Elevated pulmonary artery pressure as a predictor of mortality.
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Biomedical subjects
Publications and source records attributed to D V Pecora.
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Postpneumonectomy pulmonary distention has been considered harmful by many clinicians. We measured changes in pulmonary compliance and vascular resistance with distention in five dogs. There was no significant change in compliance and vascular resistance in the range of pulmonary distention seen following pneumonectomy.
Gastric mucosa was removed from five dogs and allowed to regenerate. Serial scintiscans after administration of 99mTc pertechnetate revealed gradual increase in gastric radioactivity, so that by 4 weeks it appeared as intense as preoperatively. By this means it was possible to follow the progress of gastric mucosal regeneration. The authors suggest that serial 99mTc scintiscanning might prove useful in evaluating the hypothesis that Barrett esophagus is due to replacement of esophageal squamous epithelium by gastric columnar epithelium.
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During lung transplantation experiments, the lower respiratory tracts of dogs were examined by bacteriologic cultural technique pre- and postoperatively. Three methods were used to obtain culture material: transtracheal aspiration, lung puncture, and lung biopsy collection. Both before and after operation, infections were commonplace. Antibiotics given at the time of operation tended to suppress infection.
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