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Biomedical subjects

D Wolke

Publications and source records attributed to D Wolke.

42 records · Page 3Linked to original sources
PubMed1988

Mortality, morbidity, growth and development of babies weighing 501-1,000 grams and 1,001-1,500 grams at birth.

During the five-year period, January 1980 to December 1984, 149 babies of extremely low birthweight (ELBW; 501-1,000 g) and 296 of very low birthweight (VLBW; 1,001-1,500 g) were admitted to King's College Hospital, Neonatal Intensive Care Unit. The survival rates were 51.7% and 82.8% respectively. There were more peri- and postnatal problems in the ELBW babies than the VLBW babies and these differences were highly significant. All surviving babies born between January 1980 and December 1982 were followed up until aged two. The ELBW children had a higher incidence of neuro-developmental sequelae than those of VLBW especially when both major and minor problems were considered. Their developmental quotients were lower at one and two years. Significantly more ELBW children were of short stature and low weight (less than 3rd centile). By two years of age the differences between ELBW and VLBW children in stature and mean DQ had lessened.

Child Development↗
PubMed1986

Prognosis of the very low birthweight baby in relation to gender.

The effects of gender on mortality and morbidity of all neonates weighing less than 1500 g admitted to King's College Hospital Neonatal Intensive Care Unit during 1980-82 (n = 271) were examined. Very low birthweight boys had a significantly higher mortality and more postnatal complications than girls. The higher incidence of respiratory distress syndrome and pulmonary interstitial emphysema in boys was associated with increased mortality in the first year. Surviving boys had significantly more problems, including lower Apgar scores at five minutes, more frequent apnoeic attacks and bradycardic episodes, transient tachypnoea, neonatal anaemia, and lower blood calcium and phosphate concentrations. Surviving children were followed up at 1 and 2 years of age. Development of boys at 1 year was significantly delayed compared with girls in all fields save locomotor. Although at 2 years some of the differences had diminished, those in language and personal social skills were more pronounced. More than twice as many boys as girls had major neurodevelopmental disorders.

Child Development↗
PubMed1986

["The screaming baby": Remarks on the article by Mangold and Fuchs ].

Mangold and Fuchs (1986) have pointed out that the topic "Screaming Babies" has only been cursorily addressed in the German literature. Some remarks and elaborations to the theoretical analysis by Mangold anf Fuchs are offered from the perspective of Developmental Psychology and Behavioural Paediatrics. Reviewing the anglo-american literature and our own research it is argued that infants cannot be viewed as "tabula rasa". Instead we conclude that they make a significant contribution to the interactions with the caretaker. It is emphasised that maternal descriptions of infant "difficultness" are reflections of both, infant behaviour and maternal emotional and cognitive state. In the single case we do not know that mother information reflects and we need to employ a multi-method multi-source approach for diagnosis. Finally suggestions for prevention and intervention are outlined based on our experiences in England.

Child Behavior↗
PubMedDate not supplied

[Premature rupture of fetal membranes, risk of infection and infant prognosis--a comparison of 2 regions].

The question to be answered was: Does premature rupture of membranes (PROM) and duration of PROM lead to increased mortality, neonatal and late morbidity and adverse cognitive developmental outcome? We present data of a bi-national cohort observation study in South Bavaria (SBy) and South Finland (SF). The sample included all children, who were admitted to a children's hospital (SBy N: 7505/70,600 live births; SF N: 1536/15,618), and some not transferred control infants (916 and 658, respectively). Obstetric details like PROM were obtained from perinatal records. Mortality and neonatal morbidity were recorded prospectively. Somatic, neurological and cognitive development was assessed at five and 20 months (corrected age), and final diagnosis of cerebral palsy (CP) and severe mental retardation was made at 56 months of age. Data were analysed separately for three gestational groups (< 32 (I), 32-36 (II), and > 36 weeks PMA (III)). PROM occurred more frequent in SBy than in SF and in both areas with preterm delivery. PROM irrespective of its duration had no adverse effect on mortality, morbidity, CP-rate or cognitive outcome of groups I and III in either SBy or SF. There was even a slightly lower mortality rate in extremely preterm infants after PROM. In SBy only, group II with PROM > 24 hours had a slightly increased incidence of CP. Unfavorable outcome was closely related to perinatal infections, which increased with duration of PROM. PROM and/or preterm labor occurred more often without than with inflammations of amnion and placenta. We conclude: PROM per se has no adverse effects on longterm outcome of special care infants, but it is closely associated with the developmental risk factors perinatal infections and, in particular, preterm birth. The prevention of ascending infections deserves further investigation, although such action may be beneficial lately to only a minority of individuals.

Brain Damage, Chronic↗
PubMedDate not supplied

Tooth eruption in failure-to-thrive infants.

The purpose of this study was to determine whether differences existed between the numbers of erupted teeth of infants who were failing to thrive and their controls. The results suggest a relationship does exist.

Age Factors↗