Pulmonary Mycobacterium avium intracellulare infection in eosinophilic granuloma.
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Biomedical subjects
Publications and source records attributed to D de Berker.
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Using information from a light microscope integrated with a computer, we quantified the variation in node and internode dimensions in monilethrix. We combined this with rate of growth measurements in individual hairs to make the following conclusions. There is considerable variation of node and internode configuration within single hairs. Hairs from the same scalp, sampled at the same time show no mutual coordination of node-internode formation, even when different growth rates are taken into account. There is no apparent correlation between the day-night cycle and the node-internode rhythm. The follicular expression of monilethrix appears largely independent of unifying systemic influences.
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Eighty-six patients with chronic cutaneous lupus erythematosus were examined. Twelve of these also suffered from systemic lupus erythematosus. The mean duration of the disease was 15.1 years. Fifty-seven percent of patients (49/86) had scarring of some kind producing destruction and deformity; 47% (41/86) had scarring of glabrous surfaces and 35% (30/86) had scarring alopecia; 35% (30/86) were also suffering from pigmentary disturbance. The details and treatment of these and other non-scarring sequelae are discussed.
We report a childhood case of monilethrix in which oral etretinate was given. Clinically, the cosmetic benefit was marginal. However, of note was that there was an increase in hair length with loss of beading along the shaft of these hairs. The background scalp appearance of keratosis pilaris persisted in these areas. This suggests that the beading alone is influenced by etretinate and is not solely an artefact secondary to the hyperkeratotic condition at the follicular opening.
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