PubMed HealthSearch

Biomedical subjects

D V DiGiulio

Publications and source records attributed to D V DiGiulio.

2 recordsLinked to original sources

Symptoms following mild head injury: expectation as aetiology.

An affective, somatic, and memory check-list of symptoms was administered to subjects who had no personal experience or knowledge of head injury. Subjects indicated their current experiences of symptoms, then imagined having sustained a mild head injury in a motor vehicle accident, and endorsed symptoms they expected to experience six months after the injury. The checklist of symptoms was also administered to a group of patients with head injuries for comparison. Imaginary concussion reliably showed expectations in controls of a coherent cluster of symptoms virtually identical to the postconcussion syndrome reported by patients with head trauma. Patients consistently underestimated the premorbid prevalence of these symptoms compared with the base rate in controls. Symptom expectations appear to share as much variance with postconcussion syndrome as head injury itself. An aetiological role is suggested.

Activities of Daily Living

Changes in cerebral functioning associated with normal aging.

It has been suggested that the normal aging process is characterized by a pattern of neuropsychological performance decline that implies relatively greater vulnerability of right-hemisphere functions. This hypothesis was tested in a sample of 68 volunteers aged 20-75 who were free of systemic and neurologic illness. Neuropsychologic measures of lateralized and focal function were specifically selected to eliminate systematic procedural differences among tests (e.g., timed vs. untimed, overlearned vs. unfamiliar). Inferences about the localizing significance of each measure were based on previously demonstrated double dissociation of function in lesion studies. Results suggested that declines in cerebral efficiency are not differentially lateralized. Age correlated performance changes implied bilateral reduction that was significantly more pronounced on operations associated with frontal-lobe function. Anatomic and theoretical explanations for this pattern were discussed.

Adult