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Biomedical subjects

D Vukić

Publications and source records attributed to D Vukić.

5 recordsLinked to original sources

[Osteopoikilosis--case report].

A very rare case of osteopoikilosis, a disease which is an asymptomatic, genotypical osteopathy with an unknown cause, is described. Most often it is discovered by accidental radiography and it is characterized by the appearance of spotted and oval foci of compact cortical and lameral bone inside the canselous bones. The most common localization of these disorders are epiphyses and metaphyses of the long bones. The disorders have a static character and they do not demand any kind of treatment.

Adult↗

[Early functional and anatomic results after total condylar knee prosthesis implantation].

The results of total knee replacement in 30 patients have been analyzed. Total knees were implanted during 1990, and the shortest follow-up time after the operations amounted to 6 months. All 30 total condylar prosthesis were of Insall-Burstein posterior stabilized design. The average age of the operated patients was 61 years. Osteoarthritis caused serious knee damage in 21 patients and was the indication for the operation; in 7 patients it was rheumatoid arthritis; in 1 patient synovitis villonodularis; and severe posttraumatic osteoarthrosis in 1 patient. In 18 patients axial knee deformity was noted prior to operation in the sense of valgus or varus. The continuous passive motion machine was used in the postoperative treatment of all patients. Clinically acceptable results were obtained in 90%. Wound healing complications were noted in 2 patients. Full axial deformity correction was achieved in all the patients with a full extension and flexion of over 90 degrees in the operated knees. Preliminary results after the implantation of this type of prosthesis are very encouraging and justify it's further routine use.

Adult↗

[Incorporation of nonvascularized auto- and allotransplanted bone into the site of bone defects].

It is generally accepted viewpoint that free bone grafts do not survive transplantation, that the incorporation of the autograft is faster and safer than the one of the allograft, and that the immunological processes disturb the process of revascularisation and reossification of the graft, although they stimulate the process of absorbtion. The process of graft incorporation into the host's bone was followed up in 8 dogs, i.e. 16 knees. In 10 knees the medial tibial condyle was replaced by autogenic implants made of patella, thickness of 6-8 mm. and fixed by Kirschner wire. The process of allograft incorporation was studied in 6 knees, where the medial tibial condyle was replaced by the donor's graft. The process of the graft incorporation was followed-up by x-ray studies and after sacrificing the animals during the interval starting from 2 months to a year since the operation had been performed, while in the allograft group the follow-up was during the interval starting from 1 up to 5 months. The obtained results point out that the incorporation of the bone grafts thinner that 1 cm happens within first 8-10 months after the operation. The process of incorporation during this period happens at almost the same speed in both groups. If there are no technical errors while implanting, practically all the grafts of this thickness will be incorporated into the host's bone, i.e. completely reosified and revascularized. The congruity of the joint and the rigidity of the fixation play the main role in the fate of the graft within the first months after the operation.

Animals↗

[Degenerative arthritis of the knee joint after allotransplantation of the joint surface without immunosuppression].

Degenerative arthritis of the knee joint after resurfacing of the knee with fresh osteochondral allograft occurs frequently and was noticed a long time ago. The main causes can be: incongruity of the joint, when the allograft slips so that its surface is out of normal line, inadequate internal fixation different methods of cartilage preservation which are lethal to cartilage, broken grafts as well as immunological reaction to the graft. The experiment was conducted on 5 dogs, i.e. 10 knees. As for operated knees, the medial tibial condyle was replaced by fresh osteochondral allograft taken from the other animal, without preservation, performing precise operative technique and rigid internal fixation. These allografts were followed-up by x-raying them and after sacrifying the animals. The following-up of the development of the degenerative process continued up to 6 months after transplantation. The obtained results point out all the attitudes concerning all the other arthroplastic procedures (such as the precise reconstruction of the joint surface and the rigid internal fixation) should be respected. In spite of this, degenerative arthritis still exists in some cases as the result of immunological reaction to the graft, the process which may start within 6 months after transplantation.

Animals↗