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Biomedical subjects

D W Unkle

Publications and source records attributed to D W Unkle.

9 recordsLinked to original sources

Successful donation and transplantation of multiple organs from a victim of cyanide poisoning.

Demand for viable human organs for transplantation continues to exceed the supply. To expand supply, the criteria for identification and management of suitable donors must continue to evolve. Poisoned patients are often excluded as potential organ donors due to perceived risks of transmittable agents and/or physiologically compromised organs. In this report, a patient succumbed after an intentional ingestion of cyanide and multiple pharmaceuticals. Donor organ viability was determined by lack of significant injury beyond the central nervous system. Following standard procurement procedures, the heart, liver, corneas, 16 skin grafts and 16 bone grafts were deemed suitable and successfully transplanted. All organ recipients were doing well eight months post transplantation. The focus of procurement personnel should be on tissue injury and not on the mere presence of clinical effect of a toxic agent. With the paucity of organs available, poison centers need to be cognizant of this dilemma when faced with a toxicologically compromised potential organ donor.

Adult↗

Blunt aortic trauma following deceleration in a seven year old.

Aortic injury following deceleration is an uncommon clinical entity in the pediatric population. Flexibility of the thoracic cage and marked tissue elasticity have been hypothesized as critical factors. Unfortunately, the scarcity of this phenomenon can lead to a lowered suspicion. We describe a case of blunt aortic injury following deceleration to raise the index of suspicion for this injury in the pediatric population.

Accidents, Traffic↗

Interpretation of the cervical spine X-ray: a simplified approach.

Because many nursing interventions require mobilization of the patient, cervical spine film interpretation should be a necessary tool of the critical care nurse. This article provides the fundamentals necessary for initial interpretation of the cervical spine, plus a review of the common radiographic views of the cervical spine, abnormalities, and a systematic approach to the interpretation of these studies.

Cervical Vertebrae↗

Myocardial contusion without creatine kinase--MB elevation.

Myocardial contusion after chest trauma remains one of the major complexities of trauma care today. Diagnostic methods such as 12-lead electrocardiography and echocardiography, as well as activity of the biochemical marker creatine kinase and the MB subfraction, have not been shown to be sensitive or specific indicators. We report a case of an intraoperatively proved myocardial contusion without creatinine kinase or creatine kinase MB elevation.

Adult↗

Trauma research nurse: a career option.

The critical care nurse has tremendous opportunities in clinical research projects. Until now, position descriptions that incorporated research into practice were scarce. This manuscript describes how to develop a trauma research nurse (TRN) position at your institution.

Career Choice↗

Mandatory HIV testing in critical care/emergency patients.

Testing for the presence of the human immunodeficiency virus (HIV) remains one of the most controversial issues of this decade. Among persons diagnosed to be HIV positive, social ostracism and exaggerated atypical behavior are common. The resulting impact on the delivery of healthcare services to the seropositive patient has raised many ethical and professional dilemmas. Discussion of HIV testing and the subsequent effects of seropositivity on the delivery of healthcare will be emphasized.

Attitude of Health Personnel↗