Biomedical subjects

David Zadok

Publications and source records attributed to David Zadok.

21 records · Page 2Linked to original sources

PubMed2002

Intraocular pressure after LASIK for hyperopia.

PURPOSE: To determine whether hyperopic laser in situ keratomileusis (H-LASIK) affects Goldmann applanation tonometry measurements. DESIGN: Retrospective, comparative, self-controlled case series. PARTICIPANTS: One hundred eight eyes of 58 patients were enrolled in the study. METHODS: Baseline intraocular pressure (IOP) was measured by Goldmann applanation tonometry. These readings were compared with readings obtained at least 6 months after surgery. RESULTS: After H-LASIK, a decrease was observed in the measured IOP of treated eyes that could not be related to the degree of hyperopia treated or to the treatment zone diameter. A significant difference was observed between the IOP before and after surgery (P < 0.00001). CONCLUSIONS: The applanation tonometer underestimates the true IOP after LASIK for hyperopia.

Adult↗

PubMed2002

Laser-assisted subepithelial keratectomy versus photorefractive keratectomy for the correction of myopia. A prospective comparative study.

PURPOSE: To compare the early postoperative visual rehabilitation after laser-assisted subepithelial keratectomy (LASEK) and photorefractive keratectomy (PRK) for the correction of myopia. SETTING: CODET Aris Vision Institute, Tijuana, Mexico. METHODS: This prospective study included 50 eyes of 25 patients with myopia who received LASEK in 1 eye and PRK in the contralateral eye. Excimer laser corneal ablation was done using the Nidek EC-5000 excimer laser. Patients were seen at 1 and 3 days, 1 week, and 1 month. Discomfort, subjective uncorrected visual acuity (UCVA), objective UCVA, best corrected visual acuity (BCVA), corneal clarity (haze), and time for corneal reepithelialization were analyzed. RESULTS: Seventy-two percent and 80% of the LASEK eyes had more discomfort at 1 day and 3 days, respectively. Eighty percent and 96% of the PRK eyes had better subjective UCVA at 1 day and 3 days, respectively. Corneas were fully reepithelialized at a mean of 3.3 days +/- 0.5 (SD) and 3.6 +/- 0.5 days in the PRK and LASEK groups, respectively. At 1 month, the UCVA was similar in both groups; no eye had lost lines of BCVA or developed haze. CONCLUSIONS: Both LASEK and PRK were effective and safe procedures in the surgical correction of myopia at the 1-month postoperative visit. Patients reported less discomfort and better visual acuity in their PRK eye during the early postoperative period. Patients should be informed that LASEK, whose acronym is similar to that of laser in situ keratomileusis, has a recovery speed that is similar to that of surface laser refractive procedures such as PRK.

Adult↗

PubMedDate not supplied

Systemic side effects of ophthalmic drops.

Topical application of ocular drugs may cause serious adverse ocular or systemic side effects. Children are at greater risk for systemic side effects because ocular dosing is not weight-adjusted, and infants are especially vulnerable as a consequence of the inability to efficiently metabolize the drug, and/or an immature blood-brain barrier. Four pediatric patients are reported in whom treatment with topical brimonidine, a selective alpha-2 adrenoceptor agonist, indicated for the treatment of glaucoma, produced somnolence. Anti-glaucoma eyedrops that are not approved for use in children are still used frequently in pediatrics. Therefore, physicians should be aware of possible systemic side effects of ophthalmic drops.

Administration, Topical↗