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Biomedical subjects

D von Domarus

Publications and source records attributed to D von Domarus.

At least 55 records · Page 3Linked to original sources
PubMed1982

[Necrosis of iris and ciliary body--a histopathological study].

Necrotic foci within the iris and ciliary body were present in 104 eyes examined at the histopathological laboratory of the University Eye Clinic, Hamburg. Three different aetiological mechanisms were found: 1) Vascular acute glaucoma, diminished arterial supply, or radiogenic occlusive vasculitis can lead to ischaemic infarction. 2) Inflammatory: direct contact with the noxious agent can lead to cell death, either via liberation of toxines and enzymes--usually bacterial--or due to direct cytotoxic effect, in case of viruses. Both can further cause cell death via immunological mechanisms. Intraocular suppurative bacterial infections predominate in this group. 3) Traumatic and operative: tissue damage is caused by mechanical or thermal injury. Besides accidental trauma, uveal necrosis also occurs frequently after surgical coagulation or dialysis of the ciliary body for glaucoma. The sequelae of iris and ciliary body necrosis depend on the extent of the damage. Small necrotic areas are followed by scarring, which has no injurious consequences on visual function. Widespread necrosis, on the other hand, is complicated by immediate atrophia bulbi or secondary angle-closure glaucoma with or without rubeosis iridis.

Ciliary Body↗
PubMed1982

[Long-term results after goniotomy (author's transl)].

Between 1961 and 1968 140 goniotomies were performed at the Department of Ophthalmology, University of Hamburg. The condition of 72 eyes was evaluated and 41 eyes were re-examined. The average intraocular pressure was 33 mmHg preoperativly and only 20 mmHg 13 to 20 years after the goniotomy procedure. Patients from this group with buphthalmus had an even lower pressure of only 17.6 mmHg. Pressure regulation was achieved in 85% of the evaluated eyes by one or more operations, in conjunction with drug therapy in some instances. In 18 of the 41 eyes a satisfactory result was achieved after a single goniotomy procedure. In 15 of the 41 eyes visual acuity was 0.3 or better with normal pressure. The risk of postoperative amblyopia is mentioned.

Adolescent↗
PubMed1981

[Some correlations between ultrasonographic and histopathologic findings in malignant melanoma of the choroid (author's transl)].

The ultrasonographic findings in 39 cases of malignant melanoma of the choroid has been correlated with histopathological results. Tumors with hemorrhages and/or necrosis showed a lower reflectivity than those with a higher amount of connection tissue. B-scan ultrasonography was found to be reliable for the measurement of the extent of the tumor in all three dimensions.

Choroid Neoplasms↗
PubMed1981

Treatment of bilateral choroidal malignant melanoma.

A history is presented of a 40-year-old male patient suffering from bilateral choroidal melanoma. Both eyes were treated with 106Ru/106Rh beta-irradiation. 2 years later one eye was enucleated because of radiogenic central vein thrombosis with secondary glaucoma. Histologically the tumor cells showed radiogenic damages and there were no signs of a new tumor growth. The other eye, however, is still functioning 6 years later with a visual acuity of 1.0.

Choroid Neoplasms↗
PubMed1980

[Endothelialization of the anterior chamber: clinical aspects and histopathology (author's transl)].

Out of 1800 enucleated globes histologically examined at Hamburg University Department of Ophthalmology there was endothelialization of the anterior chamber in 77. In all these cases secondary angle closure was also found. Proliferation of endothelial cells is triggered by peripheral anterio synechiae, mechanical irritation of the cornea, and/or damage to the endothelium caused by inflammation of the anterior segment. The histological picture correlated with the whitish-grey membrane seen gonioscopically covering the angle recess and the anterior iris surface. Surgery of the ciliary body appears to be the only effective procedure.

Adolescent↗
PubMed1979

[Recurrent iritis caused by persistent hyperplastic primary vitreous body with pseudophakia lipomatosa].

In a 27-year-old patient a microphthalmic eye with congenital cataract was enucleated because of persistent recurrent iridocyclitis with a secondary glaucoma. Histopathological examination has shown a lens shrunken up to the capsule and a retrolental typical fatty tissue (pseudophakia lipomatosa). Secondary angle closure glaucoma and chronic uveitis seem to be due to an untreated hypermature cataract. These findings and the clinical course are suggesting that the opaque lens and the persistent hyperplastic vitreous body should have been operated in order to avoid complications.

Adipose Tissue↗
PubMed1979

[Report on corneo-scleral ulceration after cataract extraction (author's transl)].

A case of corneo-scleral ulceration beginning 4 months after uncomplicated cataract-extraction is reported on. Neither conservative nor operative treatment was able to stop the ulceration, so that enucleation was necessary. The clinical picture and serological and ophthalmopathological findings are shown. The probably immunological aetiology is discussed.

Aged↗
PubMed1979

[Conjunctival myxomas (author's transl)].

Myxomas are rare mesenchymal tumors appear everywhere in the body, but occur very seldom in orbital or subconjunctival regions. Clinical and histopathological demonstration of two cases of epibulbar myxoma and discussion of possible pathogenetic mechanisms.

Aged↗
PubMed1978

[Metastases of carcinoma of the breast to the choroid in the female (author's transl)].

Combined hormonal and cytostatic treatment was undertaken in eight women with choroid metastases from a breast carcinoma, in all cases only part of a more generalised - in most cases visceral - metastasization. If there are additional metastases those to the choroid do not require primary radiotherapy, as the treatment resulted with the remission in six of eight of the patients (mean duration of 12 months) and a rise in visual acuity in five of the six indicated. If remission is not achieved with combined hormonal and cytostatic treatment, radiotherapy to the choroid metastases in combination with polychemotherapy can be undertaken as second best.

Adult↗
PubMed1978

[Eosinophilic granuloma of the conjunctiva].

The histology of a case of dermal and conjunctival eosinophilic granuloma in a 74-year-old female patient is described. The aetiology could not be established until now. The differential diagnosis of atypical histiocytosis X, eosinophilic leukaemoid and eosinophilia persistens is discussed.

Aged↗
PubMed1978

Adenoma of the iris pigment epithelium.

The clinical, fluorescein angiographical and histopathological findings of a mucous-producing adenoma apparently arising from the iris pigment epithelium is reported, and the differential diagnosis is discussed. Benign epitheliomas of the iris pigment epithelium are exceedingly rare and are usually heavily pigmented tumors. This appears to be the second documented case of a nonpigmented benign epithelioma of the iris.

Adenoma↗
PubMed1978

[Mucoepidermoid carcinoma of the conjunctiva (author's transl)].

This is a report on a mucoepidermoid carcinoma in a 69 year old male, a rare occurence, originating clinically from the conjunctiva of the globe. The microscopic features, the pathogenesis and the histological differentiation are discussed.

Adenocarcinoma, Mucinous↗