Biomedical subjects

Dale F Hay

Publications and source records attributed to Dale F Hay.

6 recordsLinked to original sources

PubMed2006

Agreement between maternal report and antenatal records for a range of pre and peri-natal factors: the influence of maternal and child characteristics.

BACKGROUND: Events during pregnancy and labour may influence the future health and well-being of offspring. Many studies rely on maternal reports of pre and peri-natal factors. Both maternal and child characteristics may potentially influence the reliability and accuracy of maternal recall. However, this has not been previously examined. AIMS: To examine agreement between information from maternally reported questionnaires and medical records for a range of pre and peri-natal factors. To examine whether maternal and child characteristics influence the level of agreement with medical records. METHODS: A survey of women who had school aged children born following in vitro fertilization (IVF) was carried out. Mothers completed a postal questionnaire booklet which included the Lewis and Murray scale which asks about antenatal and obstetric complications and the Strengths and Difficulties Questionnaire which assesses child behaviour problems. Antenatal case notes were also reviewed. Multi-centre ethical approval was obtained. Complete data were available for 126 women. RESULTS: The agreement between maternal report and medical records was very good for the majority of outcomes examined (infant birth weight, infant admission to special care baby unit, method of delivery, smoking during pregnancy, high blood pressure/oedema during pregnancy). Exceptions were length of labour and alcohol use during pregnancy. However, alcohol use during pregnancy was not routinely recorded in medical records. Maternal characteristics did not substantially influence level of agreement for the majority of outcomes examined. Exceptions were that agreement for length of labour was better in women with more educational qualifications and that agreement for pre-natal smoking was worse in women from higher socio-occupational groups. There was little evidence that child behaviour problems influenced the level of agreement between maternal recall and medical records. CONCLUSIONS: For the majority of pre and peri-natal events examined, mothers can provide accurate reports in comparison to information from medical records.

Alcohol Drinking↗

PubMed2005

Twins born following fertility treatment: implications for quantitative genetic studies.

The rate of multiple births is substantially elevated in women who have had assisted reproduction treatment (ART; approximately 26%) compared to the general population ( approximately 1%), and these offspring are usually included in twin studies. Several studies have attempted to identify possible consequences of undergoing ART on the subsequent offspring. However, most studies have only included singleton births. We first examined whether twins born by ART differed from other twins on measures of childhood psychopathology, putative risk factors and correlates, and secondly tested for differences in the degree of twin similarity for available outcome measures. From a population-based twin sample, 101 families with dizygotic (DZ) twins conceived via ART were identified and compared with 1073 naturally conceived (NC) control DZ twin pairs. Analyses performed were (1) univariate and multivariate comparisons of between-group mean differences; and (2) comparison of twin 1-twin 2 correlations between the groups. The groups differed significantly on demographic factors (parental age, family size and social class) and pregnancy variables (smoking during pregnancy and birthweight) but did not differ on family conflict scores or in the frequency of obstetric complications. Family cohesion was higher in the ART group but this was accounted for by demographic factors. For child psychopathology there was a difference between the groups only for teacher-rated ADHD (Attention Deficit Hyperactivity Disorder). Differences were also found between groups for twin correlations. The differences found between ART and NC twins on group means and twin correlations suggest that researchers should be aware that including ART twins may influence results from twin studies.

Antisocial Personality Disorder↗

PubMed2004

Peer relations in childhood.

We present a developmental model that describes normal peer relations and highlights processes that underlie the emergence of problems with peers in childhood. We propose that children's relationships with peers begin in the first years of life, with stable individual differences and preferences for particular peers emerging by three years of age. Social skills that facilitate peer relationships consolidate in the preschool years, during which time peer groups become structured with respect to friendship groups, gender, and dominance relations; some children begin to be rejected by their peers. In later childhood some children develop entrenched problems with peer relationships, in terms of loneliness, bullying and victimisation. Underlying cognitive and emotional processes that facilitate successful peer relationships at all ages are identified, and the extent to which peer relations play a causal role in the genesis of disorder is evaluated. A review of the evidence suggests that, rather than a simple pathway from problematic peer relations to disorder, there is a reciprocal relationship between children's problems with peers and their psychological problems from infancy to adolescence.

Affect↗

PubMed2004

The prediction of disruptive behaviour disorders in an urban community sample: the contribution of person-centred analyses.

BACKGROUND: Variable- and person-centred analyses were used to examine prediction of middle childhood behaviour problems from earlier child and family measures. METHOD: A community sample of 164 families, initially recruited at antenatal clinics at two South London practices, was assessed for children's behaviour problems and cognitive ability, maternal mental health, and the family environment when the children were 4 years old. At age 11, children, mothers, and teachers reported the child's disruptive behaviour, and mothers and children were interviewed to identify cases of disruptive behaviour disorders (DBD). RESULTS: Neither social class nor ethnicity predicted the child's disruptive behaviour at age 11. Rather, path analyses and logistic regression analyses drew attention to early behavioural problems, maternal mental health and the child's cognitive ability at 4 as predictors of disruptive behaviour at age 11. Cluster analysis extended these findings by identifying two distinct pathways to disruptive symptoms and disorder. In one subgroup children who showed intellectual difficulties at 4 had become disruptive by 11. In a second subgroup mothers and children both showed psychological problems when the child was 4, and the children were disruptive at age 11. The person-centred approach also revealed a high-functioning group of cognitively able 4-year-olds in supportive environments, at especially low risk for DBD. CONCLUSIONS: Combining variable- and person-centred analytic approaches can aid prediction of children's problems, draw attention to pertinent developmental pathways, and help integrate data from multiple informants.

Attention Deficit and Disruptive Behavior Disorder↗

PubMed2003

Pathways to violence in the children of mothers who were depressed postpartum.

The impact of postnatal depression on a child's risk for violent behavior was evaluated in an urban British community sample (N=122 families). Mothers were interviewed during pregnancy, at 3 months postpartum, and when the child was 1, 4, and 11 years of age. Mothers, teachers, and children reported on violent symptoms at age 11. Structural equation modeling revealed that the child's violence was predicted by the mother's postnatal depression even when her depression during pregnancy, her later history of depression, and family characteristics were taken into account. Violence was associated with symptoms of attention-deficit/hyperactivity disorder and problems with anger management. Children were most violent if mothers had been depressed at 3 months and at least once thereafter.

Adolescent↗

PubMedDate not supplied

Prosocial development in relation to children's and mothers' psychological problems.

The study tested whether children's prosocial behavior was negatively or positively related to children's and mothers' psychological problems. Participants were 149 London families when mothers were pregnant and followed up in infancy and at ages 4 and 11. Children's cooperation at 4 and general prosocial tendencies at 11 were negatively associated with externalizing problems but unrelated to internalizing problems. A subgroup of children who were more prosocial than average expressed clinically significant worries about family members. Maternal depression decreased prosocial behavior in the eyes of adults, but children of depressed mothers saw themselves to be prosocial. Early cooperation protected children against later risk for externalizing problems, even when their early behavioral problems were taken into account.

Child↗