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Biomedical subjects

Délio Marques Conde

Publications and source records attributed to Délio Marques Conde.

9 recordsLinked to original sources

Pseudomamma on the foot: an unusual presentation of supernumerary breast tissue.

A 22-year-old woman sought medical care for a lesion in the plantar region of her left foot, a well-formed nipple surrounded by areola and hair. Microscopic examination of the dermis showed hair follicles, eccrine glands, and sebaceous glands. Fat tissue was noted at the base of the lesion. Clinical and histopathologic findings were consistent with the diagnosis of supernumerary breast tissue, also known as pseudomamma. To our knowledge, this is the first report of supernumerary breast tissue on the foot.

Adult↗

[Constipation in postmenopausal women].

OBJECTIVES: To investigate the prevalence and factors associated with constipation in postmenopausal women and evaluate the level of agreement between different diagnostic criteria. METHODS: A cross-sectional study was conducted with 100 postmenopausal women more than 45 old. The Rome II criteria, stool frequency per week and patient self-evaluation were the diagnostic criteria applied. Social demographic and clinical characteristics with their descriptive analysis were assessed. Subsequently, kappa (ê) statistics was used to assess the level of agreement between diagnostic criteria. The association between constipation and its possible determinants was studied by bivariate and multivariate analyses, using the prevalence ratio (PR). The confidence interval was set at 95% (95% CI). RESULTS: The mean age of participants was 58.9+/-5.9 years (range, 46-76 years). The prevalence of constipation was 47%, 37% and 26%, according to patient self-evaluation, the Rome II criteria and < 3 bowel movements per week, respectively. The best agreement found was between patient self-evaluation and the Rome II criteria (k: 0.63; 95% CI: 0.48-0.78). After multivariate analysis, the history of perianal surgery (PR: 2.69; 95% CI: 1.03-7.01), according to the Rome II criteria; the presence of hemorrhoids, according to stool frequency (PR: 2.53; 95% CI: 1.16-5.51) and patient self-evaluation (PR: 1.78; 95% CI: 1.01-3.15) were associated with constipation. CONCLUSIONS: Prevalence of constipation in postmenopausal women was high. Agreement between diagnostic criteria ranged from moderate to good. History of perianal surgery and presence of hemorrhoids were associated with constipation.

Aged↗

Factors associated with quality of life in a cohort of postmenopausal women.

OBJECTIVE: To evaluate quality of life (QOL) and identify its associated factors in a cohort of postmenopausal women who had not received hormone therapy. METHODS: A cross-sectional study was conducted among 81 postmenopausal women who had not used hormone therapy in the last six months. Sociodemographic and clinical characteristics, in addition to the prevalence of menopausal symptoms, were evaluated. QOL was assessed by the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) questionnaire, which may be condensed into two summaries: Physical Component Summary and Mental Component Summary. Generalized linear models were used to analyze the data, allowing the identification of factors affecting QOL, adjusting for confounding variables. RESULTS: The mean (+/-standard deviation) age of the participants was 58.1 +/- 4.7 years. The most prevalent symptoms were nervousness (67%) and hot flushes and sweating (51%). Factors associated with poorer QOL were sweating, palpitations, nervousness (physical component), and dizziness, nervousness, depression, insomnia and dyspareunia (mental component). CONCLUSION: We observed that menopausal symptoms negatively affected the physical and mental components of QOL in postmenopausal women.

Aged↗

Fibroadenoma in axillary supernumerary breast: case report.

CONTEXT: Supernumerary breast tissue may be affected by the same diseases and alterations that compromise topical breast tissue. Nevertheless, reports of fibroadenoma in supernumerary breast tissue in the axillae are rare. OBJECTIVE: To describe a case of fibroadenoma in an axillary supernumerary breast. DESIGN: Case report. CASE REPORT: A 39-year-old woman was referred to the gynecology and obstetrics outpatient clinic at Hospital Estadual Sumaré, complaining of bilateral axillary masses. The patient reported cosmetic problems and local pain and discomfort. On physical examination, alterations compatible with bilateral axillary accessory breasts, without palpable nodules, were observed. Supplementary examinations (mammography and ultrasonography) revealed a 1.1 cm mass in the right axillary breast. The patient underwent resection of the supernumerary breasts and histopathological examination revealed fibroadenoma of the right axillary breast tissue.

Adult↗

[Prevalence and factors associated with intestinal constipation in postmenopausal women].

BACKGROUND: Constipation occurs more frequently in the female population and it becomes more prevalent with increasing age. There are few studies that have assessed the prevalence of constipation in postmenopausal women. AIM: To investigate the prevalence and factors associated with constipation in postmenopausal women. PATIENTS AND METHODS: A cross-sectional study of postmenopausal women aged over 45 years was conducted. It included 100 women who sought medical attention at the Menopause Outpatient Facility at the State University of Campinas (UNICAMP), Campinas, SP, Brazil, between March, 2003 and January, 2004. The prevalence of constipation was assessed according to the Rome II criteria. Sociodemographic and clinical features of these patients were studied. Physical examinations were performed to evaluate genital dystopias and anal sphincter tone. Statistical analysis was performed by using the mean, standard deviation, median, relative and absolute frequencies and by using the prevalence ratio with a 95% confidence interval and multiple logistic regression. RESULTS: The mean age of the participants was 58.9 +/- 5.9 years and the mean age was 47.5 +/- 5.4 years at menopause. The prevalence of constipation was 37%, the most common symptom being excessive straining when defecating (91.9%), followed by a feeling of incomplete evacuation (83.8%), hard or lumpy stools (81.1%), less than three bowel movements per week (62.2%), sensation of anorectal obstruction during defecation (62.2%) and digital maneuvers to facilitate defecation (45.9%). Bivariate analysis showed that anal sphincter tone and the history of perianal surgery were factors associated with constipation. After applying multiple regression analysis, the history of perianal surgery was significantly associated with constipation (prevalence ratio: 2.68; 95% confidence interval: 1.18-6.11). CONCLUSIONS: The prevalence of constipation in postmenopausal women was high. The history of perianal surgery was significantly associated with constipation, even when the influence of other variables were taken into consideration.

Brazil↗

Impact of the preservation of the intercostobrachial nerve in axillary lymphadenectomy due to breast cancer.

This study evaluated the relationship between preservation of the intercostobrachial (ICB) nerve and pain sensitivity of the arm, the total time of the surgery, and the number of dissected nodes in patients submitted to axillary lymphadenectomy due to breast cancer. An intervention, prospective, randomized, and double blind study was performed on 85 patients at the State University of Campinas, Brazil, from January 1999 to July 2000. The patients were divided into two groups, according to whether the ICB nerve was preserved or not. The surgeries were performed by the same surgeons, utilizing the same technique. The postoperative evaluations were performed at 2 days, 40 days, and 3 months. The pain sensitivity of the arm was evaluated through a specific questionnaire (subjective evaluation) and through a neurologic examination (objective evaluation). The surgical technique presented a feasibility of 100% and preservation of the ICB nerve was related to a significant decrease in the pain sensitivity of the arm, both in the subjective and objective evaluations. After 3 months, in the subjective evaluation, 61% of the patients were asymptomatic in the ICB nerve preservation group, with 28.6% in the nerve section group (p<0.01). In the objective evaluation, 53.7% of the patients presented normal neurologic examination in the ICB nerve preservation group, with 16.7% in the nerve section group (p<0.01). No significant difference was observed in the total time of the surgery (p=0.76) and the number of dissected nodes between the two groups (p=0.59). Local relapse was not observed in any group after 36 months of follow-up. These data support that preservation of the ICB nerve is feasible and leads to a significant decrease in the alteration of pain sensitivity of the arm, without interfering with the total time of the surgery, the number of dissected nodes, and local relapse rate.

Axilla↗

Quality of life in Brazilian breast cancer survivors age 45-65 years: associated factors.

The objectives of this study were to evaluate quality of life (QOL) and identify its associated factors in climacteric women with a history of breast cancer. A cross-sectional study was performed including 75 breast cancer survivors age 45-65 years who had undergone complete oncologic treatment and nonusers of hormone therapy or tamoxifen in the last 6 months. Sociodemographic and clinical characteristics in addition to the prevalence of climacteric symptoms were evaluated. QOL was evaluated by the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) questionnaire, including eight components that can be condensed into two summaries: a physical component summary (physical functioning, role-physical, body pain, general health) and a mental component summary (vitality, social functioning, role-emotional, and mental health). Generalized linear models were used to analyze the data, allowing the identification of factors affecting QOL, adjusting for confounding variables. The mean age of the participants was 53.1+/-5.9 years. Breast cancer survivors reported good QOL. The most prevalent symptoms were nervousness (69%) and hot flashes (56%). Factors associated with poorer QOL were dizziness, postmenopausal status, and breast-conserving therapy (physical component), as well as insomnia and being married (mental component). In conclusion, participants demonstrated good QOL. We identified factors that may influence QOL in women with breast cancer, highlighting being married, climacteric symptoms, postmenopausal status, and breast-conserving therapy. Given the impact of these factors, health professionals and patients must discuss choices for alleviating climacteric symptoms and explanations for the potential repercussions of breast cancer treatment.

Aged↗

[Fecal incontinence in postmenopausal women: prevalence, severity and associated factors].

BACKGROUND: Fecal incontinence occurs more frequently in the female population and it becomes more prevalent with increasing age. There are few studies that have assessed the prevalence and severity of postmenopausal women. AIMS: To investigate fecal incontinence. PATIENTS AND METHODS: A cross-sectional study was performed on 100 postmenopausal women over the age of 45. Sociodemographic and clinical characteristics were evaluated, and a descriptive analysis of these characteristics was carried out. The prevalence of fecal incontinence was estimated. St. Mark's incontinence score was applied to study the severity of symptoms associated with fecal incontinence. The score was then categorized according to the tertile and symptom severity was classified as mild, moderate or severe incontinence. Bivariate and multivariate analyses were used to study the association between fecal incontinence and its likely determinants, employing the prevalence ratio. Confidence interval was set at 95%. RESULTS: The mean age of the patients was 58.9 +/- 5.9 years (range, 46-76 years). The prevalence rate was 15% for fecal incontinence. Of incontinent patients, 60% had mild incontinence. After multivariate analysis, factors associated with fecal incontinence was history of forceps delivery (prevalence ratio: 7.80; 95% confidence interval:2.38-25.55). CONCLUSIONS: The prevalence of fecal incontinence was high in postmenopausal women. Data suggest that most women presented mild fecal incontinence. The history of forceps delivery was associated with fecal incontinence.

Aged↗