Biomedical subjects

D V Bomhard

Publications and source records attributed to D V Bomhard.

3 recordsLinked to original sources

PubMed1977

On the histogenesis of osseous structures in epithelial tumours. A light and electronmicroscopical study illustrated at the so-called mixed tumour of the mammary gland in bitches (author's transl).

The osseous areas of 126 canine mixed tumours of the mammary gland were studied by light microscopy. Seven cases were investigated in detail using the electronmicroscop. It is suggested, that these structures develop by enchondral ossification. There ist no indication that myoepithelial tumour cells play a role in formation of osteoid or osseous foci. The cells taking part in enchondral ossification in such tumours cannot be distinguished from cell normally found in enchondral ossification. They derive from the stroma growing into the chondroid matrix. Areas developed by enchondral ossification therefore cannot be considered as tumour tissue in the true sense.

Animals↗

PubMed1975

[Electronmicroscopic studies on solid mammary carcinomas in bitches].

The electronmicroscopic findings of nine solid mammary carcinomas in bitches are described as well as the observations on tumour cells within lymphatic vessels. In the primary tumours basement membranes surround the cords of tumour cell. In five cases, particularly in two, there are cells with long intracytoplasmic filaments measuring about 65 A thick. The filaments are arranged along the axis of the cells and show focal densities. These cells are presumed to be myoepithelial tumour cells. In eight of the nine tumours there are also carcinoma cells with short single or bundled intracytoplasmic filaments of approximately the same thickness (65 A). These however show no specific order, they are perinuclear or lie in between the organelles. They are called tonofibrillae. Viruses or virus-like particles have not been found.

Animals↗

PubMed1975

[Oncocytes in a mixed canine mammary gland tumour].

The electronmicroscopic findings of a canine mixed mammary gland tumour containing oncocytes, are described. The tumour consists of small myxoid foci and glandular formations with an organoid structure. The glandular walls are composed of myoepithelial differentiated cells and epithelial cells. Most of the latter are oncocytes and characterized by an extensive amount of pathic mitochondria. The myxoid foci consist of myoepithelial differentiated cells.

Animals↗