Biomedical subjects
D W Mills
Publications and source records attributed to D W Mills.
Effects of Valsalva's manoeuvre on intraocular pressure.
We examined the effects of breath holding against a closed glottis (Valsalva's manoeuvre) on intraocular pressure (IOP) in four groups of volunteer subjects: 37 healthy young control subjects, 10 patients with chronic open-angle glaucoma, 11 age-matched control subjects and 8 glaucoma suspects. IOP was recorded by one person using a Digilab 30R/T Pneuma-Tonometer. Chart recordings of the IOP were measured independently by a second investigator. Recordings were taken before, during and 5 minutes after the seated subject exhaled into an aneroid manometer to a pressure of 25 to 35 cm H2O. There was marked variability in the individual responses to Valsalva's manoeuvre in all four groups, with substantial increases (to +9.5 mm Hg) and decreases (to -4.0 mm Hg) in IOP seen. The mean change in IOP during Valsalva's manoeuvre was a small, statistically insignificant decrease in all four groups. The mean change in IOP following Valsalva's manoeuvre was a larger, but still clinically small, decrease. The clinician should be aware of the individual variability in IOP changes with Valsalva's manoeuvre.
Depot triamcinolone-induced glaucoma.
The authors report two cases of recalcitrant ocular hypertension persisting 6 1/2 and 10 months following subconjunctival injections of 40 mg of triamcinolone acetonide. In both instances, the glaucoma resolved promptly after the whitish plaque of residual steroid was surgically removed.
Malignant glaucoma - the long and short of it.
Malignant glaucoma is a serious complication of surgery for angle-closure glaucoma. We describe three cases which exemplify important aspects of the onset and the management of the condition. It may develop soon after the original operation or only after many years, when it can be difficult to recognize. Simmon's approach to management is highly recommended, and intra-vitreous surgery is only employed if a five-day trial of intensive medical therapy fails.
Neovascular glaucoma in a university clinic.
A comparative survey of 100 consecutive clinic and private glaucoma patients was made in an attempt to determine the nature of these populations. Secondary glaucoma was found four times more frequently in the clinic group. The most common secondary form was neovascular glaucoma. This discouraging entity was reviewed with regard to etiology, pathogenesis, and management.
Visual field defects in pregnancy.
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Mesodermal dysgenesis of the anterior segment of the eye.
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The glaucomatocyclitis crisis.
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