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Biomedical subjects

D W ESPLIN

Publications and source records attributed to D W ESPLIN.

At least 19 recordsLinked to original sources

Spinal reflexes and seizure patterns in the two-toed sloth.

In striking contrast to the seizure patterns of other animals, the electroshock seizure of the sloth consists of weak extension followed by tonic flexion and terminal clonus. A similar pattern is seen with direct spinal cord stimulation. Strychnine produces a pure flexor convulsion. In the spinal sloth, painful stimulation of one foot causes extension at some joints of that limb and strong flexion at all joints of the contralateral limb.

Animals↗

Impairment of muscle stretch reflexes in tick paralysis.

Experiments with tick-paralyzed dogs and woodchucks have shown impairment of stretch reflexes in addition to partial paralysis at the neuromuscular junction. Stretch reflexes disappear very early during paralysis, whereas nociceptive reflexes do not appear to be directly affected. The early incoordination and the ascending nature of the paralysis may be related to impairment of stretch reflex pathways.

Animals↗