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Biomedical subjects

D Tyndall

Publications and source records attributed to D Tyndall.

10 recordsLinked to original sources

Comparison between PAI and quantitative digital radiographic assessment of apical healing after endodontic treatment.

OBJECTIVE: The purpose of this study was to compare both subjective (Periapical Index, PAI) and objective (densitometric) radiographic evaluation of healing after endodontic treatment for apical periodontitis. STUDY DESIGN: Standardized radiographs of 103 teeth taken at baseline (immediately after endodontic treatment) and at 1, 4, 12, 26, and 52 weeks were evaluated. Consensus PAI scores obtained from 7 calibrated observers served as "true scores." Densitometric estimates of periapical status were obtained from digitized radiographs as the ratio of mean gray value of an area of radiolucency (AR) to an adjacent and similar-sized normal (N) area (AR/N). The selected regions of interest on baseline images were automatically superimposed on postoperative images. All estimates of change were measured with respect to baseline. The subtraction estimate was expressed as AR(S)-N(S). Linear regression was used to analyze longitudinal changes against baseline and to assess the relationship of PAI and AR/N and of change in PAI with respect to baseline and AR(S)-N(S). RESULTS: Five hundred fifty-six PAI scores were generated, with 547 AR/N values and 444 subtraction estimates. PAI, AR/N, and AR(S)-N(S) demonstrated statistical significance for change (P < or = .05) starting at 12 weeks. PAI was significantly correlated with AR/N (P < .0001), as was CHPAI with AR(S)-N(S) (P < .024). CONCLUSION: The PAI and 2 densitometric estimates (AR/N and AR(S)-N(S)) detected healing of apical periodontitis at 12 weeks after treatment. No difference could be observed among the methods.

Absorptiometry, Photon↗

Diagnosis of external root resorption using TACT (tuned-aperture computed tomography).

This study compared the ability of the TACT system of imaging and conventional D-speed film to detect simulated resorptive defects in cadaver teeth and jaws. Mandibular human jaw blocks were prepared and then split through the teeth in a mesial to distal direction so that the mandibular halves could be opened and reassembled when necessary. One half of each of 42 teeth was extracted, and areas on the tooth and corresponding bone identified to be studied. The jaws were opened and reassembled after no defects or after defects of different sizes (0.25, 0.5, 1.0, 2.0 mm) were placed in the tooth and the corresponding bone at predetermined evaluation areas. The teeth were imaged after each stage with conventional D-speed film using a standard paralleling technique, and with a modified orthopantomograph OP100 machine using a Schick #2 size CCD sensor as the image receptor. The source images were registered and TACT slices were generated using TACT Workbench Software. Three observers were asked to identify the presence of resorptive defects in the conventional film group and the TACT image group using specific criteria. TACT imaging was statistically superior to conventional radiographs in detecting defects that were present (Wilcoxon matched pairs signed ranks test P = 0.003). This was true for all sizes of defects examined. There was no difference between the two modalities when a defect was not present.

Cadaver↗

Identification of root canals in molars by tuned-aperture computed tomography.

AIM: To compare the tuned-aperture computed tomography system of imaging to conventional D-speed film for their ability to identify root canals in extracted human molars. METHODOLOGY: Thirteen maxillary and six mandibular human molars were mounted in acrylic blocks to simulate clinical conditions by surrounding the teeth with a radiodense structure. The teeth were then imaged with conventional D-speed film using a standard paralleling technique, and with a modified orthopantomograph OP100 machine using a Schick no. 2 size CCD sensor as the image receptor. The source images were registered and TACT slices were generated using TACT Workbench Software. Three observers were asked to identify the number of canals in the conventional film group and the TACT image group using specific criteria. Ground truth was established by cross-sectioning the teeth at the coronal, middle, and apical thirds of the roots and directly visualizing the root canal morphology. RESULTS: TACT imaging detected 36% of 4th canals in maxillary molars and 80% of third canals in mandibular molars. Conventional film detected 0% of fourth canals in maxillary molars and 0% of third canals in mandibular molars. The differences in canal detection between the two techniques were statistically significant (Wilcoxon matched pair sign rank test, P = 0.001). CONCLUSIONS: In this study, the TACT system of digital imaging was superior to conventional film in the detection of root canals in human molars and may be useful for the detection of root canals that will probably be missed upon conventional X-ray examination.

Dental Pulp Cavity↗

Clinical and in vitro film quality comparison of manual and automatic exposure control in panoramic radiography.

OBJECTIVE: Automatic exposure control has been used successfully in medicine to improve image quality and reduce the number of retakes necessitated by inadequate operator selection of exposure factors. The purpose of this study was to assess the influence of automatic exposure control on panoramic image quality. STUDY DESIGN: A total of 352 patients were imaged with either the OP 100 or the Orthophos Plus panoramic machine. An expert consensus panel judged film quality using a 5-point scale. Differences in quality that would have resulted from the use of operator-determined exposures were calculated through use of an algorithm validated with test images of a human phantom. RESULTS: McNemar's test demonstrated significant improvements in quality with automatic exposure control (P = .001) in comparison with manual exposure control. No quality difference was found between the 2 machines (P = .9661). Manual exposure selection by oral and maxillofacial radiology residents was better than selection by technologists and assistants (P = .006). CONCLUSIONS: This study confirms the utility of automatic exposure control for panoramic radiography.

Adult↗

Quantitative radiographic follow-up of apical surgery: a radiometric and histologic correlation.

The objective of this study was to establish an objective method for evaluating the treatment outcome of apical periodontitis (AP). AP was induced in the mandibular premolars of beagle dogs and apicoectomies were performed with retrofilling. Standardized periapical radiographs were taken immediately after completion of treatment and at 6 months. Ten pairs of standardized radiographs of 33 treated roots were analyzed. Radiographs were digitized and subtracted after warping and gamma correction. Areas of AP and adjacent normal areas (N) in digitized original and subtraction images were analyzed using eight radiometric computations. These computations were compared with subjective histologic evaluation and objective quantitative histomorphometry of the periapical condition at 6 months. The average gray value for AP on the subtraction images was found to have significant correlation with both objective (multiple regression p < 0.01) and subjective histology (logistic regression p < 0.01). Digital subtraction may be a useful tool in endodontic apical surgery assessment.

Absorptiometry, Photon↗

A quantitative analysis of dental radiography quality assurance practices among North Carolina dentists.

OBJECTIVE: The purpose of this study was to assess the level of compliance with dental radiography quality assurance recommendations on the part of dental practitioners in the state of North Carolina and to determine whether the age of the practice was an influential factor affecting compliance. STUDY DESIGN: On-site survey inspections by state officials using measurement devices and questionnaires were used to assess x-ray machine parameters and gather information about quality assurance practices in private offices in the state of North Carolina. RESULTS: There were approximately three intraoral units per facility, with an average entrance skin exposure of 267 mR per bitewing radiograph. There were no significant differences associated with the age of the practice in quality assurance practices except with respect to the type of processor used: dentists who had been in practice for more than 20 years used manual processing more frequently than those who had been in practice for less than 20 years (p = 0.001). CONCLUSIONS: Most practices showed a high level of compliance with equipment function requirements. North Carolina dentists are making an effort to comply with the American Academy of Oral and Maxillofacial Radiology recommendations. However, the use of faster film and rectangular collimation was much less than expected. Only 9% of the participants reported using E-speed film exclusively, and only 7.33% reported using rectangular collimation.

Dentists↗

Effect of projective aspects variations on estimates of changes in bone mass using digital subtraction radiography.

This study tests the hypothesis that estimates of changes in bone mass derived from subtraction data obtained in accord with published methods are independent of the spatial aspect of the lesion being evaluated when calibrations are performed independently. Nineteen sliver-shaped bone chips ranging in mass from approximately 1 to 35 mg were orientated with broad side parallel to the facial surface of a hemisectioned dry human mandible and radiographed using conventional exposure parameters on conventional E-speed dental X-ray film. Also attached to the film was a standardized aluminium calibration wedge that facilitated quantitative analysis of resulting subtraction data using established methodology. The effects of scatter were simulated by the addition of a 1-cm-thick slab of tissue-equivalent plastic. A second series of exposures then was produced using the same respective spatial chip locations and projection geometries but each chip was reorientated such that its broad side was now positioned perpendicular to the mandibular facial surface. Finally, a comparable series of control exposures was produced without any chips or calibration wedge to facilitate subtraction. When paired bone estimates derived from the two chip orientations were compared (paired comparisons) using Student's t-test, a statistically significant difference (p < 0.05) was observed. These results also were tested for statistical significance using the non-parametric Wilcoxon test. As with the parametric analysis, the discrepancy between the parallel and perpendicular mass estimates was found to statistically significant (p < 0.05). The methods employed in this investigation thus resulted in bone mass estimates that varied significantly depending upon lesion orientation.

Absorptiometry, Photon↗

Treatment of experimental osteomyelitis with antibiotic-impregnated bone graft substitute.

The model of Norden was used to induce osteomyelitis in the left tibia of New Zealand White rabbits. Twenty-one days following inoculation, the animals had primary debridement and then were randomized into one of three treatment groups. Group I received no additional treatment; in Group II, plain hydroxyapatite beads were packed into the defect; and in Group III, gentamicin crobefat-loaded hydroxyapatite beads were packed into the defect. The animals were observed for 40 days after the primary debridement and then were killed. The intensity of infection was determined by swab cultures and quantitative bacterial cultures of the debrided material. At primary debridement, all of the animals in each group were equally infected. At the time of secondary debridement, only the animals in Group III had a statistically significant reduction in infection (p < 0.001). In this study, we demonstrated that an antibiotic-loaded osteoinductive ceramic bead can effectively eliminate bacteria from an osteomyelitic cavity.

Animals↗

Accuracy of quantification of mandibular condyle displacement in digitally subtracted linear tomograms.

Using a TMJ skeletal phantom, we assessed validity and reliability of digitally subtracted linear tomographic images to quantify condylar position changes. Horizontally corrected frontal and lateral tomographic images were made with the condyle in a 'centred' position and displaced by 1, 2 and 3 mm increments in two of three directions (inferior, and posterior, or lateral). Film images were sequentially subtracted and then randomized so that observers were blinded to the amount and direction of condylar movement. Averages of three measurements of the dark bands representing condylar shifts were made using a digitizing tablet. The study utilized a nested design where the series of film images was subtracted twice and each subtraction was read twice by two examiners. We repeated the study with a second series of films treated in an identical manner. Average differences from expected values were similar for frontal and lateral techniques and all directions and increments of displacement. Typical average difference for any increment was less than 0.1 mm. Standard deviations in measures were similar across techniques and increments and were typically less than 0.1 mm. Significant variation in the absolute value of differences between measured and expected values by direction of condylar displacement was attributed to greater accuracy of registration on the vertical axis for frontal images. A significant source of variation in the study design element 'film set' was attributed to errors in repositioning the phantom.(ABSTRACT TRUNCATED AT 250 WORDS)

Analysis of Variance↗

Digitally subtracted linear tomograms: three techniques for measuring condylar displacement.

Using digital subtraction enhancement, we compared the accuracy of three tomographic technique variations for quantifying small changes of condylar position. A phantom made of skeletal material and an adjustable mechanical stage provided 0.1 mm positioning accuracy of the condylar segment. Linear tomographic images were made with the condyle in a centered position and at each of three 1 mm increments of displacement in two of three directions (inferior, and posterior or lateral). Variations for frontal views included arbitrary (+20 degrees) and individualized (+10 degrees) horizontal correction of the condylar axis. Variations for lateral views included the arbitrary and individualized correction and a fully corrected vertical (+5 degrees) and horizontal (+10 degrees) adjustment. Blinded observers made repeated measurements on randomized subtraction images with a digitizing tablet. Film images were subtracted twice, and each subtraction was read twice by two examiners. The study was repeated with a second series of films treated in an identical manner. Mean values for measurements, standard deviations, and absolute values of differences between measured and expected values were calculated for each subtraction. Analysis of variance identified statistically significant sources of variation in repositioning the phantom and producing exact displacements of the condyle. Average absolute value of differences from expected values were similar for the three techniques and for frontal and lateral orientations and increments of displacement. Typical absolute value of difference for any technique was 0.2 mm for posterior, 0.2 mm for lateral, and 0.1 mm for inferior displacements. Significantly greater accuracy of inferior displacement measures was attributed to greater accuracy of registration of the fossa in its cranio-caudal dimension.(ABSTRACT TRUNCATED AT 250 WORDS)

Analysis of Variance↗