-hippuran. In every case one day before this the proteinuria during 24 hours was determined. At the end of the experiment the kidneys were examined histologically and immune-histologically. The results showed that indomethazin does not lead to a clear influence on the proteinuria in the immune complex nephritis of the rat. The excretion of 131J-hippuran was significantly restricted, whereas the histological and immune-histological preparations in the animals with foreign serum injections showed clear changes of the glomeruli in the sense of an early stage of the immune complex nephritis, however, they did not show any essential influence by indomethazin. That is, indomethazin had altogether no favourable effect on the immune complex nephritis of the rat.

Animals↗
PubMed1979

[The effect of training on the physical fitness of patients with chronic kidney failure].

Apart from the specifically uraemically conditioned decreasing in vitality factors a physically inactivity which originates from the want of the patient or is iatrogenically induced, respectively is one of the causes for the decrease in physical vitality in patients with chronic renal insufficiency. 10 patients with chronic renal disease (serum creatinine 9.2 mg%) after an ergometric test were trained regularly twice a week for 30 minutes with a training intensity which corresponded to 80% of the load intensity. After a training duration of 15 weeks 9 of the 10 patients yielded a better result, in one female patient the bicycle-ergometric effect remained constant. The physical load capacity of the successfully trained 9 patients increased by 22.2 W from 80,5 W to 102.7 W. This corresponds to a 27.6% increase in vitality. After the end of the training the patients achieved a result which is higher than that of untrained patients with renal insufficiency in the same region of insufficiency. In comparison to healthy persons of the same age before the training the patients were to be loaded with 71% and after the training with 92% of the normal. The result of the training can also be read at a decrease of the heart rate and at a shortening of the recreation phase after constant load. The significant decrease of the systolic blood pressure on the 50 W-step indicates to a favourable influence of the RR-behaviour.

Adult↗
PubMed1979

[A-wave in calibrated apex cardiogram in hypertension. Studies during rest and after exertion].

Apexcardiographic examinations were carried out of 86 hypertensive patients without clinically manifest heart failure. The amplitude of the wave a (or the per cent fraction of the wave a of the total amplitude) and the maximal rate of wave rise, df/dta were statistically significantly higher in the hypertensive patients than in normal subjects. The findings are interpreted as a manifestation of an increased left ventricular rigidity and of an increased atrial contractility in hypertensive patients. No correlation was found between the apexcardiographic indicators checked and the indicators of the cardiac pump function. In 46 hypertensive patients, in addition, a dynamic exercise test was performed (50 W for 6 min); 1 minute after cessation of exercise an apexcardiogram was recorded. An increase in the a/T quotient (greater than or equal to 5%) was found in 20; a decrease (=5%), in 10; and no change (less than +/- 5%), in 16 hypertensive patients. The postexercise apexcardiographic changes had no correlations with haemodynamic changes occurring during exercise.

Adolescent↗