Biomedical subjects

David Crabbe

Publications and source records attributed to David Crabbe.

3 recordsLinked to original sources

PubMed2003

Percutaneous endoscopic gastrostomy. Procedure in practice.

Percutaneous endoscopic gastrostomy (PEG) is a relatively common procedure used in the treatment of children. As with all procedures, it must be used with care and only after taking careful account of circumstances and likely responses of the individual patient. This first of two articles on the procedure discusses the indications and contraindications for PEG insertion in children and then focuses on the procedure itself. The second article will discuss the role of the nurse as surgeon's assistant in the application of this procedure to children.

Child↗

PubMed2003

Nurse-assisted PEG in children.

The procedures reviewed in this article comprised 83 PEG insertions and 39 PEG changes in children aged six weeks to 19 years (median three years) with weights between 4.7 kg and 80 kg (median 13.5 kg). The complication rate was lower than previously reported paediatric series performed exclusively by medical practitioners. Four children required open conversion and one gastro-colic fistula was discovered five months later.

Adolescent↗

PubMed2002

A simulation to evaluate screening for Helicobacter pylori infection in the prevention of peptic ulcers and gastric cancers.

A discrete event simulation model has evaluated a screening programme for Helicobacter pylori infection (H. pylori) in which individuals under the age of 50 years would be screened once. Eradication of H. pylori would reduce the peptic ulcer risk immediately and the gastric cancer risk after a fixed delay. The data were derived from published databases and peer reviewed papers. The simulation model, using variance reduction techniques, predicted that a screening programme would reduce morbidity and deaths but could cost around 19 million pounds for England and Wales in the first year of screening. A factorial design analysis showed the sensitivity of key variables. An increase in the opportunistic testing was found significantly to reduce the impact of screening.

Adult↗