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Biomedical subjects

D W Lamb

Publications and source records attributed to D W Lamb.

At least 19 recordsLinked to original sources
PubMed1991

The treatment of longitudinal radial deficiency.

Absence of the radius is the commonest of the longitudinal deficiencies but is itself quite an unusual congenital anomaly. No one surgeon is likely to encounter the condition more than once or twice in a career and there is a strong case for congenital upper limb conditions to be collected into special clinics. The pathology and methods of surgical treatment are reviewed. It is a difficult condition to treat but there is no doubt that function and appearance can be improved (Pulvertaft, 1973). Pollicisation of the index finger should be considered and can often greatly improve the function.

Hand Deformities, Congenital↗
PubMed1988

A new prosthesis for the upper limb.

We describe the development of a body-powered upper limb prosthesis fitted with a cosmetic functioning hand. The features and advantages of the new design--the PMR (Princess Margaret Rose) prosthesis--are discussed and the clinical results in 15 patients fitted with the prosthesis after above-elbow amputation are described.

Adult↗
PubMed1985

Ulnar instability of the metacarpophalangeal joint of thumb.

A method of reconstruction of the long standing rupture of ulnar collateral ligament of the thumb is described. Its advantage is the tightness with which the tendon used for repair can be sutured to achieve maximum stability. This has been used in eight patients in the past four years and provided a stable and painless thumb.

Finger Injuries↗
PubMed1984

"Rugby finger"--avulsion of profundus of ring finger.

The results of tendon grafting following avulsion of the profundus tendon to the ring finger ("Rugby finger") are described. Function in the hand was improved in all cases and this is a method of treatment which should be considered by the surgeon experienced in tendon grafting in those patients who are young and well motivated. The exact reason for the common involvement of the ring finger is not clear but the unique lumbrical origin from that profundus may be an important factor tethering the tendon in the palm, and this is suggested as the possible cause of this injury.

Adolescent↗
PubMed1984

Some thoughts on the current state of treatment of the upper limb in traumatic tetraplegia.

Traumatic tetraplegia often affects healthy young men. The medullary lesion is located at C6 in 75% of cases. The author on the basis of 20 years of experience believes it possible to improve independence and life quality by surgical procedures such as tendon transfers, which are the most often used, for restoring two important functions: active elbow extension and active hand grip. The restoration of elbow extension is accomplished by Moberg's procedure of transferring the posterior tendon of the deltoid onto the triceps. The results are very satisfactory. To restore hand grip the author makes use of the first radial tendon transferred onto the deep common flexor, and for the thumb, the long supinator onte the long flexor of the thumb. Definite functional improvement was found in 33 of 45 cases.

Arm↗
PubMed1984

Dislocations of the lunate with and without fracture of the scaphoid.

A review of 61 patients with dislocation of the lunate (some with and some without fracture of the scaphoid) showed that the majority had satisfactory results at an average follow-up of three and a half years. Most patients with a simple dislocation had a good or satisfactory result; radiological instability was noted in a quarter of the wrists but was not often associated with symptoms. Two-thirds of the patients with an associated fracture of the scaphoid had a good or satisfactory result. Immediate percutaneous wire fixation of the reduced scaphoid, whether it is fractured or not, is the best way of maintaining normal anatomical relationship while the ligaments and fracture heal; this may further improve the prognosis. In most cases extreme dorsiflexion of the wrist appeared to be the mechanism of injury.

Adolescent↗
PubMed1984

A wrist-powered hand prosthesis.

This paper describes a prosthesis for patients who have had a partial amputation of the hand, or who have congenital absence of all or part of the hand. The prosthesis incorporates a new concept whereby the grip is operated by flexion and extension of the wrist. A covering for the prosthesis has been developed using a silicone polymer which produces a lifelike flexible glove. Thirteen patients have so far been fitted with this type of prosthesis, which can give good function and cosmesis.

Amputation, Traumatic↗
PubMed1984

A study of liver microsomal enzymes in rats following propoxur (Baygon) administration.

Groups of rats were given either propoxur, were left as untreated controls, or were given phenobarbital, DDT, chlordane or toxaphene which are known to induce liver microsomal detoxification enzymes. Microsomal enzyme activity was measured by testing the ability of liver homogenates to degrade EPN (O-ethyl O-(4-nitrophenyl) phenylphosphonothioate) to p-nitrophenol. The activity of aminopyrine-N-demethylase, cytochrome P-450 and p-nitroanisole-O-demethylase in liver homogenates of rats receiving propoxur was measured. Liver microsomal detoxification enzymes were not induced by propoxur exposure.

Aminopyrine N-Demethylase↗
PubMed1983

Five-fingered hand associated with partial or complete tibial absence and pre-axial polydactyly. A kindred of 15 affected individuals in five generations.

A kindred of 15 affected individuals in five generations is described with autosomal dominant inheritance of bilateral five-fingered hand. Some of them had additional pre-axial polydactyly of the fingers or toes and some had partial or complete absence of the tibia. The range of expression of the gene is variable and genetic advice to these families must take account of the whole spectrum of defects. The function of both upper and lower limbs was improved by surgery. A distinction is drawn between the five-fingered hand shown in this family and the different deformity of a four-fingered hand with a triphalangeal thumb.

Abnormalities, Multiple↗
PubMed1983

Surgical reconstruction of the upper limb in traumatic tetraplegia. A review of 41 patients.

A review is presented of 41 patients with traumatic tetraplegia on whom reconstructive surgery of the upper limb was carried out. Twelve patients were followed up for more than 10 years after operation and the average period overall was seven and a half years. Tendon transfers were made with the aim of providing extension of the elbow or restoring a useful grasp or a combination of both. The assessment was carried out on four main aspects: the function of the elbow, the function of the hand, the ability to carry out the activities of daily living and the effect of the surgical reconstruction on the personal and social achievement of the patient.

Accidents, Traffic↗