Biomedical subjects
Publications and source records attributed to David P Leader.
UNLABELLED: BugView is a Java application for visualizing homologous genes on a pair of related genomes, and can also be used to view individual genomes. It accepts files of prokaryotic or eukaryotic genomes in GenBank format and allows users to assign homologous pairs, and make and save annotations. AVAILABILITY: http://www.gla.ac.uk/~dpl1n/BugView/
The study of polygenic disorders such as cardiovascular and metabolic diseases requires access to vast amounts of experimental and in silico data. Where animal models of disease are being used, visualization of syntenic genome regions is one of the most important tools supporting data analysis. We define what is required to visualize synteny in terms of the data being displayed, the screen layout, and user interaction. We then describe a prototype visualization tool, SyntenyVista, which provides integrated access to quantitative trait loci, microarray, and gene datasets. We believe that SyntenyVista is a significant step towards an improved representation of comparative genomics data.
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