First case of sialolithiasis associated with atomoxetine.
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Biomedical subjects
Publications and source records attributed to David Gardner.
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Patients with type 2 diabetes are known to have an elevated risk of cardiovascular morbidity and mortality. Prior to the development of hyperglycemia and type 2 diabetes, individuals undergo a prolonged prediabetic phase involving hyperglycemia and insulin resistance. This has been associated with increased cardiovascular risk and is considered a cardiovascular risk equivalent. It is well known that dyslipidemia is an important contributor to the development of coronary artery disease. Treating diabetes with lipid-lowering agents reduces patients' cardiovascular risk. Preliminary studies have shown that similar benefits are seen even in persons with prediabetes. Hence, lipid-lowering agents should be considered not only in patients with type 2 diabetes, but also in individuals with prediabetes and with elevated lipid levels.
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The worldwide increase in the prevalence of obesity, and the dire health consequences of this increase, has been well-documented. In this review of obesity, we will examine possible mechanisms for this increase and what the implications are for prevention and treatment of this vital public health problem.
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