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Biomedical subjects

D Winter

Publications and source records attributed to D Winter.

At least 55 records · Page 3Linked to original sources

Renal failure does not impair the metabolism of morphine.

The pharmacokinetics of morphine were measured using gas chromatography-mass spectrometry (GCMS) with specific ion monitoring after the intramuscular administration of papaveretum to four patients with renal failure (one anephric) and three normals. The apparent t1/2 of absorption and t1/2 of elimination were significantly shorter in the patients with renal failure (P less than 0.05). Morphine glucuronides are eliminated slowly in these patients as expected. Renal failure does not impair the elimination of morphine.

Adult↗

[NAPROS--a semiautomatic, user-friendly anesthesia protocol system].

NAPROS is a semiautomatic inexpensive and easy to use anaesthetic record system. It is based on an ACORN (BBC-Model B) micro-computer that is linked to an non-invasive arterial pressure monitor (DINAMAP 845a) and an inhalation narcotic monitor (Engstroem EMMA) for automatic collection of the measured data. The following functions have been implemented: automatic registration of cardiovascular data and concentration of narcotic inhalation agents; input of drugs, fluid input or fluid output, laboratory values, events and comments of the anaesthetist; collection of administrative data and data concerning the preoperative state of the patient; graphic or numeric representation of fluid-balances; survey of all or selected drugs that have been administered up to that time; possibility for recalling dosage information for drugs and infusions; parallel printing of all collected data as a preliminary anaesthetic record; printing of a final anaesthetic report at the end of anaesthesia.

Anesthesiology↗

Dimensional change of acrylic resin tray materials.

Twelve commonly used acrylic resin tray materials were compared for linear curing shrinkage. Three of the 12 were found to expand slightly during the first few hours, which had the effect of reducing the net shrinkage. All trays, however, exhibited shrinkage during the 24-hour test period. Therefore, autopolymerizing acrylic resin tray materials should not be used for an impression the same day that they are made unless the tray is boiled as suggested by Pagniano et al. This agrees with research already completed even though the magnitude of shrinkage was considerably less than that reported in previous studies.

Acrylic Resins↗

[The anesthesia protocol].

It has long been recognised that it is necessary to document all medical actions. Every anaesthesia is to be documented on an anaesthetic transcript. Such a transcript has various purposes. It serves principally as an adequate patient-support, but also has administrative, statistical, scientific and forensic purposes. The transcript used at the Mannheim Klinikum is a printed form, which, apart from recording intra-operative events, also has room for entering pre- and post-operative test results. The recording of an anaesthetic transcript is an essential part of the duties of the anaesthetist in the clinic. Today, with the application of the most differentiated administrations of narcosis, it would seem that we can no longer do without a properly made anaesthetic transcript.

Anesthesia↗