Biomedical subjects
Publications and source records attributed to D Wichmann.
Schistosomiasis a parasitic disease caused by trematodes is widely distributed in (sub-)tropical countries. Depending on the species the infection manifests clinically as gastrointestinal (preferentially Schistosoma mansoni and S. japonicum) or urinary (preferentially S. haematobium) disorders. Here we present an uncommon case of myeloradiculitis leading to bladder palsy and sensory loss at the lower limbs.
In an unmatched case-control study of 63 non-immune European patients with uncomplicated (n = 52) and complicated (n = 11) falciparum malaria, serum levels of N-terminal pro-brain natriuretic peptide (NT-proBNP), heart-type fatty acid-binding protein (H-FABP), myoglobin, troponin T and creatin kinase-muscle brain were compared. Elevated levels of NT-proBNP and H-FABP indicated myocardial impairment in complicated but not in uncomplicated falciparum malaria. The clinical impact of these findings remains to be evaluated. The pathophysiology of cardiac impairment in complicated falciparum malaria warrants further investigation.
Hemorrhagic fever with renal syndrome (HFRS), caused by different hantaviruses, is a distinct clinical syndrome endemic in several parts of Asia and Europe. However, the clinical picture can sometimes be indistinguishable from that of other infectious or noninfectious diseases. In this report we describe a clinical case, which is a rare occurrence but is a prime example of the difficulties in the diagnosis of HFRS in areas with a low prevalence of the disease.
Explore the source record for details and available documents.
The accumulated combination (X2 = 11.28 greater than 9.21) of Gm 1+ with Rh(CC) and of Gm 1-with Rh(cc) demonstrates the synteny of both markers on chromosome 1.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
663 breech deliveries between 1976 and 1985 at Hannover Medical School have been studied retrospectively. The overall frequency of breech deliveries was 4.5%. 6.1% were primigravid women. Comparisons were made to a group of deliveries with vertex presentation. Matched pairs were identical regarding the year of delivery, the method (vaginal delivery/caesarean section) and parity. 26.2% of breeches were born through the vagina. The frequency of vaginal deliveries after the 37th week of gestation ranged from 13.5% to 46.9% per year. For vaginal delivery the following prerequisites are defined at out institution: normal pelvic measures and physique, expected birth weight between 2500 g and 3500 g and informed consent. Until 1979 the frequency of vaginal deliveries ranged from 12% to 25%. Since 1980 an increasing number up to 45% was noted. For deliveries before the 38th week of gestation primary indicated caesarean section was preferred. The rate of maternal complications after caesarean section was high compared to vaginal deliveries (29.0% versus 8.6%; p less than or equal to 0.05). Also, these complications usually were more serious. Injuries of the newborn were more often observed following vaginal delivery than following caesarean section (7.5% versus 2.9%). No significant differences were found between the apgar scores after vaginal deliveries and caesarean sections. However, the percentage of reduced pH values was significantly higher after vaginal breech deliveries (57.5% versus 24.7%; p less than or equal to 0.05). No severe acidosis was observed. No difference was seen between the fetal outcome of deliveries from primiparous and multiparous women. Perinatal mortality according to WHO criteria was 1.1%.(ABSTRACT TRUNCATED AT 250 WORDS)
Isotope dilution analysis was used to quantitate 2-aminoacetophenone in wines exhibiting the so-called untypical aging off-flavor. d3-Aminoacetophenone was synthesized and used as isotopomeric internal standard. The method of quantitation was verified by several model experiments. In the off-flavored wines studied, amounts of 2-aminoacetophenone ranging from 0.7 to 12.8 micrograms/L were determined.