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Biomedical subjects

Deepak Kamat

Publications and source records attributed to Deepak Kamat.

At least 19 recordsLinked to original sources
PubMed2006

Rickets: not a disease of the past.

Rickets develops when growing bones fail to mineralize. In most cases, the diagnosis is established with a thorough history and physical examination and confirmed by laboratory evaluation. Nutritional rickets can be caused by inadequate intake of nutrients (vitamin D in particular); however, it is not uncommon in dark-skinned children who have limited sun exposure and in infants who are breastfed exclusively. Vitamin D-dependent rickets, type I results from abnormalities in the gene coding for 25(OH)D3-1-alpha-hydroxylase, and type II results from defective vitamin D receptors. The vitamin D-resistant types are familial hypophosphatemic rickets and hereditary hypophosphatemic rickets with hypercalciuria. Other causes of rickets include renal disease, medications, and malabsorption syndromes. Nutritional rickets is treated by replacing the deficient nutrient. Mothers who breastfeed exclusively need to be informed of the recommendation to give their infants vitamin D supplements beginning in the first two months of life to prevent nutritional rickets. Vitamin D-dependent rickets, type I is treated with vitamin D; management of type II is more challenging. Familial hypophosphatemic rickets is treated with phosphorus and vitamin D, whereas hereditary hypophosphatemic rickets with hypercalciuria is treated with phosphorus alone. Families with inherited rickets may seek genetic counseling. The aim of early diagnosis and treatment is to resolve biochemical derangements and prevent complications such as severe deformities that may require surgical intervention.

Breast Feeding↗
PubMed2006

A case of extrahepatic portal hypertension.

Bleeding from the proximal part of the gastrointestinal (GI) tract is not uncommon in children. Children could present with anemia secondary to chronic occult bleeding in the gastrointestinal tract or as anemia secondary to acute exsanguinations and can present in hypovolemic shock. There are various causes of upper GI bleeding in children. A systematic approach in evaluating these children is essential so that the diagnosis is made in timely manner and appropriate management is begun early.

Child↗
PubMed2005

Seizures in a 20-month-old native of Minnesota: a case of neurocysticercosis.

A 20-month-old child, native of Minnesota, was diagnosed with neurocysticercosis. He had no history of international travel or pork consumption. This case and review of the literature emphasize the need to consider neurocysticercosis in any child with nonfebrile seizures in the United States because international travel and exposure to international travelers have become so common throughout the world.

Animals↗