Malaria placental infection with massive chronic intervillositis in a gravida 4 woman.
Explore the source record for details and available documents.
Adult↗
Biomedical subjects
D Tosi
Publications and source records attributed to D Tosi.
In vivo and ex vivo inhibitory effects of loratadine on histamine release in patients with allergic rhinitis.
BACKGROUND: The aim of this study was to evaluate the in vivo and ex vivo effects of the H1-antagonist loratadine on histamine release. METHODS: The study was designed as a double-blind, crossover trial. Ten patients with allergic rhinitis due to Dermatophagoides pteronyssinus were treated with loratadine (10 mg daily p.o.) and with placebo for 1 week, with a 2-week interval between the two treatments. Nasal lavages with saline solution were done before and after challenge with the relevant allergen at the end of treatments with loratadine and placebo. Venous blood was taken after treatments, and basophil histamine release induced by anti-IgE (10 microg/ml), N-formyl-methionyl-leucyl-phenylalanine (fMLP, 1 microM), and Ca2+ ionophore A23187 (1 microM) was evaluated by an automated fluorometric method. RESULTS: Treatment with loratadine attenuated early antigen-induced nasal obstruction, rhinorrhea, and itching. Nasal symptoms were accompanied by a significant histamine release in the nasal lavages collected 5 min after stimulation when the patients received placebo (median 4 ng/ml, range 1-28; P < 0.05). After treatment with loratadine, histamine release in the 5-min postchallenge lavages was almost abrogated (median 0.5 ng/ml, range 0-3; P < 0.01 vs placebo). Median anti-IgE-induced histamine release from basophils was 41.9% (range 27.8-79.2) after placebo and 30.0% (range 1.7-73.3, P < 0.05) after loratadine. Active treatment exerted an inhibitory effect also on basophil histamine release induced by fMLP and Ca2+ ionophore A23187. CONCLUSIONS: Treatment for 1 week with loratadine reduces allergen-induced nasal symptoms and inhibits in vivo and ex vivo histamine release in patients with allergic rhinitis.
Adult↗
Modifying migraine headache through rational stage directed hypnotherapy: a cognitive-experiential perspective.
Explore the source record for details and available documents.
Adult↗
[Erythrocyte volumetric distribution as simple and rapid test in screening for carriers of beta and alfa-thalassemic trait (author's transl)].
Explore the source record for details and available documents.
Erythrocyte Volume↗
[Gastric neoplasia in pregnancy: report of a case].
CASE REPORT: Gastric cancer in a 29 years old pregnant woman. A total of 109 cases were collected in the whole from 1916 to 1988; to these, we add one new case of a 29 years old pregnant woman observed in 1993 in Verona University Surgical Sciences Department. DISCUSSION: Cancer of the digestive tract during pregnancy is really rare and has poor prognosis. The diagnosis during pregnancy is difficult because the symptoms are frequently masked by factors related to the normal first trimester in pregnancy. X-ray are often restricted. Gastroendoscopy is applied to pregnant women only when evident symptoms are present such as: severe anemia, jaundice and weight loss. The incidence of inoperable cases is elevated such as the mortality in the operated cases. The whole survival rate after three years is 21%. CONCLUSION: Gastric cancer in pregnancy has a poor prognosis. The possible reasons are: delayed detection, low differentiation degree, restricted therapeutic approach because of pregnancy, personal factors as the patients' desire for a child, religious, ethical considerations.
Adult↗
[Endometriosis of umbilical cicatrix: a clinical case].
The Authors report a case of umbilical endometriosis in a 46-year-old patient. The woman came in for observation describing acute pain in the vicinity of the umbilical scar. The pain was occasional at first and then became steady and increased at the time of menstruation. Medical examination revealed a left paraumbilical nodule, measuring 1 cm in diameter. The patient underwent surgical treatment: the nodule was excised and the subsequent histological examination was diagnostic for umbilical endometriosis. The surgical excision was effective: at follow-up 3 months later, there was no recurrence and the patient was in good general condition.
Cicatrix↗
[Appendiceal mucocele associated with colonic neoplasm. Report of 2 cases and review of the literature].
Appendiceal mucocele is a rare entity frequently associated with colorectal cancer. We report two cases of mucocele associated with colorectal tumours. The first case (male, 64 yrs) is an appendiceal mucinous cystadenoma found incidentally during surgery for colon cancer. There is no evidence of disease after a 4-year follow-up. The second case (male, 66 yrs) is a mucocele associated with mucosal hyperplasia that was found during surgery for acute appendicitis with a periappendicular abscess. Endoscopic follow-up showed a rectal adenocarcinoma that was initially treated with local excision with T.E.M.. Examination of the pathology specimen documented vascular invasion and the patient underwent curative colorectal resection. The preoperative radiological and endoscopic diagnostic procedures and the current therapeutic approaches described in the literature are reviewed. The relevance of the association between appendiceal mucocele and colorectal cancer is emphasized. Thorough investigation of the colorectal tract is recommended after diagnosing an appendiceal mucocele.
Aged↗
[Splenic epidermoid cyst. Clinical case and review of the literature].
The occasional discovery of an epidermoid cyst of the spleen, rare kind of lesion, in a 25 years old man who underwent a US for urethral colic, permit to the authors a review of the literature. Treatment is individualized in a partial or total splenectomy.
Adult↗
[Anastomotic complications in the surgical treatment of rectal neoplasms].
The authors review the problems relating to the healing of colorectal anastomotic complications following anterior resection. They report on their own experience with 328 anastomoses, 281 of which constructed manually and 47 using a mechanical suturing gun. Following manual anastomosis, the reported incidence of clinical dehiscence was 1%, as against a 10.3% incidence of radiologically detectable dehiscence. In the cases of mechanically produced anastomoses the incidence of clinical dehiscence was 6.4%. In 2 cases stenosis developed as a result of the clinically manifest dehiscence following manual anastomosis. In the patients undergoing mechanical anastomosis, occlusion occurred in one case and stenosis in another, without any concomitant peri-anastomotic inflammatory processes; these complications were caused by a membrane extending between the margins of the anastomosis. The authors ascribe the greater incidence of clinically important dehiscence following mechanical anastomosis to a greater sensitivity of the mechanical suture to colonic contamination compared to the manual suture. According to the authors, the stenosis is attributable to inflammatory processes resulting from the dehiscence in the manual anastomosis cases and from the anastomotic structure in the mechanical-suture case.
Anastomosis, Surgical↗
[Spigelio's hernia. Anatomo-clinical considerations and description of 5 clinical cases].
Spigelian hernia, or ventro-lateral hernia is a rare clinical condition, it represents about 1.5% of hernial formation cases of the abdominal wall. It is localised laterally to the rectus muscle and emerges from the semilunar arch. The line, which joins the IX rib to the pubic tubercle, defines the limit between muscular and aponeurotic portion of trasversus abdominis muscle. Diagnosis often results misunderstood. As a matter of fact, this hernia has typically an intraparietal localization and the clinical picture seldom presents characteristic signs. The hernial sac and its content can be appreciated subcutaneously in only 2% of cases. It is estimated that about 50% of patients affected by this condition have a certain diagnosis before surgery. The early clinical signs are generally aspecific and deceitful, represented by oppressive grief and rarely by an abdominal wall tumor; it occurs that it starts with a complication: intestinal occlusion (23%), subocclusion (8%), strangulation (20%, but some authors report percentage up to 50%). We report 5 cases who came to our observation during the last 7 years; all patients underwent elective surgery, and specifically 3 patients in day surgery. Starting from the discussion of these cases, we review anatomy, etiology, clinical nature, instrumental investigation and surgical technique of this rare kind of hernia, comparing our experience to literature reported case histories.
Adult↗
[A rare case of colonic invagination due to leiomyosarcoma].
The authors report on a case of leiomyosarcoma with intussusception of the large bowel. They stress the importance of the clinical suspicion in targeting preoperative instrumental instrumental investigations.
Adult↗
[The clinical biomechanical interpretation of gunshot wounds. The general problems (IV). The propedeutic ABCs of the terminal ballistics].
If we want to enunciate the damaging potential of a bullet fired from a gun we have to express ourselves right from the outset in terms of destructive work, that is to say not only destruction of the structures the bullet passes through, but also, above all, destruction of the homeostatic condition. In modern terms, this is particularly true of the abdomen, which, in perspective, above and beyond any direct involvement, is a candidate for an interesting role. As regards the translation of this destructive force in mathematical language, formulae are proposed in kilogram-meters, feet per second and Joules. A basic factor in external ballistics, quite apart from the actual forces involved, is the trajectory in space, the hyperbola, though we should also reflect on the problem of resistance, which has such a considerable effect on the behaviour of the "ideal" bullet in the atmosphere (the smallest calibre for a given mass, with the attempt to rid itself of its forced subordination to the calibre of the barrel). This leads us on to the subsequent concept of the "ballistic coefficient" and, in itself definitively established the basic assumptions of terminal ballistics.
Abdominal Injuries↗
[Biomechanical-clinical interpretation of firearm wounds. General problems. X. Propedeutic ABC of terminal ballistics].
Any discussion of firearms which failed to take due account of the complex interaction between the weapon and its user would be missing the point. This interaction takes on a major role, particularly in the case of military ordinance weapons; their "optimal" use demands the maximum control of this interaction, which is of the utmost importance for the tactical role of the soldier-weapon system. The use of the latest long-barrelled ordinance firearms is more acceptable precisely because of their smaller calibre (which also means reduced interaction with the user). Today the traditional primacy of the long-barrelled weapon (now getting progressively shorter) is threatened by the short-barrelled gun cartridge, which we have seen used on an extensively scale in recent militia warfare. Paradoxically, it is precisely this cartridge, whose main shortcoming is its low propellant content (and thus reduced kinetic energy) which is expected to provide the kind of killing performance capable of snuffing out even "the dead man's last five seconds".
Biomechanical Phenomena↗
[Terminal ballistics. 1].
We have chosen to conceive of terminal ballistics as a violent and extremely rapid confrontation between two forms of resistance before the final state of rest is reached. This definition, which cannot help but don the admittedly loud and outlandish garb of physics, is the most promising for the purposes of biological interpretation. The main characters on this stage are two, but only one of these really plays the lead, namely the human target, which acts out the basic roles inherent in its physical make-up; the other, the bullet, remains a background figure, frozen in its walk-on part, and ready for the next performance. This modus operandi, which is no simplification, but rather an academic necessity, enables us to focus on images which stand out more clearly as a result of an intensive macroscopic spotlight which brings out the features of the individual phenomena, broken down into a succession of close-ups, and subtracts them from the cold physical nature of this or that form of inert matter, which here is merely an occasional, disagreeable witness, or even more, a standing from time to time for but one of the infinite facets of the biological composite being. Here, then, faced with a kind of exploded macrophotograph of a complex kaleidoscope, we see the animal universe, of which we capture so far the plasticity, the subdivisibility, the anisotropy and the cavitation.
Animals↗
[Terminal ballistics. 3].
This brief chapter, focusing essentially on a single topic, has been written in homage to Emile Theodor Kocker, a masterful exponent of the art of surgery and founder of the culture of terminal ballistics. For most of the literature we are indebted to Fackler and Dougherty, who, with the particular grasp, and fair of historians, act as guides on a trial which is only apparently retrograde, but which actually bears eloquent witness to the fact that even in the most physically tangible of arts, namely the art of surgery, inspired curiosity may help us to go well beyond the limits of our day and age. This chapter is also dedicated to the memory of another great surgeon, Vittorio Pettinari, who for one of the authors was an incomparable mentor and past-master of such curiosity.
Animals↗
[Cervical-mediastinal emphysema of abdominal origin].
Cervical mediastinic emphysema usually does not demand emergency procedures: nevertheless its ethiology must be promptly assessed though his achievement may prove less than easy owing the vague clinical presentation and to the limits imposed by regional topography. Among the possible etiologic factors one should take into account the rare abdominal source too. Indeed the cervical region is connected to the retroperitoneal space through a virtual "visceral space" via the thoracic cavity and some diaphragmatic break-throughs variable in size. The communication allows, in some pathologic conditions, the unopposed circulation of air and fluids. Our interest in the topic is due to the occurrence of a cervical mediastinic emphysema in a patient suffering from a colonic perforation.
Adult↗
[Cystic lymphangioma of the transverse mesocolon simulating neoplasm of the pancreatic tail].
Mesenteric cysts are uncommon lesions interesting surgeons above all for frequently difficulties in the preoperatory diagnosis. The role of radiology is to demonstrate the nature of these abdominal masses, but only with surgery we can establish a definitive histologic diagnosis. The authors report a case of a lynphangioma of the transverso mesocolon, miming a pancreatic neoplasm.
Adult↗
[Perforated diverticulum of the cecum: a difficult preoperative diagnosis].
A patient was admitted for a suspected appendicitis; occasionally, a roentgenogram of abdomen, an echography and a tomography: confirmed the suspect. At laparotomy a perforated diverticulum of cecum is suddenly reported: a segmentary resection of ascending colon is performed. Authors remark, according to literature, that preoperative diagnosis of perforated cecal diverticulum is difficult even today, in spite of diagnostic procedures.
Cecal Diseases↗