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Biomedical subjects

D Warde

Publications and source records attributed to D Warde.

4 recordsLinked to original sources

Respiratory complications and hypoxic episodes during inhalation induction with isoflurane in children.

We have studied the incidence of respiratory complications and hypoxic episodes during inhalation induction with isoflurane in 75 healthy unpremedicated children. Problems occurred less frequently when 4% isoflurane in oxygen was used from the outset than with traditional techniques using nitrous oxide and a gradually increasing inspired vapour concentration. The improved results observed with the former method may be secondary to more rapid uptake of vapour so that the second stage of anaesthesia characteristic of anaesthetic ethers is shortened considerably.

Anesthesia, General

Oxygen saturation during inhalation induction with halothane and isoflurane in children: effect of premedication with rectal thiopentone.

Anaesthesia was induced by inhalation in 100 children using nitrous oxide in oxygen supplemented by either halothane or isoflurane, with or without rectal thiopentone premedication. Respiratory problems occurred more frequently in the unpremedicated isoflurane group, resulting in significant reductions in oxygen saturation. Premedication reduced the frequency of these complications, and oxygen saturation was usually maintained.

Administration, Rectal

Bacterial tracheitis.

Bacterial tracheitis is the term used to describe a severe infraglottic infection characterized by toxicity, brassy cough, inspiratory stridor, subglottic oedema and the presence of copious mucopurulent secretions in the trachea. It is an uncommon condition that requires prompt diagnosis and intensive medical therapy if significant morbidity and mortality are to be avoided. Since the condition was first described in 1979 approximately one hundred cases have been reported. In this paper we present four children with bacterial tracheitis to add to the current literature. Interestingly, one child was admitted on two separate occasions with the disease, an event not previously recorded. All patients underwent endoscopy which revealed findings typical of bacterial tracheitis in each case. None required tracheostomy though three required nasotracheal intubation. Post-endoscopy all were managed in the Intensive Care Unit. There were no fatalities or significant morbidity. The average duration of hospitalization was seven days.

Bacterial Infections