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Biomedical subjects

D Svejda

Publications and source records attributed to D Svejda.

3 recordsLinked to original sources

Computer supported decision making in therapy of arterial hypertension.

Therapy of hypertension is still more or less empirical. Several classes of antihypertensive medications are known, the effect of which is based on different mechanisms. The efficacy of the treatment is not always a reliable indication of the appropriate selection as a good therapeutical response can sometimes be achieved at the expense of humoral simulation. This can lead to harmful increased synthesis of trophic hormones. The program for PC called HYPERTENZE supports decision making in therapy of arterial hypertension. It gives a sequence of decisions based on clinical experience using a series of parameters. The program is using the Microsoft Access language of the Access database system and due to the Access Developers Toolkit it does not require Access to be installed on the user's computer. The program HYPERTENZE offers the user essential information and explanation of the decisions in a graded form. The price list of equivalent medications can be updated by the user himself. It seems that this program might be very useful for Czech general practitioners.

Antihypertensive Agents↗

Epidemiology tools program and selected medical applications.

In epidemiological research the calculation of appropriate measures of disease frequency is the basis for a comparison of populations and, therefore, the identification of disease determinants. Two frequencies being compared can be combined into a single summary parameter that estimates the association between an exposure and a disease. This can be accomplished by calculating either the ratio of the measures of disease frequency for two populations which indicates how much more likely one population is to develop a disease than another, or the difference between the frequencies which indicates how much greater the frequency of a disease is in one population compared with the other. In epidemiology we often need to compute measures of disease frequency mentioned above. We can do that by means of complex statistical software, but sometimes it is not easy or possible to use this software for an analysis of epidemiological data. At the EuroMISE Center of Charles University and Academy of Sciences in the framework of the research supported from grant COPERNICUS JRP-10053 the E. T. program (Epidemiology Tools) was developed. This program can be used for practical analysis of data from retrospective (case-control) studies or prospective (cohort) studies and for standardization. However, the program can be also a useful teaching tool in the epidemiology courses.

Adolescent↗

Evaluation of data in cardiology by new software tools.

We describe an analysis of cardiology data using new software tools. First we use data of 1417 men aged 40 to 50 years living in the center of Prague gathered in the twenty years lasting longitudinal study. We show some results of application of the programs E.T. (Epidemiology Tools) and CORE (COnstitution and REduction of data). Second we show the way of application of the program HYPERTENSION, that supports decision making in therapy of arterial hypertension.

Adult↗