Vitreous effects on scar tissue formation.
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Biomedical subjects
Publications and source records attributed to D V Greer.
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The visual prognosis of patients suffering from retinal branch vein occlusion complicated by macular oedema is assessed in relation to the degress of capillary fallout. Extensive retinal capillary fallout associated with macular oedema was found to confer a poor visual prognosis in a series of 89 patients followed for an average time of 14 months. If the degree of capillary fallout associated with marular oedema was minimal, the visual prognosis was considerably improved.
A system has been developed which enables continuous monitoring and recording of circulating fluorescein in the retinal blood vessels. This is achieved with minimal modification of a Zeiss fundus camera. A night vision television camera (lkegami) is used with illumination provided by the standard observation light of the fundus camera. This method offers advantages over standard fluorescein angiography in patient comfort, information obtained and the immediate evaluation of the fluorescein angiograms being available.
Contrast sensitivity functions to vertical sinusoidal gratings have been measured in 135 subjects ranging from 3 to 29 years of age. The reported contrast sensitivities for all spatial frequencies increased steadily with age, reaching adult levels during adolescence. The usefulness of these functions as a clinical test is discussed.
A systematic ophthalmological, medical, and biochemical screening of a rural population of diabetics in Western Australia is being carried out. A team of ophthalmologists, physicians, and paramedical personnel establish regional screening centres on a voluntary basis at weekends. Every attempt is made to locate and examine all known diabetics. All patients are given a thorough ophthalmic examination including standard multiple field colour fundus photography. Thorough physical examination includes assessment of cardiovascular and neurological status. Biochemical parameters include random blood sugar, urine analysis, serum creatinine, glycosylated haemoglobin, cholesterol, and high density lipoprotein. A detailed questionnaire and interview is carried out to assess the historical degree of control and the patient's knowledge of the control and management of diabetes. The sample now comprises an unselected population of 400 diabetics living in rural areas and allows comparison of areas which have scarce medical services with centres that are well supplied with medical practitioners. Incidence of retinopathy varies from 25 to 36 per cent of the diabetic population. Positive correlations of retinopathy have been found with duration, age, hypertension, level of control assessed biochemically at the time of examination, presence of ischaemic heart disease, peripheral neuropathy, and renal disease. Smoking also correlates positively. The data provide a baseline by which attempts to alter diabetic knowledge, management, and control may be measured in follow-up studies.