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Biomedical subjects

D W Bethune

Publications and source records attributed to D W Bethune.

15 recordsLinked to original sources

Use of partial cardiopulmonary bypass during the anhepatic phase of orthotopic liver grafting.

Femoro-femoral partial cardiopulmonary bypass has been used in two patients under going orthotopic liver allografting who had severe cardiovascular disturbances on trial clamping of their venae cavae. Flows of 2-3 litres/min resulted in satisfactory cardiovascular control during the anhepatic phase in each ase. A third patient who tolerated caval clamping withstood the grafting without bypass. Having bypass available for use in critical cases could increase the safety of orthotopic liver transplantation.

Adult

Day case anaesthesia and memory.

Two simple anaesthetic techniques were administered to forty healthy women undergoing minor gynaecological surgery. There was a significantly shorter immediate recovery period following the use of a fentanyl and methohexitone technique. Memory function testing revealed an impairment of the ability to retain new information following anaesthesia. This returned to normal within 3 hr.

Adult

A comparative study of condenser humidifiers.

Three currently available condenser humidifiers were studied to assess their ability to conserve water loss and to measure the resistance imposed by the apparatus. The value and possible effectiveness of these devices in clinical practice is discussed.

Anesthesia, Endotracheal

A safety block for scavenging systems.

A safety block is described which protects the patient from expiratory obstruction when using scavenging systems, and provides the anaesthetist with a visual and auditory check on the functioning of the system.

Anesthesia, Inhalation

A simple cooling circuit for topical cardiac hypothermia.

Rapid uniform cooling of the heart is the most important requirement of any method using local hypothermia for protection of the myocardium during open intracardiac surgery. We report the construction and operation of a recirculation cooling circuit comprising a reservoir, pump, and heat-exchanger for this purpose. It is operated by the perfusionist and can deliver up to 1 litre of fluid per minute at 4 degrees C into the pericardium or interior of the heart. Advantages of the system include rapid cooling of the myocardium, simplicity of operation, and applicability to all routine cardiac surgical procedures.

Aortic Valve

Performance of heat exchangers used in whole body perfusion circuits.

The performance of some commonly used heat exchangers has been investigated with particular reference to the effect of varying the water flow. The results demonstrate that there is considerable variation in the performance of most units when the water flow is changed. It is suggested that more information should be provided by the manufacturers of heat exchangers and that there should be a supply of water in cardiothoracic theatres at a sufficient pressure to allow the full performance of the heat exchangers to be realized.

Blood Flow Velocity