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Biomedical subjects

D T Shaw

Publications and source records attributed to D T Shaw.

6 recordsLinked to original sources
PubMed1979

Multiple Y-V plasty.

Webs and contracture, whether congenital or the result of trauma or surgical excision, have been resurfaced with local tissue utilizing the principle of multiple Y-V advancement flaps. Initially the procedure was used in releasing broad scar contracture following a burn wound of the torso, and for congenital soft tissue shortening of the dorsum of the foot, both with gratifying results. The procedure was later used to obtain adjacent soft tissue for resurfacing defects of the nasal tip or ala, resulting from trauma and following the excision of a tumor. (For example, it enabled us to compensate for a rotation flap defect.) It is also useful for additional release of scar contractures of the digits and extremities after transposition of Z-plasty flaps, which can be further advanced using the Y-V advancement principle.

Cicatrix↗
PubMed1978

Theoretical modeling of fine-particle deposition in 3-dimensional bronchial bifurcations.

A theoretical model is developed for the prediction of the peak to average particle deposition flux in the human bronchial airways. The model involves the determination of the peak flux by a round-nose 2-dimensional bifurcation channel and the average deposition flux by a curved-tube model. The "hot-spot" effect for all generations in the human respiratory system is estimated. It is found that the peak deposition flux is higher than the average deposition flux by a factor ranging between 5 and 30, depending on the generation number. The importance of this peak to average deposition flux ratio on consideration of environmental safety studies is discussed.

Air Pollutants↗
PubMed1978

Adult onset nemaline myopathy.

A 47-year-old man had symptoms of nemaline myopathy for approximately 1 year. There were marked elevations of creatine kinase, a feature not previously described. Examination of the nervous system at autopsy failed to reveal any abnormalities.

Age Factors↗
PubMed1977

Acute supine respiratory failure due to bilateral diaphragmatic paralysis.

This report documents the first known case of bilateral diaphragmatic paralysis following blunt trauma to the chest. The important role of diaphragmatic function in maintaining ventilation, particularly with the patient in the supine position, is illustrated by the reduced total lung capacity, functional residual capacity, and vital capacity. Severe hypoxemia with the patient in the supine position, was markedly improved by elevation of the patient to 30 degree and was further improved by sitting the patient upright. Following an initial period of acute respiratory failure, the patient was managed acceptably by maintaining an elevated position for sleeping until diaphragmatic function returned, about nine months after the injury.

Accidents, Traffic↗
PubMed1976

Liver transplantation in a patient with cholangiocarcinoma and ulcerative colitis.

A 39 year-old patient with cholangiocarcinoma and pre-existing ulcerative colitis was successfully treated by orthotopic liver transplantation. He was given low doses of prednisone and azathioprine and survived for more than 9 months, dying with tumour metastases, thrombosis of the inferior vena cava and an intra-abdominal abscess. At autopsy the homograft showed little evidence of rejection. Preoperatively the patient had septicemia. Removal of his liver was difficult. The discrepancy between donor and recipient in size of blood vessels and the presence of two hepatic arteries in the donor caused problems during the vascular anastomoses. During the operation cardiac arrest occurred. Postoperatively there were several medical and surgical problems, including intraperitoneal and gastrointestinal hemorrhage, paralysis of the right dome of the diaphragm, sinus bradycardia, massive diuresis, peroneal nerve palsy, and one major and three minor episodes of rejection, which were reversed by giving pulse doses of methylprednisolone intravenously.

Adenoma, Bile Duct↗