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Biomedical subjects

D W Piraino

Publications and source records attributed to D W Piraino.

At least 19 recordsLinked to original sources
PubMed2000

The influence of the resolution and contrast on measuring the articular cartilage volume in magnetic resonance images.

The progression of OA in patients may be followed by measuring the volume of articular cartilage from MR images. We attempted to determine the reproducibility of volume measurements of articular cartilage made from magnetic resonance images of the knees and the dependence of the reproducibility on image resolution and contrast-to-noise. A fat-suppressed 3D technique was used to generate four image sets with different image resolution. Each patient was imaged twice to obtain image pairs at each resolution. To assess the dependence of reproducibility on noise we generated six image sets for each patient by adding noise to the original images and repeating the comparison. On each image set, the femoral, tibial, and patellar cartilage were outlined by a combination of computer and manual methods, and the images were used to calculate the volume of each cartilage plate. Comparing the coefficient of variance between the volume measurements made from the two visits, the volume measurements made from images with the highest resolution (0.275 x 0.275 x 1.0 mm) had the highest reproducibility. The high resolution images of the tibia and femur had the least partial-volume averaging and, as a result, better defined the boundaries between cartilage and adjacent tissues. A different trend was evident for the patella. For studies of osteoarthritis therapies, we recommend using MR images with the highest possible in-plane spatial resolution to provide the most reproducible volume measurements of knee cartilage.

Body Mass Index↗
PubMed1999

Selenium-based digital radiography versus conventional film-screen radiography of the hands and feet: a subjective comparison.

OBJECTIVE: The purpose of this study was to subjectively compare the visibility of normal anatomy of the hands and feet using selenium-based digital radiography versus conventional film-screen (100-speed) radiography. SUBJECTS AND METHODS: Digital and film-screen images of the hands and feet of 24 patients were obtained without an antiscatter grid using identical X-ray exposure. Each pair of images was evaluated independently by five experienced radiologists for visibility of normal anatomy using a six-point rating scale. Soft tissues, cortical bone, and trabeculae were evaluated. For each observer, "equivalence" was defined as a mean difference in image quality of less than 1 unit on the 0-5 scale used in the study. Paired t tests were also performed to determine whether the average visibility rating of one technique was statistically superior to that of the other at a .05 level of significance for each observer and at each anatomic landmark. RESULTS: In all categories, selenium-based digital images were rated equivalent to film-screen images by the five observers. Using the sum of the nine landmarks, four of the five observers rated the quality of selenium-based digital images superior to that of film-screen images. CONCLUSION: Subjective visibility of normal anatomy of the hands and feet using selenium-based digital radiography was similar to that achieved using conventional film-screen radiography.

Aged↗
PubMed1998

Imaging modalities for study of the distal ulnar region.

Judicious use of diagnostic imaging maximizes the diagnostic capabilities of the surgeon treating the distal radio-ulnar joint (DRUJ). A good clinical history and clinical examination are necessary to direct the selection of appropriate imaging studies. Plain radiographs are almost always the first imaging examination. More advanced imaging techniques are costly and may provide only limited information. This article discusses imaging modalities useful for assessment of the DRUJ and the area around it.

Arthralgia↗
PubMed1997

A new automated method for three-dimensional registration of MR images of the head.

A new technique for three-dimensional image registration was developed and tested using T1 and T2 weighted Magnetic Resonance image studies of the head. The method uses the fuzzy c-means classification algorithm for outlining the surface contours and then minimizes iteratively the mean squared value of the voxel per voxel weighted ratio of the two trilinearly interpolated cubic voxel volumes. A total of 200 two-dimensional and 240 three-dimensional registration experiments were performed and showed that the method is signal intensity independent, it has registration accuracy better than 1 degree for rotations and 1 voxel for translations and it is not affected by the deterioration in the imaging resolution for voxel sizes up to 1.8 mms.

Brain Diseases↗
PubMed1996

Accuracy of fat-suppressed three-dimensional spoiled gradient-echo FLASH MR imaging in the detection of patellofemoral articular cartilage abnormalities.

PURPOSE: To determine the accuracy of T1-weighted fat-suppressed (FS) three-dimensional (3D) fast low-angle shot (FLASH) magnetic resonance (MR) imaging for the detection of articular cartilage abnormalities of the patellofemoral joint. MATERIALS AND METHODS: Forty-one patients with suspected internal derangement of the knee were examined with a T1-weighted FS 3D FLASH sequence and subsequently underwent arthroscopy. The patellofemoral articular cartilage was graded blindly on both the MR and arthroscopic images with a modification of the Noyes classification scheme. RESULTS: For the detection of abnormal articular cartilage of the patellofemoral joint with the FS 3D FLASH sequence, sensitivity was 81%, specificity was 97%, and accuracy was 97%. Of the lesions detected on MR images, 77% were graded identically on MR and arthroscopic images. For the remaining 23%, MR imaging and arthroscopic ratings were within one grade of each other. CONCLUSION: T1-weighted FS 3D FLASH imaging is accurate for the detection and grading of articular cartilage abnormalities of the patellofemoral joint.

Adolescent↗
PubMed1996

Acromial morphology: relation to sex, age, symmetry, and subacromial enthesophytes.

PURPOSE: To evaluate acromial shape in relation to age, sex, symmetry, and presence of subacromial enthesophytes. MATERIALS AND METHODS: Three hundred ninety-four cadaveric scapulas were reviewed. Specimens were categorized by sex and age (age range, 20-89 years). Acromial morphology was typed according to the Bigliani classification: type I, flat; type II, curved; and type III, hooked. The presence and degree of subacromial enthesopathy was recorded. Selective radiographic correlation was obtained. RESULTS: The relative percentages of acromial types I, II, and III were 22.8% (90 acromions), 68.5% (270 acromions), and 8.6% (34 acromions), respectively. There was a greater percentage of type III in men (10.2% [21 of 205] vs 6.9% [13 of 189] and type I in women (27.5% [52 of 189] vs 18.5% [38 of 205]). There was no relationship between acromial type and age (P = .667). Enthesophytes were most common in type III (20 [59%] of 34 acromions) versus type II (115 [42.6%] of 270 acromions) and type I (22 [24%] of 90 acromions). Acromial morphology was symmetric in 135 (70.7%) of 191 pairs of acromions and asymmetric in 56 pairs (29.3%). CONCLUSION: Acromial shape does not vary significantly with age. It does, however, differ between sexes. The relative percentages of the types differ from previously reported values. Acromial shape tends to be symmetric. A trend between acromial type and the presence of enthesophytes is observed.

Acromion↗
PubMed1995

Localized anterior arthrofibrosis (cyclops lesion) after reconstruction of the anterior cruciate ligament: MR imaging findings.

OBJECTIVE: A localized form of anterior arthrofibrosis, the so-called cyclops lesion, has recently been reported to be a significant cause of loss of knee extension after reconstruction of the anterior cruciate ligament (ACL) of the knee. The purpose of this study was to characterize the MR appearance of this lesion. SUBJECTS AND METHODS: Five patients who had arthroscopic verification of a focal nodule of fibrous tissue in the intercondylar notch anterior to the reconstructed ACL (the cyclops lesion) and who had an MR examination after ACL reconstruction but before repeat arthroscopy and excision of the cyclops lesion were included in this study. The MR images were evaluated for the presence of soft tissue in the intercondylar notch anterior to the reconstructed ACL. If present, this tissue was graded as 1, 2, or 3, depending on its anterior extent along the femoral condyle. RESULTS: MR images of all five patients showed abnormal soft tissue with signal characteristics consistent with fibrous tissue anterior to the reconstructed ACL in the intercondylar notch. The abnormal tissue was grade 2 or 3 in all patients. CONCLUSION: MR imaging shows soft tissue with signal characteristics consistent with fibrous tissue anterior to the reconstructed ACL in the intercondylar notch in patients with localized anterior arthrofibrosis. Although the sensitivity and specificity of MR imaging for the cyclops lesion are yet to be determined, visualization of such fibrous tissue on MR images in a patient with clinical symptoms suggestive of localized anterior arthrofibrosis may be helpful in confirming the diagnosis.

Adult↗
PubMed1992

Medial malleolar stress fractures in seven patients: review of the clinical and imaging features.

Stress fractures of the medial malleolus were discovered in seven patients, five male and two female subjects aged 16-34 years. All except one were involved in running and jumping athletic activities. Gradual onset of pain over the medial malleolus occurred with repetitive activity. Focal intense increased uptake in the medial malleolus was present on bone scans. Conventional radiography and computed tomography demonstrated the presence of subtle fissures at the junction of the medial malleolus and the tibial plafond, and well-circumscribed lytic lesions were also seen in three patients. Two patients developed a complete fracture of the medial malleolus. Stress fractures of the medial malleolus should be suspected in patients involved in athletic and/or unusual activities who have experienced persistent and unexplained pain over the medial malleolus. Bone scans and radiographs should be obtained for diagnostic purposes in these patients.

Adolescent↗
PubMed1992

Diagnostic efficacy of digitized images vs plain films: a study of the joints of the fingers.

Four hundred fifteen finger joints from 30 patients were evaluated for the presence of joint-space erosion, narrowing, and degenerative spurring on plain films, low-resolution digitized images (1024 x 840 bytes x 12 bit matrix), and high-resolution digitized images (2048 x 1680 bytes x 12 bit matrix). Three hundred four joints were abnormal. Low- and high-resolution digital images were displayed on a 1K x 1K monitor with the ability to change level, window, orientation, and brightness. Five radiologists interpreted images. The presence or absence of each abnormality was determined by consensus of two skeletal radiologists who did not otherwise participate in the study. Receiver-operating-characteristic analysis was used to obtain an area and a true-positive rate at a 0.10 false-positive rate for each interpreter. Randomized block analysis of variance with interpreters as blocks was used to compare areas and true-positive rates among imaging techniques for each type of abnormality; no statistically significant differences were found. In conclusion, the efficacy of display of digitized images on high- and low-resolution modes is not significantly different from that of plain films in the detection of erosions, joint-space narrowing, or degenerative spurring in small joints of the hands.

Analysis of Variance↗
PubMed1991

Application of an artificial neural network in radiographic diagnosis.

The description of 44 cases of bone tumors was used by an artificial neural network to rank the likelihood of 55 possible pathologic diagnoses. The performance of the artificial neural network was compared with the performance of experienced (3 or more years of radiology training) residents and inexperienced (less than 1 year of radiology training) residents. The artificial neural network was trained using descriptions of 110 radiographs of bone tumors with known diagnoses. The descriptions of a separate set of 44 cases were used to test the neural network. The neural network ranked 55 possible pathologic diagnoses on a scale from 1 to 55. Experienced and inexperienced residents also ranked the possible diagnoses in the same 44 cases. Inexperienced residents had a significantly lower mean proportion of diagnoses ranked first or second than did the neural network. Experienced residents had a significantly higher proportion of correct diagnoses ranked first than did the network. Otherwise, a significant difference between the performance of the network and experienced or inexperienced residents was not identified. These results demonstrate that artificial neural networks can be trained to classify bone tumors. Whether neural network performance in classification of bone tumors can be made accurate enough to assist radiologists in clinical practice remains an open question. These preliminary results indicate that further investigation of this technology for interpretation assistance is warranted.

Bone Neoplasms↗
PubMed1991

Segmentation of magnetic resonance images using an artificial neural network.

Signal intensities from intermediate and T2 weighted spin echo images of the brain were used as inputs into an artificial neural network (ANN). The signal intensities were used to train the network to recognize anatomically-important segments. The ANN was a self-organizing map (SOM) neural network which develops a continuous topographical map of the signal intensities within the two images. The neural network segmented images demonstrated good correlation with white matter, gray matter, and cerebral spinal fluid (CSF) spaces. This technique was rated better than manual thresholding of the intermediate images, but not as good as manual thresholding of the T2 weighted images.

Brain↗
PubMed1990

Comparison of digital and conventional musculoskeletal radiography: an observer performance study.

Interpretations of 122 musculoskeletal radiographs were compared with interpretations of their digital counterparts at a resolution of 1,024 X 840 X 12 bits. Images were evaluated by four readers and included subtle and nonsubtle abnormalities and normal findings. Joint receiver operating characteristic (ROC) analysis results were averaged over all readers and demonstrated no statistically significant difference between the two imaging methods. High interobserver variability limited identifiable differences. Review of cases with subtle findings on the digital system at a resolution of 2,048 X 1,680 X 12 bits (2.5 line pairs per millimeter) revealed adequate visualization of the abnormality in every case. It is concluded that a resolution of 1,024 X 840 X 12 bits is adequate for the interpretation of many musculoskeletal abnormalities but that a resolution of 2,048 X 1,680 X 12 bits is needed for visualization of some subtle abnormalities.

Bone Diseases↗
PubMed1989

Problems in applying expert system technology to radiographic image interpretation.

A prototype expert system was developed to study the problems applying expert system technology to radiographic image interpretation. The Radiographic Image Interpretation System (RIIS) was developed on a microcomputer using Turbo Prolog, a low cost implementation of the prolog programming language. The present implementation of RIIS was developed to highlight potential problems in applying expert system technology in the evaluation of radiographic images. It was believed that the evaluation of this prototype expert system should include a large number of users unfamiliar with the program's use as this would probably be the case in clinical use of an image interpretation expert system. At present, the expert system deals with a limited domain of focal bony lesions. Twenty cases of pathologically proven bony lesions of varying difficulty were used to evaluate potential problems in the use of this expert system technology. RIIS, with the 20 sample cases, was presented as an exhibit at the 1987 Radiological Society of North America (RSNA) meeting to evaluate the potential problems with inexperienced users. These results were compared with those of experienced users. When a musculoskeletal radiologist, familiar with the programs use, provided the "proper description," the program averaged the correct diagnosis in the top five 80% of the time. During the program's use at the RSNA meeting, the program selected the correct diagnosis in the top five 22% of the time.

Bone Neoplasms↗
PubMed1989

Special diagnostic procedures in sports medicine.

In summary, there are a number of imaging procedures available to support the physician in his or her evaluation of sports injuries. Conventional radiographs remain the primary imaging examination. Specialized radiographic projections will often provide additional pertinent information. A fluoroscopic examination or conventional tomography may provide a cost-effective method of clarifying subtle post-traumatic changes. The use of the more sophisticated and costly imaging procedures should be reserved for those cases in which a diagnosis cannot be made with simpler technology. CT scanning, by virtue of its ability to image in the axial plane, has proved to be an effective method of documenting injuries particularly in complex bony anatomy such as the spine, wrist, elbow, and hips. CT arthrography provides diagnostic information about intra-articular structures. MRI is emerging as an excellent method of noninvasively imaging injuries to soft-tissue structures such as tendons, ligaments, and cartilage. The advancements in MRI technology that are projected for the future may expand the range of usefulness of this modality and decrease the current high cost of these procedures. Radionuclide scanning with Tc99m diphosphonate compounds has proved to be an efficient method of localizing subtle bone pathology and providing a "road map" for further analysis with additional imaging techniques. The cost-effective use of all of these imaging procedures is predicated on an understanding of their usefulness in the diagnosis of each clinical problem and the judicious use of each procedure to fit the needs of the individual patient.

Athletic Injuries↗
PubMed1985

The intranuclear cleft of the intervertebral disk: magnetic resonance imaging.

Three cadaver spines, 40 patients who were symptomatic for lumbar disk disease, and ten healthy subjects were examined by MR. T2 weighted spin echo images were used to evaluate the character of an intranuclear cleft. This cleft appears identical to annular tissue both on T2 weighted images and histologically. A 120 msec TE, 3 sec TR image was used to delimit the normal nucleus pulposus from the annulus. The incidence and age distribution of the cleft were calculated. An intranuclear cleft was present in all normal disks in both control and symptomatic subjects who were 30 years of age and older. If present in one disk, it was also present in 94% of the other disks in the same subject. This cleft represents a normal anatomic structure and appears to be a constant feature in subjects 30 years of age or older. Its absence, in the presence of an increased signal intensity within the disk, suggests a pathological process with a long T2 value, such as inflammation.

Adolescent↗