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David A Steven

Publications and source records attributed to David A Steven.

5 recordsLinked to original sources
PubMed2006

Morbidity associated with the use of intracranial electrodes for epilepsy surgery.

BACKGROUND: Invasive monitoring for the investigation of medically intractable epilepsy may be associated with undesirable morbidity. We performed a review of our recent experience to determine the incidence of major complications. METHODS: We reviewed the clinical records of all patients who underwent invasive EEG monitoring at our institution between 2000 and 2004. RESULTS: One-hundred and sixteen patients (57 males, 59 females) with a mean age of 32 years of age underwent intracranial placement of electrodes for epilepsy surgery investigation. Subdural strips were placed in 115 patients with a mean of eight strips per patient. Subdural grids were inserted in 11 patients and depth electrodes in five. Fourteen of the 15 patients with grids or depth electrodes also had strips. Coverage was unilateral in 37 patients and bilateral in 79 patients. Electrodes were placed over the frontal lobe in 78 cases, temporal in 93, parietal in 24, and occipital in 27 patients. The average duration of investigation was 12.3 days (range 3-29). The evaluation led to the performance of a surgical resection in 85 patients (74%). Complications were seen in four patients with subdural strips (3%), and in two patients with grids (13%), characterized by clinical infection, intracranial hemorrhage, aseptic meningitis, transient neurological deficits, and status epilepticus. Mortality was nil. CONCLUSIONS: In comparison with previously published literature on the topic, the major complication rate in this group of patients appears to be low.

Adolescent↗
PubMed2005

A follow-up study of infants with intracranial hemorrhage at full-term.

OBJECTIVE: To determine physical and cognitive outcomes of full-term infants who suffered intracranial hemorrhage (ICH) at birth. METHODS: A retrospective hospital-based, follow-up study of infants treated in London, Ontario between 1985 and 1996. Follow-up was conducted by telephone interviews and clinic visits. Outcome was measured according to physical and cognitive scales. Perinatal risk factors and hemorrhage characteristics were correlated with final outcome. RESULTS: For this study 66 infants with ICH were identified, of which seven died during the first week of life. We obtained follow-up in all but ten cases (median = 3-years; range 1.0 to 10.9 years). Overall, 57% of infants had no physical or cognitive deficits at follow-up. Death occurred most frequently among those with primarily subarachnoid hemorrhage (19%) and the most favorable outcomes occurred among those with subdural hemorrhage (80% had no disability). In univariate models, thrombocytopenia (platelet count < or = 70 x 10(9)/L), increasing overall hemorrhage severity, frontal location and spontaneous vaginal delivery as opposed to forceps-assisted delivery increased risk for poor outcome. In multivariate models, all these factors tended towards increased risk, but only thrombocytopenia remained significant for physical disability (OR = 7.6; 95% CI = 1.02 - 56.6); thrombocytopenia was borderline significant in similar models for cognitive disability (OR = 4.6; 95% CI = 0.9 - 23.9). CONCLUSION: Although forceps-assisted delivery may contribute to ICH occurrence, our study found better outcomes among these infants than those who had ICH following a spontaneous vaginal delivery. Hemorrhage in the frontal lobe was the most disabling hemorrhage location and if multiple compartments were involved, disability was also more likely to occur. However, in this report we found that the factor that was most likely to contribute to poor outcome was thrombocytopenia and this remained important in multivariate analysis.

Apgar Score↗
PubMed2004

Neurosurgery for the treatment of epilepsy.

PURPOSE OF REVIEW: Epilepsy is a common condition that is estimated to afflict 0.5-1.0% of the world's population. Frequently commencing in childhood, it is often associated with life-long disability. Approximately one-third of patients with epilepsy are refractory to antiepileptic drug therapy and many of these patients are candidates for surgical treatment. A growing body of evidence supports the safety and efficacy of surgery for the treatment of selected patients with epilepsy. Little information is available in the anesthesia literature regarding the presurgical assessment of candidates for surgical treatment. RECENT FINDINGS: The presurgical identification of suitable candidates involves a multidisciplinary approach to assessment. Recent advances, particularly in neuroimaging techniques, are dramatically enhancing the capacity to accurately identify patients who are most likely to benefit from surgery. Epilepsy surgery is underused worldwide and in developed countries. In view of current efforts to increase opportunities to provide surgical treatment to more patients and to offer surgery earlier in the course of the disorder, the number of patients requiring specialized perioperative anesthetic care is expected to increase. SUMMARY: This article provides anesthesiologists with an overview of the assessment process, investigation techniques and current rationale that influence the selection of appropriate candidates for surgical treatment and the associated need for specialized anesthetic care.

Journal Article↗