PubMed Health⌕ Search

Biomedical subjects

D W WOOLLEY

Publications and source records attributed to D W WOOLLEY.

At least 19 recordsLinked to original sources
PubMed1964

PREVENTION OF A MENTAL DEFECT OF PHENYLKETONURIA WITH SEROTONIN CONGENERS SUCH AS MELATONIN OR HYDROXYTRYPTOPHAN.

Mice made phenylketonuric from birth until maturity by continuous administration of phenylalanine plus tyrosine had a subnormal maze-learning ability which was largely prevented when serotonin congeners such as melatonin or 5-hydroxytryptophan were administered continuously from birth to maturity. These results were interpreted to mean that the mental failure of experimental phenylketonuria is attributable to the serotonin deficiency imposed by it in infancy.

5-Hydroxytryptophan↗
PubMed1962

Peptides required for the growth of Lactobacillus bulgaricus.

Jones, K. M. (The Rockefeller Institute, New York, N. Y.) and D. W. Woolley. Peptides required for the growth of Lactobacillus bulgaricus. J. Bacteriol. 83:797-801. 1962.-Lactobacillus bulgaricus 09 had an absolute requirement for growth for a suitable peptide, which was satisfied by trypsinized casein or hemoglobin. Digests of globin and the alpha and beta chains derived from it showed similar activity to hemoglobin digests. Each of four highly purified peptides of different amino acid composition isolated from the alpha chain of globin had activity. Each active peptide had seven or more residues; smaller peptides were inactive. The requirement for L. bulgaricus was not one for strepogenin because some substances with strepogenin activity for L. casei were not active for L. bulgaricus.

Caseins↗