PubMed Health⌕ Search

Biomedical subjects

Daniel Val

Publications and source records attributed to Daniel Val.

5 recordsLinked to original sources
PubMed2006

Ectopic epididymal tissue in appendix testis.

Aberrant epididymal tissue is uncommon and may be associated with an undescended testis. To the best of our knowledge, aberrant epididymal tissue has not been described in a testicular appendix. We report the case of a 7-year-old boy with left cryptorchidism who underwent a homolateral orchidopexy. At operation, the surgeon removed a pedunculated appendix testis containing an epididymal heterotopia. This Wolffian-derivative tissue was confirmed by the diffuse strong CD10 reactivity of the luminal border of the epithelial cells. Awareness of this aberrant tissue avoids misinterpretation as a transected functional reproductive structure.

Biomarkers↗
PubMed2006

Isolated (localized) idiopathic granulomatous (giant cell) vasculitis in an intramuscular lipoma.

Isolated (localized) idiopathic granulomatous vasculitis (IGV) is an uncommon, heterogeneous, and poorly defined group of disorders characterized by infiltration of the arterial wall caused by compactly grouped mononuclear phagocytes, with or without giant cells, in segmental distribution. We report on a 55-year-old woman with IGV limited to an intramuscular lipoma of the left thigh. The vasculitis was identified incidentally upon microscopic examination of the removed tumor. The IGV was centered on two medium-sized arteries, accompanied by narrowing of the lumens, and not associated with secondary changes such as infart or postinfart fibrosis. The inflammatory infiltrate was rich in T-lymphocytes and macrophages, with the presence of giant cells. The patient was asymptomatic and well in a follow-up period of 2 months, during which she was not treated. To our knowledge, this is the first report of lipoma involvement in localized IGV. It is important to distinguish cases of isolated intratumorous IGV from systemic disease, because the latter implies a poor prognosis and requires an aggressive treatment.

Antigens, CD↗
PubMed2002

Cutaneous lipomatous neurofibroma.

We report a cutaneous lipomatous neurofibroma on the skin of the left-side parietal area of approximately 9 months' duration in a 67-year-old woman. The regular distribution of adipose tissue throughout the lesion suggested that fat was an integral part of the tumor, not a metaplastic or degenerative process. To our knowledge, this type of lesion has not been documented. The main differential diagnosis embraces neurocristic cutaneous hamartoma, lipoma and its variants, cutaneous meningioma, and neural nevus with fat replacement. We propose that lipomatous neurofibroma of the skin is caused by aberrant development of adipose tissue in a neurofibroma. The lesion originated as pluripotential neural crest cells after migration. This acquired lesion could arise from local stem cells. The old suggestion that neuroectoderm is capable of mesenchymal differentiation may be relevant to the histogenesis of this neoplasm.

Adipose Tissue↗
PubMedDate not supplied

Incidental detection of an asymptomatic papillary fibroelastoma on a control biopsy of a heart transplant recipient.

BACKGROUND: Papillary fibroelastoma (PFE) of the right ventricle is a rare lesion. This tumor has not been described in the heart of a cardiac transplant recipient. METHODS AND RESULTS: We report a 42-year-old woman suffering from chronic ischemic cardiopathy who underwent an orthotopic cardiac transplantation. Five years after surgery, the control two-dimensional echocardiography showed no abnormalities. At this time, the programmed endomyocardial biopsies of the right ventricle included a 2-mm lesion that was diagnosed as PFE. To our knowledge, only a previous case of this tumor has been detected at random in a control cardiac biopsy. Differential diagnosis includes chordae tendinae removed at the time of cardiac sampling, Lambl excrescence, and myxoma. CONCLUSION: PFE can arise in a cardiac transplant recipient and may be detected on a random programmed biopsy.

Adult↗