Biomedical subjects

David V Budescu

Publications and source records attributed to David V Budescu.

4 recordsLinked to original sources

PubMed2004

Evidence that androgenic and estrogenic metabolites contribute to the effects of dehydroepiandrosterone on cognition in postmenopausal women.

Prior studies of the effects of dehydroepiandrosterone (DHEA) on cognition have produced complex and inconsistent results. We hypothesize that these results may arise, in part, because of DHEA's metabolism into estrogens and androgens that produce opposing effects on cognition. Our study administered 50 mg of oral DHEA daily for 4 weeks in a placebo-controlled crossover design to six postmenopausal women. We measured blood levels of androgens (total testosterone, free testosterone, DHEA, DHEAS), estrogens (estradiol, estrone), and cognitive performance on recognition memory, perceptual identification, digit span memory, and visual attentional vigilance under both drug and placebo conditions. Multiple regression models incorporating the factors of age and body mass index (BMI) were used to ascertain the relation between sex steroids and cognitive performance. Our results demonstrated that estrogens produced a positive effect on recognition memory, while androgens produced a negative effect. This pattern reversed in perceptual identification with estrogens producing a negative effect and androgens producing a positive effect. In addition, BMI produced a negative effect on digit span memory, age produced a negative effect on perceptual identification, and androgens produced a negative effect on visual attentional vigilance. These results help, in part, to explain DHEA's complex effects on cognition. The diverse effects of sex steroids across tasks underscore the importance of identifying the specific cognitive mechanisms influenced by sex steroids and emphasizes that one should not expect sex steroids to produce homogeneous effects across cognitive tasks.

Aged↗

PubMed2004

You say "probable" and I say "likely": improving interpersonal communication with verbal probability phrases.

When forecasters and decision makers describe uncertain events using verbal probability terms, there is a risk of miscommunication because people use different probability phrases and interpret them in different ways. In an effort to facilitate the communication process, the authors investigated various ways of converting the forecasters' verbal probabilities to the decision maker's terms. The authors present 3 studies in which participants judged the probabilities of distinct events using both numerical and verbal probabilities. They define several indexes of interindividual coassignment of phrases to the same events and evaluate the conversion methods by comparing the values of these indexes for the converted and the unconverted judgments. In all the cases studied, the conversion methods significantly reduced the error rates in communicating uncertainties.

Adolescent↗

PubMed2003

Decision making under internal uncertainty: the case of multiple-choice tests with different scoring rules.

This paper assesses framing effects on decision making with internal uncertainty, i.e., partial knowledge, by focusing on examinees' behavior in multiple-choice (MC) tests with different scoring rules. In two experiments participants answered a general-knowledge MC test that consisted of 34 solvable and 6 unsolvable items. Experiment 1 studied two scoring rules involving Positive (only gains) and Negative (only losses) scores. Although answering all items was the dominating strategy for both rules, the results revealed a greater tendency to answer under the Negative scoring rule. These results are in line with the predictions derived from Prospect Theory (PT) [Econometrica 47 (1979) 263]. The second experiment studied two scoring rules, which allowed respondents to exhibit partial knowledge. Under the Inclusion-scoring rule the respondents mark all answers that could be correct, and under the Exclusion-scoring rule they exclude all answers that might be incorrect. As predicted by PT, respondents took more risks under the Inclusion rule than under the Exclusion rule. The results illustrate that the basic process that underlies choice behavior under internal uncertainty and especially the effect of framing is similar to the process of choice under external uncertainty and can be described quite accurately by PT.

Choice Behavior↗

PubMed2003

The dominance analysis approach for comparing predictors in multiple regression.

A general method is presented for comparing the relative importance of predictors in multiple regression. Dominance analysis (D. V. Budescu, 1993), a procedure that is based on an examination of the R2 values for all possible subset models, is refined and extended by introducing several quantitative measures of dominance that differ in the strictness of the dominance definition. These are shown to be intuitive, meaningful, and informative measures that can address a variety of research questions pertaining to predictor importance. The bootstrap is used to assess the stability of dominance results across repeated sampling, and it is shown that these methods provide the researcher with more insights into the pattern of importance in a set of predictors than were previously available.

Algorithms↗